| wk | weak; week; work |
|---|---|
| WOWS | weak opiate withdrawal scale |
| WR | Wassermann reaction; water retention; weakly reactive; weak response; whole response; wiping reactio... |
| DABP | D site albumin promoter binding protein |
| ESP | early systolic paradox; echo spacing; effective sensory projection; effective systolic pressure; end... |
| W | weak |
|---|---|
| AdMLP | Adenovirus major late promoter |
| Ad2MLP | Adenovirus-2 major late promoter |
| COUP-TF | Chicken Ovalbumin Upstream Promoter Transcription Factor |
| COUP-TFII | Chicken ovalbumin upstream promoter transcription factor II |
| weak | 1. Wanting physical strength. Specifically: Deficient in strength of body; feeble; infirm; sickly; debilitated; enfeebled; exhausted. "A poor, infirm, weak, and despised old man." (Shak) "Weak with hunger, mad with love." (Dryden) Not able to sustain a great weight, pressure, or strain; as, a weak timber; a weak rope. Not firmly united or adhesive; easily broken or separated into pieces; not compact; as, a weak ship. Not stiff; pliant; frail; soft; as, the weak stalk of a plant. Not able to resist external force or onset; easily subdued or overcome; as, a weak barrier; as, a weak fortress. Lacking force of utterance or sound; not sonorous; low; small; feeble; faint. "A voice not soft, weak, piping, and womanish." (Ascham) Not thoroughly or abundantly impregnated with the usual or required ingredients, or with stimulating and nourishing substances; of less than the usual strength; as, weak tea, broth, or liquor; a weak decoction or solution; a weak dose of medicine. Lacking ability for an appropriate function or office; as, weak eyes; a weak stomach; a weak magistrate; a weak regiment, or army. 2. Not possessing or manifesting intellectual, logical, moral, or political strength, vigor, etc. Specifically: Feeble of mind; wanting discernment; lacking vigor; spiritless; as, a weak king or magistrate. "To think every thing disputable is a proof of a weak mind and captious temper." (Beattie) "Origen was never weak enough to imagine that there were two Gods." (Waterland) Resulting from, or indicating, lack of judgment, discernment, or firmness; unwise; hence, foolish. "If evil thence ensue, She first his weak indulgence will accuse." (Milton) Not having full confidence or conviction; not decided or confirmed; vacillating; wavering. "Him that is weak in the faith receive ye, but not to doubtful disputations." (Rom. Xiv. 1) Not able to withstand temptation, urgency, persuasion, etc.; easily impressed, moved, or overcome; accessible; vulnerable; as, weak resolutions; weak virtue. "Guard thy heart On this weak side, where most our nature fails." (Addison) Wanting in power to influence or bind; as, weak ties; a weak sense of honor of duty. Not having power to convince; not supported by force of reason or truth; unsustained; as, a weak argument or case. "Convinced of his weak arguing." "A case so weak . . . Hath much persisted in." (Hooker) Wanting in point or vigor of expression; as, a weak sentence; a weak style. Not prevalent or effective, or not felt to be prevalent; not potent; feeble. "Weak prayers." Lacking in elements of political strength; not wielding or having authority or energy; deficient in the resources that are essential to a ruler or nation; as, a weak monarch; a weak government or state. "I must make fair weather yet awhile, Till Henry be more weak, and I more strong." (Shak) Tending towards lower prices; as, a weak market. 3. Pertaining to, or designating, a verb which forms its preterit (imperfect) and past participle by adding to the present the suffix -ed, -d, or the variant form -t; as in the verbs abash, abashed; abate, abated; deny, denied; feel, felt. See Strong, 19 . Pertaining to, or designating, a noun in Anglo-Saxon, etc, the stem of which ends in -n. See Strong, 19 . Weak is often used in the formation of self-explaining compounds; as, weak-eyed, weak-handed, weak-hearted, weak-minded, weak-spirited, and the like. <medicine> Weak conjugation, a sore covered with pale, flabby, sluggish granulations. Origin: OE. Weik, Icel. Veikr; akin to Sw. Vek, Dan. Veg soft, flexible, pliant, AS. Wac weak, soft, pliant, D. Week, G. Weich, OHG. Weih; all from the verb seen in Icel. Vikja to turn, veer, recede, AS. Wican to yield, give way, G. Weichen, OHG. Wihhan, akin to Skr. Vij, and probably to E. Week, L. Vicis a change, turn, Gr. To yield, give way. 132. Cf. Week, Wink, Vicissitude. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| weak-hearted | Having little courage; of feeble spirit; dispirited; faint-hearted. "Weak-hearted enemies." Source: Websters Dictionary (01 Mar 1998) |
| weak-minded | Having a weak mind, either naturally or by reason of disease; feebleminded; foolish; idiotic. Weak"-mindedness. Source: Websters Dictionary (01 Mar 1998) |
| constituative promoter | An unregulated promoter that allows for continual transcription of itsassociated gene. (09 Oct 1997) |
| promoter | <molecular biology> A region of DNA to which RNA polymerase binds before initiating the transcription of DNA into RNA. The nucleotide at which transcription starts is designated +1 and nucleotides are numbered from this with negative numbers indicating upstream nucleotides and positive downstream nucleotides. most bacterial promoters contain two consensus sequences that seem to be essential for the binding of the polymerase. The first, the Pribnow box, is at about 10 and has the consensus sequence 5' TATAAT 3'. The second, the 35 sequence, is centred about 35 and has the consensus sequence 5' TTGACA 3'. most factors that regulate gene transcription do so by binding at or near the promoter and affecting the initiation of transcription. Much less is known about eukaryote promoters, each of the three RNA polymerases has a different promoter. RNA polymerase I recognises a single promoter for the precursor of rRNA. RNA polymerase II, that transcribes all genes coding for polypeptides, recognises many thousands of promoters. most have the Goldberg Hogness or TATA box that is centred around position 25 and has the consensus sequence 5' TATAAAA 3'. Several promoters have a CAAT box around 90 with the consensus sequence 5' GGCCAATCT 3'. There is increasing evidence that all promoters for housekeeping genes contain multiple copies of a GC rich element that includes the sequence 5' GGGCGG 3'. Transcription by polymerase II is also affected by more distant elements known as enhancers. RNA polymerase III synthesises 5s ribosomal RNA, all tRNAs and a number of small RNAs. The promoter for RNA polymerase III is located within the gene either as a single sequence, as in the 5s RNA gene or as two blocks, as in all tRNA genes. (13 Nov 1997) |
| promoter insertion | <molecular biology> Activation of a gene by the nearby integration of a virus. The long-terminal repeat acts as a promoter for the host gene. A form of insertional mutagenesis. (18 Nov 1997) |
| promoter regions | <genetics> DNA sequences which are recognised (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the pribnow box in bacteria and the tata box in eukaryotes. (12 Dec 1998) |
| down promoter mutation | <molecular biology> A mutation (a change in base pair sequence) in a promoter region, this results in lower gene expression (less transcription of the gene occurs). (09 Oct 1997) |
| tumour promoter | <molecular biology, oncology> Agent that in classical studies of carcinogenesis in rodent skin was able to increase the sensitivity of tumour formation by a previously applied primary carcinogen, but was unable to induce tumours when used alone. Important example was croton oil, active ingredients of which are now believed to be phorbol esters. These are believed to act as analogues of diacylglycerols and may activate protein kinase C. Strictly speaking, not the same as a co carcinogen, which is defined as being active when administered at the same time. Tumour promoters generally are carcinogens when tested more stringently. (18 Nov 1997) |
| up promoter mutation | A mutation that increases the frequency of initiation of transcription. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|