| VIN | vulvar intraepithelial neoplasm |
|---|---|
| CIN | Cervical Intraepithelial Neoplasia |
| CIN | central inhibition; cervical intraepithelial neoplasia; chronic interstitial nephritis |
| CIN1, | CIN I cervical intraepithelial neoplasia, grade 1 (mild dysplasia) |
| CIN | 2, CIN II cervical intraepithelial neoplasia, grade 2 (moderate-severe) |
| VIN | Vulvar Intraepithelial Neoplasia |
|---|---|
| AIN | Anal intraepithelial neoplasia |
| CIN 3 | Cervical Intraepithelial Neoplasia grade 3 |
| CIN III | Cervical intraepithelial neoplasia grade III |
| HGPIN | High grade prostatic intraepithelial neoplasia |
| cervical intraepithelial neoplasia | A term which describes precancerous changes to the epithelial cells lining the cervix. The diagnosis is made from the microscopic examination of a PAP smear acquired tissue specimen. Less than 5% of all PAP smears will show cervical dysplasia. The peak incidence is in women 25 to 35 years of age. Risk factors include multiple sexual partners, early onset of sexual activity (less than 18), early childbearing (less than 16) and past medical history of a sexually transmitted disease (for example genital warts, genital herpes, HIV infection). Treatment is based on the degree of dysplasia present, as judged by a pathologist. Treatments include cryotherapy and conisation. Origin: Gr. Plassein = to form (27 Sep 1997) |
|---|---|
| prostatic intraepithelial neoplasia | A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer. (12 Dec 1998) |
| vulvar | Vulval Relating to the vulva. (05 Mar 2000) |
| vulvar diseases | Diseases of the vulva. (12 Dec 1998) |
| vulvar dystrophy | A spectrum of vulvar eruptions consisting of white atrophic papules, including lichen sclerosus et atrophicus, squamous cell hyperplasia (hypertrophic dystrophy), or a combination of these (mixed dystrophy). See: lichen sclerosus et atrophicus. (05 Mar 2000) |
| vulvar slit | The cleft between the labia majora. Synonym: rima pudendi, fissura pudendi, pudendal cleavage, pudendal slit, rima vulvae, urogenital cleft, vulvar slit. (05 Mar 2000) |
| hereditary benign intraepithelial dyskeratosis | An autosomal dominant condition consisting of white spongy lesions of the buccal mucosa, floor of the mouth, ventral lateral tongue, gingiva and palate. Transient gelatinous plaques form over the cornea, which may produce temporary blindness, hereditary benign intraepithelial dyskeratosis. Synonym: hereditary benign intraepithelial dyskeratosis. (05 Mar 2000) |
| squamous intraepithelial lesion | A general term for the abnormal growth of squamous cells on the surface of the cervix. The changes in the cells are described as low grade or high grade, depending on how much of the cervix is affected and how abnormal the cells are. Also called sil. (12 Dec 1998) |
| intraepithelial | Within the layer of cells that forms the surface or lining of an organ. (12 Dec 1998) |
| intraepithelial carcinoma | Cancer that involves only the cells in which it began and has not spread to other tissues. Lobular carcinoma in situ is found in the lobules of the breast. Ductal carcinoma in situ (also called intraductal carcinoma) arises in the ducts. (16 Dec 1997) |
| intraepithelial dyskeratosis | An autosomal dominant condition consisting of white spongy lesions of the buccal mucosa, floor of the mouth, ventral lateral tongue, gingiva and palate. Transient gelatinous plaques form over the cornea, which may produce temporary blindness, hereditary benign intraepithelial dyskeratosis. Synonym: hereditary benign intraepithelial dyskeratosis. (05 Mar 2000) |
| intraepithelial glands | Accumulations of glandular cells that lie within an epithelium, as those of the urethra. (05 Mar 2000) |
| multiple endocrine neoplasia | (type I) This is a hereditary disorder in which two or more of the following glands: parathyroid, pancreas, pituitary, adrenals or thyroid develop hyperplasia or a tumour. (type II) This is a hereditary disorder in which two or more of the following glands: thyroid, adrenal or parathyroid, develop overgrowth (hyperplasia) or malignant cells (cancer). The underlying cause is genetic and a positive family history for this illness is a risk factor. Incidence: approximately 3 in 100,000 people in the general population. Origin: Gr. Plassein = to form (27 Sep 1997) |
| multiple endocrine neoplasia 1 | <radiology> Multiple endrocrine neoplasia syndrome three P's. Pituitary adenoma, 65% can develop Cushing's, acromegaly, prolactinoma, parathyroid hyperplasia / adenoma, 88% can develop hyper-PTH pancreatic isleT-cell tumour, gastrinoma (Z-E) most common, 50% of Z-E can develop MEN-1, inconstant features: bronchial/intestinal carcinoid, thyroid adenoma, adrenal cortical tumour, lipoma, thymoma tissue expression Primary hyperparathyroidism (90%), Gastrinoma (30%), Prolactinoma (15%), Other (10%). Synonym: Wermer syndrome (12 Dec 1998) |
| multiple endocrine neoplasia 2 | <radiology> Multiple endocrine neoplasia syndrome, medullary thyroid carcinoma, usually multifocal; metastasis to local nodes, lung, liver, usually calcify in liver, pheochromocytoma, almost always bilateral, parathyroid hyperplasia, may be secondary to calcitonin secreted by medullary thyroid carcinoma inconstant feature: adrenal cortical hyperplasia Synonym: Sipple syndrome (12 Dec 1998) |
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