| ¿µ¹® | osteomalacia | ÇÑ±Û | °ñ¿¬ÈÁõ |
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| ¼³¸í | ÁÖ·Î ºñŸ¹Î D°¡ ºÎÁ·ÇÏ¿© »ý±â´Â ±¸·çº´¿¡¼ º¼ ¼ö ÀÖ´Ù. ºñŸ¹Î D´Â Àå°ü¿¡¼ Ä®½·ÀÇ Èí¼ö¸¦ ÃËÁøÇϰí ÄáÆÏ¿¡¼ ¼Òº¯À¸·Î ¹è¼³µÇ´Â Ä®½·ÀÇ ¾çÀ» °¨¼Ò½ÃÄÑ Ç÷¾×³»¿¡ Ä®½·ÀÇ ¾çÀ» Áõ°¡½ÃŰ´Â ¿ªÇÒÀ» ÇÑ´Ù. µû¶ó¼ ÀÌ ºñŸ¹ÎÀÌ ºÎÁ·ÇÒ °æ¿ì »À¿¡ Ä§ÂøµÉ Ä®½·ÀÇ ¾çÀÌ °¨¼ÒÇÏ°Ô µÇ¹Ç·Î »À´Â ¿¬ÇØÁö°í Àß ºÎ·¯Áö±â ½¬¿î »óŰ¡ µÈ´Ù. Ä¡·á´Â ÀÌ·± ºñŸ¹ÎÀÇ º¹¿ëÀ̳ª, ȤÀº ü³»¿¡ Ä®½·À» ÁÖÀÔÇÏ¿© ü³»Ä®½·ÀÇ ¾çÀ» Áõ°¡½ÃŰ´Â °ÍÀÌ´Ù. |
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| ¿µ¹® | vitamin | ÇÑ±Û | ºñŸ¹Î |
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| ¼³¸í | »ýü¿¡ ²À ÇÊ¿äÇÑ ¿µ¾çºÐÀÌÁö¸¸, ³»ºÎ¿¡¼ ÇÕ¼ºµÇÁö ¾ÊÀ¸¹Ç·Î ¹Ýµå½Ã ¿ÜºÎ¿¡¼ º¸ÃæÇؾ߸¸ µÇ´Â °ÍÀ» ¸»ÇÑ´Ù. ºÎÁ·½Ã »ý¸íÀ¯Áö°¡ ¾î·Á¿ì¸ç, ƯÈ÷ ÀϺΠºñŸ¹ÎÀº °ú´Ù½Ã¿¡µµ ÀÌ»óÀ» À¯¹ßÇϹǷΠÇ×»ó ÀûÁ¤¼öÁØÀ» À¯ÁöÇØ¾ß ÇÑ´Ù. ºñŸ¹Î A, D, E, K´Â Áö¿ë¼º ºñŸ¹ÎÀ¸·Î ÃàÀûÀÌ °¡´ÉÇϳª, ³ª¸ÓÁö´Â ¼ö¿ë¼ºÀ¸·Î ¸ÅÀÏ ¼·ÃëÇØ¾ß ÇÑ´Ù. ºñŸ¹Î B2(vitamin B2) RiboflavinÀ̶ó°íµµ ÇÔ. ÁÖ·Î ¿ìÀ¯, Ä¡Áî, °è¶õ, °£, µî¿¡ ¸¹´Ù. ºÎÁ·½Ã ÀÔ¼úÁÖÀ§°¡ °¥¶óÁö´Â ÀÔ¼ú¿°, ÀÔ¼ú¾È¿¡ ¿°ÁõÀÌ »ý±â´Â ÀԾȿ°, ±×¸®°í °¢Á¾ ÇǺκ´ µîÀÌ ¹ß»ýÇÑ´Ù. ÁÖ·Î °¡³ÇÑ ÈÄÁø±¹¿¡ ¸¹ÀÌ ¹ß»ýÇϸç, ÀϺΠ¿©¼º¿¡¼ Áö³ªÄ£ ´ÙÀÌ¾îÆ®·Î ÀÎÇØ ¹ß»ýÇϱ⵵ ÇÑ´Ù. ºñŸ¹Î B6(vitamin B6) À̰ÍÀº pyridoxineÀ̶ó°íµµ ºÎ¸£¸ç pyridoxine, pyridoxal ¹× pyridoxamine ¼¼ °¡ÁöÀÇ ÈÇÕ¹°ÀÌ ÀÖ´Ù. À̵éÀº ¸ðµÎ ü³»¿¡¼ pyridoxal phosphate·Î Ȱ¼ºÈµÇ¾î Á¶È¿¼Ò·Î ÀÛ¿ëÇÑ´Ù. À̴ ü³» ¾Æ¹Ì³ë»ê ´ë»ç¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÏ´Â Á¶È¿¼ÒÀÌ´Ù. ÀÌ ºñŸ¹ÎÀÌ °áÇÌµÇ¸é ´Ù¹ß¼º ¸»ÃʽŰ濰, ºóÇ÷ ¹× ÇǺκ´ÀÌ »ý±ä´Ù. ºñŸ¹Î B12(vitamin B12) ÀûÇ÷±¸ÀÇ »ý¼º¿¡ ÇʼöºÒ°¡°áÇÑ ºñŸ¹ÎÀÌ´Ù. ºÎÁ·½Ã Ư¡ÀûÀÎ ´ëÀûÇ÷¸ð±¸)°¡ Ç÷¾×³»¿¡¼ °üÂûµÈ´Ù. ´ëºÎºÐÀÇ ½Ä»çÇÏ´Â ¹°Áú¿¡ µé¾îÀÖÀ¸¹Ç·Î ÀÎüÀÇ ³»ÀûÀÌ»óÀÌ ÀÖÁö ¾Ê°í´Â Àß ¹ß»ýÇÏÁö ¾Ê´Â´Ù. ´ëÇ¥ÀûÀÎ °æ¿ì°¡ ¾Ç¼ººóÇ÷·Î½á, ÀÌ ºñŸ¹ÎÀº À§¿¡¼ ºÐºñµÇ´Â ³»ÀÎÀÚ(intrinsic factor)¿Í ÀÌÀÚÈ¿¼ÒÀÇ ÀÛ¿ëÀÌ ÀÖ¾î¾ß¸¸ Èí¼ö°¡ µÇ´Â µ¥, ¸¸¾à ¿©±â¿¡ ÀÌ»óÀÌ ÀÖÀ¸¸é Á¦´ë·Î Èí¼ö°¡ µÇÁö ¾ÊÀ¸¹Ç·Î Ç÷¾×³»¿¡ Á¤»óÀûÇ÷±¸ÀÇ °¨¼Ò¿Í °Å´ëÀûÇ÷±¸ÀÇ Áõ°¡°¡ ³ªÅ¸³ª, ºóÇ÷ÀÌ ¹ß»ýÇÑ´Ù. ÀÌ ºóÇ÷¿¡ ´ëÇÑ Áø´ÜÀº ½¯¸µ°Ë»ç(Schilling test)·Î½á °¡´ÉÇϸç, Ä¡·á´Â ºñŸ¹ÎÀÇ Åõ¿©ÀÌ´Ù. ºñŸ¹Î C(vitamin C) ÁַΠǪ¸¥ ä¼Ò¿¡ ¸¹´Ù. ¿¾³¯¿¡ ¼¾ç¿¡¼ ¹è¸¦ Ÿ°í Ç×ÇØÇÏ´ø »ç¶÷µé¿¡°Ô¼ ÀÌÀ¯¸¦ ¾Ë ¼ö ¾ø´Â ÀæÀº ÃâÇ÷°ú ¸ÛÀ¸·Î ÀÚÁÖ »ç¸ÁÇÏ´Â °æ¿ì°¡ »ý°Ü ±«Ç÷º´(scurvy)À̶ó°í ºÒ¸®¿ü´Ù. ³ªÁß¿¡ ±× ÀÌÀ¯°¡ Ǫ¸¥ ä¼ÒÀÇ ¼·ÃëºÎÁ·À¸·Î ÀÎÇÑ ºñŸ¹ÎC °áÇÌÀÎ °ÍÀ» ¾Ë¾Ò´Ù. ÀÌ ºñŸ¹ÎÀº °áÇÕÁ¶Á÷ÀÇ Çü¼º¿¡ Áß¿äÇÑ ÀÛ¿ëÀ» ÇϹǷΠ¸¸¾à ºÎÁ·½Ã °áüÁ¶Á÷ÀÇ Çü¼ºÀÌ Á¦´ë·Î ÀϾÁö ¾Ê¾Æ Ç÷°üÀÌ ¼Õ»óµÇ¾î ÀæÀº ÃâÇ÷°ú ¸ÛÀÌ µé¸é Àß ³´Áö ¾Ê´Â Áõ»ó, ±×¸®°í °áÇÕÁ¶Á÷ÀÌ ÀÖ´Â »À¿¡µµ ÀÌ»óÀÌ ¹ß»ýÇÑ´Ù. Ä¡·á´Â ºñŸ¹ÎÀÇ ¼·ÃëÀÌ´Ù. ºñŸ¹Î D(vitamin D) Ç÷ÁßÄ®½·³óµµÀÇ Á¶Àý¿¡ Áß¿äÇÑ ÀÛ¿ëÀ» ÇÑ´Ù. ÀÌ ºñŸ¹ÎÀº À§Ã¢ÀÚ°ü¿¡¼ÀÇ Ä®½·Èí¼ö¸¦ ÃËÁøÇϰí, ¼Òº¯À¸·ÎÀÇ ¹è¼³À» °¨¼Ò½ÃÄÑ, Ç÷ÁßÄ®½·³óµµ¿Í Àλ꿰³óµµÀÇ Áõ°¡¸¦ °¡Á®¿Â´Ù. µû¶ó¼ ¼Ò¾Æ±â¿¡¼ °¨¼Ò½Ã »ÀÀÇ ¼ºÀåÀÌ ¾î·Æ°í, ½±°Ô ºÎ·¯Áö´Â °æÇâÀ» °¡Áö°í, ½ÉÇÏ¸é °öÃß°¡ µÇ´Â ±¸·çº´(rickets)ÀÌ ¹ß»ýÇÑ´Ù. ¼ºÀο¡¼ °¨¼Ò½Ã¿¡´Â »ÀÀÇ Ä®½·³óµµ°¡ °¨¼ÒÇÏ¿© »ý±â´Â °ñ¿¬ÈÁõ(osteomalacia)ÀÌ ¹ß»ýÇÑ´Ù. Ä¡·á´Â ºñŸ¹ÎÀÇ Åõ¿©ÀÌ´Ù. ºñŸ¹Î E(vitamin E) ÁַΠǪ¸¥ ÀÙÀ» °¡Áø ä¼Ò¿Í ±Í¸®(wheat germ)¿¡ ¸¹´Ù. »ê¼Ò¿¡ ´ëÇÑ µ¶¼ºÀ» °¨¼Ò½ÃŰ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ¾î, »ê¼Òµ¶¼ºÀ¸·Î ¹ß»ýµÇ´Â °ÍÀ¸·Î ÃßÁ¤µÇ´Â ¹Ì¼÷¾Æ¸Á¸·ÁõÀÇ ¿¹¹æ¿¡ »ç¿ëµÈ´Ù. ¶ÇÇÑ ºÎÁ·½Ã ¿ëÇ÷ÀÌ ÀϾÙ. ºñŸ¹Î K(vitamin K) °£¿¡¼ ¸¸µé¾îÁö´Â Ç÷¾×ÀÀ°í¹°ÁúÀÇ »ý¼º¿¡ ÇʼöÀûÀÌ´Ù. µû¶ó¼ ºÎÁ·½Ã Ç÷¾×ÀÀ°í°¡ ÀÌ·ç¾îÁöÁö ¾Ê¾Æ Á¶±×¸¸ »óó¿¡µµ ÃâÇ÷°æÇâÀ» º¸ÀδÙ. ÁÖ·Î °£, ä¼Ò±â¸§, ÀÙÀ» °¡Áø ä¼Ò µî¿¡ ¸¹´Ù. ´ë°³ ºÎÁ·Àº ½Å»ý¾Æ¿¡°Ô¼ ¸¹ÀÌ °üÂûµÈ´Ù. |
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| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
|---|---|
| HVDRR | hypocalcemic vitamin D-resistant rickets |
| VDRR | vitamin D-resistant rickets |
| OM | obtuse mental; occipitomental; occupational medicine; ocular movement; oculomotor; Osborne Mendel [r... |
| SR | sarcoplasmic reticulum; saturation recovery; scanning radiometer; screen; secretion rate; sedimentat... |
| OM | Osteomalacia |
|---|---|
| VDRR | Vitamin D resistant rickets |
| 1,25(OH)(2)D(3) | 1, 25(OH)(2) Vitamin D(3 |
| 1,25-D | 1, 25-dihydroxy vitamin D |
| VD3 | 1,25-dihydroxy-Vitamin D3 |
PDGF (Ç÷¼ÒÆÇ À¯·¡ ¼ºÀå ÀÎÀÚ
| vitamin d-resistant rickets | <radiology> X-linked recessive, defect in renal tubular resorption of phosphate, presents at 1 yr, progressive limb deformities X-ray: less severe changes than other rickets, presents later Differential diagnosis features: family hx, normal serum calcium, marked hypophosphataemia (decreased PO4), no secondary hyperparathyroidism (12 Dec 1998) |
|---|---|
| pseudo-osteomalacia | Rachitic softening of bone. (05 Mar 2000) |
| senile osteomalacia | Osteoporosis in the aged. (05 Mar 2000) |
| infantile osteomalacia | <rheumatology, orthopaedics> A condition caused by deficiency of vitamin D, especially in infancy and childhood, with disturbance of normal ossification. The disease is marked by bending and distortion of the bones under muscular action, by the formation of nodular enlargements on the ends and sides of the bones, by delayed closure of the fontanelles, pain in the muscles and sweating of the head. Vitamin D and sunlight together with an adequate diet are curative, provided that the parathyroid glands are functioning properly. Origin: Gr. Rhachitis = a spinal complaint (18 Nov 1997) |
| osteomalacia | <pathology> A condition marked by softening of the bones (due to impaired mineralisation, with excess accumulation of osteoid), with pain, tenderness, muscular weakness, anorexia and loss of weight, resulting from deficiency of vitamin D and calcium. Origin: Gr. Malakia = softness (18 Nov 1997) |
| antibiotic-resistant | Indicating microorganisms that continue to multiply although exposed to antibiotic agents. (05 Mar 2000) |
| vancomycin resistant enterococcus | A form of intestinal bacteria (formerly classed under streptococcus faecalis) which is not sensitive to the big gun antibiotic, vancomycin. This organism is usually only fatal in those who are, for reasons of age or infirmity, immunosuppressed. The pathology of the illness is exacerbated when haemosepsis (blood-stream infection) develops. (09 Oct 1997) |
| vasopressin-resistant diabetes | Diabetes insipidus due to inability of the kidney tubules to respond to antidiuretic hormone; X-linked inheritance, with full expression in males and partial defect in heterozygous females. Synonym: vasopressin-resistant diabetes. (05 Mar 2000) |
| resistant | Making or having powers of resistance, resisting. (18 Nov 1997) |
| resistant ovary syndrome | <syndrome> An obsolete term for amenorrhoea associated with hypergonadotrophism and normal ovarian follicles. Synonym: resistant ovary syndrome. Origin: after the surname of the first reported patient (05 Mar 2000) |
| multiple drug resistant tuberculosis | A strain of TB that does not respond to two or more standard anti-TB drugs. MDR-TB usually occurs when treatment is interrupted thus allowing mutations in the organism to occur that confer drug resistance. (09 Oct 1997) |
| drug resistant | Unresponsive to the desired effects of drugs or other therapy for example: irradiation cytotoxic agents or hormones. Drug resistance of cells within tumours is probably the major cause of treatment failure. (16 Dec 1997) |
| tartrate-resistant acid phosphatase | <biochemistry, enzyme> Acid phosphatase is present in bone, prostate, platelets, erythrocytes and spleen. Osteoclasts contain an isoenzyme that is resistant to tartrate, whereas, the isoenzyme in the prostate is sensitive. Tartrate-resistant acid phosphatase is elevated in the serum of patients with primary hypoparathyroidism, Paget disease, vertebral osteoporosis, T-cell lymphoma and in women after oophorectomy. Oestrogen replacement in osteoporotic postmenopausal women is associated with a decrease in tartrate-resistant acid phosphatase of 70% over 3 to 6 months. Acronym: TRAP (16 Dec 1997) |
| tuberculosis, multidrug-resistant | Tuberculosis resistant to chemotherapy with two or more antitubercular agents. The problem of resistance is particularly troublesome in tuberculosis as an opportunistic disease in HIV infection. (12 Dec 1998) |
| ketosis-resistant diabetes | Type II or adult onset diabetes mellitus, in which episodes of ketoacidosis rarely occur. (05 Mar 2000) |
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