| ¿µ¹® | vitamin | ÇÑ±Û | ºñŸ¹Î |
|---|---|---|---|
| ¼³¸í | »ýü¿¡ ²À ÇÊ¿äÇÑ ¿µ¾çºÐÀÌÁö¸¸, ³»ºÎ¿¡¼ ÇÕ¼ºµÇÁö ¾ÊÀ¸¹Ç·Î ¹Ýµå½Ã ¿ÜºÎ¿¡¼ º¸ÃæÇؾ߸¸ µÇ´Â °ÍÀ» ¸»ÇÑ´Ù. ºÎÁ·½Ã »ý¸íÀ¯Áö°¡ ¾î·Á¿ì¸ç, ƯÈ÷ ÀϺΠºñŸ¹ÎÀº °ú´Ù½Ã¿¡µµ ÀÌ»óÀ» À¯¹ßÇϹǷΠÇ×»ó ÀûÁ¤¼öÁØÀ» À¯ÁöÇØ¾ß ÇÑ´Ù. ºñŸ¹Î A, D, E, K´Â Áö¿ë¼º ºñŸ¹ÎÀ¸·Î ÃàÀûÀÌ °¡´ÉÇϳª, ³ª¸ÓÁö´Â ¼ö¿ë¼ºÀ¸·Î ¸ÅÀÏ ¼·ÃëÇØ¾ß ÇÑ´Ù. ºñŸ¹Î B2(vitamin B2) RiboflavinÀ̶ó°íµµ ÇÔ. ÁÖ·Î ¿ìÀ¯, Ä¡Áî, °è¶õ, °£, µî¿¡ ¸¹´Ù. ºÎÁ·½Ã ÀÔ¼úÁÖÀ§°¡ °¥¶óÁö´Â ÀÔ¼ú¿°, ÀÔ¼ú¾È¿¡ ¿°ÁõÀÌ »ý±â´Â ÀԾȿ°, ±×¸®°í °¢Á¾ ÇǺκ´ µîÀÌ ¹ß»ýÇÑ´Ù. ÁÖ·Î °¡³ÇÑ ÈÄÁø±¹¿¡ ¸¹ÀÌ ¹ß»ýÇϸç, ÀϺΠ¿©¼º¿¡¼ Áö³ªÄ£ ´ÙÀÌ¾îÆ®·Î ÀÎÇØ ¹ß»ýÇϱ⵵ ÇÑ´Ù. ºñŸ¹Î B6(vitamin B6) À̰ÍÀº pyridoxineÀ̶ó°íµµ ºÎ¸£¸ç pyridoxine, pyridoxal ¹× pyridoxamine ¼¼ °¡ÁöÀÇ ÈÇÕ¹°ÀÌ ÀÖ´Ù. À̵éÀº ¸ðµÎ ü³»¿¡¼ pyridoxal phosphate·Î Ȱ¼ºÈµÇ¾î Á¶È¿¼Ò·Î ÀÛ¿ëÇÑ´Ù. À̴ ü³» ¾Æ¹Ì³ë»ê ´ë»ç¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÏ´Â Á¶È¿¼ÒÀÌ´Ù. ÀÌ ºñŸ¹ÎÀÌ °áÇÌµÇ¸é ´Ù¹ß¼º ¸»ÃʽŰ濰, ºóÇ÷ ¹× ÇǺκ´ÀÌ »ý±ä´Ù. ºñŸ¹Î B12(vitamin B12) ÀûÇ÷±¸ÀÇ »ý¼º¿¡ ÇʼöºÒ°¡°áÇÑ ºñŸ¹ÎÀÌ´Ù. ºÎÁ·½Ã Ư¡ÀûÀÎ ´ëÀûÇ÷¸ð±¸)°¡ Ç÷¾×³»¿¡¼ °üÂûµÈ´Ù. ´ëºÎºÐÀÇ ½Ä»çÇÏ´Â ¹°Áú¿¡ µé¾îÀÖÀ¸¹Ç·Î ÀÎüÀÇ ³»ÀûÀÌ»óÀÌ ÀÖÁö ¾Ê°í´Â Àß ¹ß»ýÇÏÁö ¾Ê´Â´Ù. ´ëÇ¥ÀûÀÎ °æ¿ì°¡ ¾Ç¼ººóÇ÷·Î½á, ÀÌ ºñŸ¹ÎÀº À§¿¡¼ ºÐºñµÇ´Â ³»ÀÎÀÚ(intrinsic factor)¿Í ÀÌÀÚÈ¿¼ÒÀÇ ÀÛ¿ëÀÌ ÀÖ¾î¾ß¸¸ Èí¼ö°¡ µÇ´Â µ¥, ¸¸¾à ¿©±â¿¡ ÀÌ»óÀÌ ÀÖÀ¸¸é Á¦´ë·Î Èí¼ö°¡ µÇÁö ¾ÊÀ¸¹Ç·Î Ç÷¾×³»¿¡ Á¤»óÀûÇ÷±¸ÀÇ °¨¼Ò¿Í °Å´ëÀûÇ÷±¸ÀÇ Áõ°¡°¡ ³ªÅ¸³ª, ºóÇ÷ÀÌ ¹ß»ýÇÑ´Ù. ÀÌ ºóÇ÷¿¡ ´ëÇÑ Áø´ÜÀº ½¯¸µ°Ë»ç(Schilling test)·Î½á °¡´ÉÇϸç, Ä¡·á´Â ºñŸ¹ÎÀÇ Åõ¿©ÀÌ´Ù. ºñŸ¹Î C(vitamin C) ÁַΠǪ¸¥ ä¼Ò¿¡ ¸¹´Ù. ¿¾³¯¿¡ ¼¾ç¿¡¼ ¹è¸¦ Ÿ°í Ç×ÇØÇÏ´ø »ç¶÷µé¿¡°Ô¼ ÀÌÀ¯¸¦ ¾Ë ¼ö ¾ø´Â ÀæÀº ÃâÇ÷°ú ¸ÛÀ¸·Î ÀÚÁÖ »ç¸ÁÇÏ´Â °æ¿ì°¡ »ý°Ü ±«Ç÷º´(scurvy)À̶ó°í ºÒ¸®¿ü´Ù. ³ªÁß¿¡ ±× ÀÌÀ¯°¡ Ǫ¸¥ ä¼ÒÀÇ ¼·ÃëºÎÁ·À¸·Î ÀÎÇÑ ºñŸ¹ÎC °áÇÌÀÎ °ÍÀ» ¾Ë¾Ò´Ù. ÀÌ ºñŸ¹ÎÀº °áÇÕÁ¶Á÷ÀÇ Çü¼º¿¡ Áß¿äÇÑ ÀÛ¿ëÀ» ÇϹǷΠ¸¸¾à ºÎÁ·½Ã °áüÁ¶Á÷ÀÇ Çü¼ºÀÌ Á¦´ë·Î ÀϾÁö ¾Ê¾Æ Ç÷°üÀÌ ¼Õ»óµÇ¾î ÀæÀº ÃâÇ÷°ú ¸ÛÀÌ µé¸é Àß ³´Áö ¾Ê´Â Áõ»ó, ±×¸®°í °áÇÕÁ¶Á÷ÀÌ ÀÖ´Â »À¿¡µµ ÀÌ»óÀÌ ¹ß»ýÇÑ´Ù. Ä¡·á´Â ºñŸ¹ÎÀÇ ¼·ÃëÀÌ´Ù. ºñŸ¹Î D(vitamin D) Ç÷ÁßÄ®½·³óµµÀÇ Á¶Àý¿¡ Áß¿äÇÑ ÀÛ¿ëÀ» ÇÑ´Ù. ÀÌ ºñŸ¹ÎÀº À§Ã¢ÀÚ°ü¿¡¼ÀÇ Ä®½·Èí¼ö¸¦ ÃËÁøÇϰí, ¼Òº¯À¸·ÎÀÇ ¹è¼³À» °¨¼Ò½ÃÄÑ, Ç÷ÁßÄ®½·³óµµ¿Í Àλ꿰³óµµÀÇ Áõ°¡¸¦ °¡Á®¿Â´Ù. µû¶ó¼ ¼Ò¾Æ±â¿¡¼ °¨¼Ò½Ã »ÀÀÇ ¼ºÀåÀÌ ¾î·Æ°í, ½±°Ô ºÎ·¯Áö´Â °æÇâÀ» °¡Áö°í, ½ÉÇÏ¸é °öÃß°¡ µÇ´Â ±¸·çº´(rickets)ÀÌ ¹ß»ýÇÑ´Ù. ¼ºÀο¡¼ °¨¼Ò½Ã¿¡´Â »ÀÀÇ Ä®½·³óµµ°¡ °¨¼ÒÇÏ¿© »ý±â´Â °ñ¿¬ÈÁõ(osteomalacia)ÀÌ ¹ß»ýÇÑ´Ù. Ä¡·á´Â ºñŸ¹ÎÀÇ Åõ¿©ÀÌ´Ù. ºñŸ¹Î E(vitamin E) ÁַΠǪ¸¥ ÀÙÀ» °¡Áø ä¼Ò¿Í ±Í¸®(wheat germ)¿¡ ¸¹´Ù. »ê¼Ò¿¡ ´ëÇÑ µ¶¼ºÀ» °¨¼Ò½ÃŰ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ¾î, »ê¼Òµ¶¼ºÀ¸·Î ¹ß»ýµÇ´Â °ÍÀ¸·Î ÃßÁ¤µÇ´Â ¹Ì¼÷¾Æ¸Á¸·ÁõÀÇ ¿¹¹æ¿¡ »ç¿ëµÈ´Ù. ¶ÇÇÑ ºÎÁ·½Ã ¿ëÇ÷ÀÌ ÀϾÙ. ºñŸ¹Î K(vitamin K) °£¿¡¼ ¸¸µé¾îÁö´Â Ç÷¾×ÀÀ°í¹°ÁúÀÇ »ý¼º¿¡ ÇʼöÀûÀÌ´Ù. µû¶ó¼ ºÎÁ·½Ã Ç÷¾×ÀÀ°í°¡ ÀÌ·ç¾îÁöÁö ¾Ê¾Æ Á¶±×¸¸ »óó¿¡µµ ÃâÇ÷°æÇâÀ» º¸ÀδÙ. ÁÖ·Î °£, ä¼Ò±â¸§, ÀÙÀ» °¡Áø ä¼Ò µî¿¡ ¸¹´Ù. ´ë°³ ºÎÁ·Àº ½Å»ý¾Æ¿¡°Ô¼ ¸¹ÀÌ °üÂûµÈ´Ù. |
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| ¿µ¹® | rheumatoid factor | ÇÑ±Û | ·ù¸¶Æ¼½º ÀÎÀÚ |
|---|---|---|---|
| ¼³¸í | IgGÀÇ FcºÎÀ§¿¡ ÀÖ´Â Ç׿ø°áÁ¤ÀÎÀÚ¿¡ ´ëÇÑ Ç×ü·Î¼ ÀüÇüÀûÀÎ ¶Ç´Â È®½ÇÇÑ ·ù¸¶Æ¼½º°üÀý¿°(rheumatoid arthritis) ȯÀÚÀÇ 80%¿¡¼ ¹ß°ßµÈ´Ù. ·ù¸¶Æ¼½º ÀÎÀÚ´Â IgM, IgG, IgAÁß Çϳª°¡ µÉ ¼ö ÀÖÀ¸³ª ÁÖ·Î IgMÀÌ´Ù. ¼Ò¾Æ·ù¸¶Æ¼½º°üÀý¿°(juvenile rheumatoid arthritis: ¼Ò¾Æ±â¿¡ ¹ß»ýÇÏ´Â ·ù¸¶Æ¼½º°üÀý¿°)À» ºñ·ÔÇÑ, ´Ù¸¥ °áÇÕÁ¶Á÷º´À̳ª °¨¿°º´¿¡µµ ³ªÅ¸³¯ ¼ö ÀÖ´Ù |
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| ¿µ¹® | growth factor | ÇÑ±Û | ¼ºÀåÀÎÀÚ |
|---|---|---|---|
| ¼³¸í | ¼¼Æ÷ÀÇ ºÐÈ ¹× ¼ºÀå¿¡ °ü¿©ÇÏ´Â ´Ü¹éÁú. ¼ºÀåÀÎÀÚ´Â Á¤»ó ¼¼Æ÷Áֱ⿡ ÇʼöÀûÀ̱⠶§¹®¿¡ µ¿¹°ÀÇ »ý¸í¿¡ Áß´ëÇÑ ¿ä¼Ò°¡ µÈ´Ù. ¹«¾ùº¸´Ùµµ ¼ºÀåÀÎÀڴ žÆÀÇ ¹ßÀ°À» Á¶Á¤Çϰí Á¶Á÷ÀÇ À¯Áö ¹× º¸¼ö¿¡ Áß´ëÇÑ ¿ªÇÒÀ» Çϸç, Ç÷±¸ÀÇ »ý¼ºÀ» ÀÚ±ØÇÑ´Ù. ¶ÇÇÑ ¾ÏÀÇ ÁøÇà°úÁ¤¿¡µµ °ü¿©ÇÑ´Ù. |
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| ¿µ¹® | risk factor | ÇÑ±Û | À§ÇèÀÎÀÚ |
|---|---|---|---|
| ¼³¸í | ±¹Á¦¹æ»ç¼±¹æÈ£À§¿øÈ¸(ICRP)°¡ 1977³â ±Ç°í¿¡¼ ¹æ»ç¼±¹æÈ£ÀÇ ¸ñÀûÀ¸·Î äÅÃÇÑ Áö¼ö·Î, ´ÜÀ§¼±·®(1 Sv)´ç È®·üÀû ¿µÇâÀÇ ¹ß»ýÈ®·üÀ» ÃßÁ¤ÇÏ¿© ³ªÅ¸³½ °ÍÀÌ´Ù. »ý½Ä¼± ¼±·®¿¡ ´ëÇÑ À¯ÀüÀû¿µÇâÀÇ ¹ß»ý·ü(4¡¿10£3/Sv)À̳ª Àû»ö°ñ¼ö¼±·®¿¡ ´ëÇÑ ¹éÇ÷º´ ¹ß»ý·ü(2¡¿10£3/Sv)µî ¿Ü¿¡ »À, ÇãÆÄ, °©»ó»ù, Á¥»ù, ±âŸ Á¶Á÷ÀÇ À§ÇèÁö¼ö¸¦ ÃøÁ¤ÇÏ¿©, È®·üÀû ¿µÇâÀÇ Àü½Å¿¡ ÀÖ¾î¼ Ä¡»çÀ§ÇèÁö¼öÀÇ Çհ踦 16.5¡¿10£3/Sv·Î ÇÏ¿´´Ù. ±×ÈÄ ICRP´Â 1990³â ±Ç°í¿¡¼ ´ë»óÀÌ µÇ´Â Á¶Á÷°ú Àå±â¸¦ Ãß°¡Çϰí, ¼öÄ¡ °³Á¤À» ÇÏ¸é¼ ¸íεµ °¢¸ñÀûÈ®·üÁö¼ö¶ó°íÇÏ¿´´Ù. ÀÌ ±Ç°í¿¡ ÀÇÇϸé, Ä¡»çÀû È®·üÀû ¿µÇâÀÇ È®·üÁö¼öÀÇ ÇÕ°è´Â, ÀϹÝÀο¡ ÀÖ¾î 60.0¡¿10£3/SvÀÌ´Ù. |
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| UBBC | unsaturated vitamin B12 binding capacity |
|---|---|
| IFC | intermittent flow centrifugation; intrinsic factor concentrate |
| RIFC | rat intrinsic factor concentrate |
| CF | calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ... |
| ISA | Instrument Society of America; intracarotid sodium amytal; intrinsic simulating activity; intrinsic ... |
| UBBC | Unsaturated vitamin B12 binding capacity |
|---|---|
| VB12 | Vitamin B12 |
| IF | Intrinsic Factor |
| PC | Platelet concentrate |
| WPC | Whey protein concentrate |
| vitamin B12 with intrinsic factor concentrate | A combination of vitamin B12 with suitable preparations of the mucosa of the stomach or intestine of domestic animals used for food by humans. (05 Mar 2000) |
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| vitamin B12 | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
|---|---|
| vitamin B12 absorption test | <investigation> This test measures the amount of vitamin B12 in the urine after ingesting a dose of B12. This test evaluates vitamin B12 absorption. The cells in the stomach produce a substance known as intrinsic factor. This substance combines with B12 to allow absorption in the distal ileum. The patient is given a small dose of radioactive B12 which can then be detected in the patients urine. Pernicious anaemia is the clinical result of B12 deficiency. Conditions that can result in an abnormal Schilling test include: deficiency of intrinsic factor, malabsorption or the development of an antibody to intrinsic factor. The Schilling test can be performed with or without administration of intrinsic factor to determine what the underlying cause for pernicious anaemia. Laxative use, renal insufficiency and hypothyroidism can all interfere with the results of this test. (27 Sep 1997) |
| vitamin B12 deficiency | A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). (27 Sep 1997) |
| vitamin B12 neuropathy | A subacute or chronic disorder of the spinal cord, such as that occurring in certain patients with vitamin B12 deficiency, characterised by a slight to moderate degree of gliosis in association with spongiform degeneration of the posterior and lateral columns. Synonym: combined sclerosis, combined system disease, funicular myelitis, Putnam-Dana syndrome, vitamin B12 neuropathy. (05 Mar 2000) |
| cobalamin concentrate | The dried, partially purified product resulting from the growth of selected Streptomyces cultures or other cobalamin-producing microorganisms; contains at least 500 ug of cobalamin in each gram. (05 Mar 2000) |
| Castle's intrinsic factor | A mucoprotein normally secreted by the epithelium of the stomach and that binds vitamin B12, the intrinsic factor/B12 complex is selectively absorbed by the distal ileum, though only the vitamin is taken into the cell. (18 Nov 1997) |
| intrinsic factor | A mucoprotein normally secreted by the epithelium of the stomach and that binds vitamin B12, the intrinsic factor/B12 complex is selectively absorbed by the distal ileum, though only the vitamin is taken into the cell. (18 Nov 1997) |
| coenzyme B12 | <biochemistry> A coenzyme derived from cobalamine which is involved in carbon skeletal rearrangements. It is the only biomolecule known that has a carbon-metal bond. (09 Oct 1997) |
| pseudovitamin B12 | <biochemistry> Cobamide cyanide phosphate, 3'-ester with 7-alpha-d-ribofuranosyladenine, inner salt; vitamin B12 with adenine replacing dimethylbenzimidazole; one of several substances produced during anaerobic fermentation by certain organisms in bovine rumen contents; it is chemically closely similar to vitamin B12 (cyanocobalamin) but without, in humans, the physiologic action of the vitamin. (05 Mar 2000) |
| major intrinsic protein | <protein> Family of structurally related proteins with 6 transmembrane segments, associated with gap junctions or vacuoles. MIP is found in lens fibre gap junctions. Other members: nodulin 26 (soybean), tonoplast intrinsic protein (TIP) found in plant storage vacuoles, Drosophila neurogenic protein big brain. (18 Nov 1997) |
| positive-pressure respiration, intrinsic | Non-therapeutic positive end-expiratory pressure occurring frequently in patients with severe airway obstruction. It can appear with or without the administration of external positive end-expiratory pressure (positive-pressure respiration). It presents an important load on the inspiratory muscles which are operating at a mechanical disadvantage due to hyperinflation. Auto-peep may cause profound hypotension that should be treated by intravascular volume expansion, increasing the time for expiration, and/or changing from assist mode to intermittent mandatory ventilation mode. (12 Dec 1998) |
| intrinsic | Situated entirely within or pertaining exclusively to a part. Origin: L. Intrinsecus = situated on the inside (18 Nov 1997) |
| intrinsic asthma | <chest medicine> Bronchial asthma in which no extrinsic causes can be identified, and which is assumed to be due to an endogenous process, possibly allergic. (05 Mar 2000) |
| intrinsic colour | <dentistry> The addition of colour pigment within the material of a dental prosthesis. (05 Mar 2000) |
| intrinsic deflection | <physiology> With the electrode in direct contact with the muscle fibre, a rapid downward deflection from the peak of maximum positivity, signifying that the activation front has reached the subjacent muscle. (05 Mar 2000) |
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