| CDP | chondrodysplasia punctata; chronic destructive periodontitis; collagenase-digestible protein; contin... |
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| CSGBM | collagenase soluble glomerular basement membrane |
| HCI | Health Commons Institute; human collagenase inhibitor |
| HSC | Hand-Schuller-Christian [syndrome]; Health and Safety Commission; health sciences center; health scr... |
| IHSC | immunoreactive human skin collagenase |
| CDP | collagenase digestible protein |
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| vertebrate | <zoology> One of the Vertebrata. Source: Websters Dictionary (01 Mar 1998) |
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| vertebrate hormones | Hormones synthesised in vertebrates. (05 Mar 2000) |
| vertebrate viruses | Viruses infecting man and other vertebrates. (12 Dec 1998) |
| notochordal vertebrate | A lower vertebrate in which the notochord persists, unossified, in adult life. (05 Mar 2000) |
| microbial collagenase | <enzyme> A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -gly in the sequence -pro-xaa-gly-pro-. Six forms (or 2 classes) have been isolated from clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from bacillus cereus, empedobacter collagenolyticum, pseudomonas marinoglutinosa, and species of vibrio and streptomyces. Registry number: EC 3.4.24.3 (12 Dec 1998) |
| Clostridium histolyticum collagenase | <enzyme> An enzyme that catalyses the hydrolysis of collagen, preferentially at peptide bonds on the amino side of a glycylprolyl sequence. Synonym: clostridiopeptidase A, collagenase A, collagenase I. (05 Mar 2000) |
| collagenase | <enzyme> Proteolytic enzyme capable of breaking native collagen. Once the initial cleavage is made, less specific proteases will complete the degradation. Collagenases from mammalian cells are metallo enzymes and are collagen type specific. May be released in latent (proenzyme) form into tissues and require activation by other proteases before they will degrade fibrillar matrix. Bacterial collagenases are used in tissue disruption for cell harvesting. (18 Nov 1997) |
| collagenase A | <enzyme> An enzyme that catalyses the hydrolysis of collagen, preferentially at peptide bonds on the amino side of a glycylprolyl sequence. Synonym: clostridiopeptidase A, collagenase A, collagenase I. (05 Mar 2000) |
| neutrophil collagenase | <enzyme> Cleaves interstitial collagens in the triple helical domain; cleaves type I collagen more rapidly than type III; fibroblast collagenase cleaves at the same site as neutrophil colagenase Registry number: EC 3.4.24.34 Synonym: matrix metalloproteinase 8, mmp-8, mmp 8, fibroblast collagenase (26 Jun 1999) |
| vertebrate collagenase |
see under collagenase.
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