| variolation | <medicine> Inoculation with smallpox. Source: Websters Dictionary (01 Mar 1998) |
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| variolation |
deliberate inoculation with the virus of unmodified smallpox to produce immunity to the naturally occurring disease. As practiced in the Orient in ancient times, the dried crusts of smallpox lesions were applied to the skin or nasal mucous membranes, or were ingested. The method employed in Europe in the eighteenth century consisted in subcutaneous injection of material from the lesions. Variolation is now used only experimentally in animals.
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