| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| DV | dependent variable; diagnostic variable; difference in volume; digital vibration; dilute volume; dis... |
|---|---|
| VH | variable domain of heavy chain; variable heavy chain |
| VL | variable domain of the light chain; variable light chain |
| VNTR | variable number of tandem repeats; variable copy number tandem repeats |
| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
| CVID | Common Variable Immuno-Deficiency |
|---|---|
| CVH | Common variable hypogammaglobulinemia |
| CVI | Common variable immunodeficiency |
| HVR | Hyper-Variable Region |
| scFv | Single chain variable fragments |
| variable gene | <molecular biology> Those regions in the amino acid sequence of both the heavy and the light chains of immunoglobulins where there is considerable sequence variability from one immunoglobulin to other of the same class, in contrast to constant sequence (C) regions. The V regions are associated with the antigen binding areas. They contain hypervariable regions of particularly high sequence diversity. (18 Nov 1997) |
|---|
| variable | One of a battery of antigenicdeterminants expressed by a microorganismto elude immune detection. (09 Oct 1997) |
|---|---|
| variable antigen | <immunology> Term usually applied to the surface antigens of those parasitic or pathogenic organisms that can alter their antigenic character to evade host immune responses. (See antigenic variation). (18 Nov 1997) |
| variable deceleration | Transient foetal bradycardia usually denoting compression of the umbilical cord which may occur at any time in relation to a uterine contraction. (05 Mar 2000) |
| variable region | <molecular biology> Those regions in the amino acid sequence of both the heavy and the light chains of immunoglobulins where there is considerable sequence variability from one immunoglobulin to other of the same class, in contrast to constant sequence (C) regions. The V regions are associated with the antigen binding areas. They contain hypervariable regions of particularly high sequence diversity. (18 Nov 1997) |
| variable surface glycoprotein | <protein> One of a battery of antigenicdeterminants expressed by a microorganism to elude immune detection. (09 Oct 1997) |
| random variable | A variable that may assume a set of values, each with fixed probabilities or probability densities (its distribution), in such a way that the total probability assigned to the distribution is unity; the random variable may be discrete, continuous, or mixed discrete-continuous. (05 Mar 2000) |
| mixed discrete-continuous random variable | <statistics> A random variable that may assume some values with probabilities and others with probability densities. For example, in a 35-year-old man with familial polyposis of the colon, the distribution of time until malignant disease occurs consists of a probability that he already has cancer (which would be assigned the waiting time 0), a probability density of developing it in the future and a probability that he will die of some other cause before he develops cancer. (05 Mar 2000) |
| moderator variable | A variable that interacts by virtue of being antecedent or intermediate in the causal pathway. (05 Mar 2000) |
| common variable immunodeficiency | Heterogeneous group of immunodeficiency syndromes characterised by hypogammaglobulinaemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections. (12 Dec 1998) |
| condenser, variable-focus | <microscopy> Essentially an Abbe condenser in which the upper lens element is fixed and the lower movable. The lower lens may be used to focus the illumination between the elements so that it emerges from the stationary lens as a large diameter parallel bundle. The field of low-power objectives may thus be filled without removing the top element. at the opposite extreme it can be adjusted to have a numerical aperture as high as 1.3. See: illumination, critical. (05 Aug 1998) |
| continuous random variable | Continuous variable that may randomly assume any value in its domain but any particular value has no probability of occurring, only a probability density. (05 Mar 2000) |
| continuous variable | A variable that may take on any value in an interval or intervals (its domain). (05 Mar 2000) |
| dependent variable | In experiments, a variable that is influenced by or dependent upon changes in the independent variable; e.g., the amount of a written passage retained (dependent variable) as a function of the different numbers of minutes (independent variable) allowed to study the passage. (05 Mar 2000) |
| discrete random variable | A random variable that may assume a countable number of values, each with a probability strictly greater than zero. (05 Mar 2000) |
| discrete variable | A variable that may assume only a countable (usually finite) number of values. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|