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UD ulcerative dermatosis; ulnar deviation; undetermined; underdeveloped; unit dose; urethral dilatation...
UPG uroporphyrinogen
UPS ultraviolet photoelectron spectroscopy; uninterruptible power supply; uroporphyrinogen synthetase; u...
URO urology; uroporphyrin; uroporphyrinogen; utilization review organization
UROD uroporphyrinogen decarboxylase
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URO-D Uroporphyrinogen decarboxylase
URO-III-S uroporphyrinogen III synthase
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uroporphyrinogen See: porphyrinogens.
Uroporphyrinogen decarboxylase, an enzyme that participates in haem biosynthesis; it catalyses the decarboxylation of uroporphyrinogen III to produce coproporphyrinogen III; it also acts on uroporphyrinogen I; a deficiency of this enzyme will result in either porphyria cutanea tarda or hepatoerythropoietic porphyria.
Uroporphyrinogen III cosynthase, an enzyme in haem biosynthesis that participates in the formation of uroporphyrinogen III; a deficiency of this protein results in congenital erythropoietic porphyria.
(05 Mar 2000)
uroporphyrinogen decarboxylase <enzyme> One of the enzymes active in haem biosynthesis. It catalyses the decarboxylation of uroporphyrinogen III to coproporphyrinogen III by the conversion of four acetic acid groups to four methyl groups.
Chemical name: Uroporphyrinogen-III carboxy-lyase
Registry number: EC 4.1.1.37
(12 Dec 1998)
uroporphyrinogen I synthetase <enzyme> An enzyme of haem biosynthesis that is defective in the inherited (autosomal dominant) disease, acute intermittent porphyria. UP I is isomerised to UP III by UP III synthetase, defective in the autosomal recessive disease, congenital erythropoietic porphyria.
(18 Nov 1997)
uroporphyrinogen-III synthase <enzyme> An enzyme that catalyses the cyclization of hydroxymethylbilane to yield uroporphyrinogen III and water.
Chemical name: Hydroxymethylbilane hydro-lyase (cyclizing)
Registry number: EC 4.2.1.75
(12 Dec 1998)
uroporphyrinogens Porphyrinogens which are intermediates in haem biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 3 ÆäÀÌÁö: 1
  • Uroporphyrinogen Decarboxylase - »õâ An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.
    Synonyms : Uroporphyrinogen III Decarboxylase, Carboxy-Lyase, Uroporphyrinogen, Decarboxylase, Uroporphyrinogen, Decarboxylase, Uroporphyrinogen III, Uroporphyrinogen Carboxy Lyase
  • Uroporphyrinogen III Synthetase - »õâ An enzyme that catalyzes the cyclization of hydroxymethylbilane to yield UROPORPHYRINOGEN III and water. It is the fourth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by UROS gene. Mutations of UROS gene result in CONGENITAL ERYTHROPOIETIC PORPHYRIA.
    Synonyms : Cosynthetase, Uroporphyrinogen III, Isomerase, Uroporphyrinogen, Synthase, Uroporphyrinogen-III, Synthetase, Uroporphyrinogen III, Uroporphyrinogen III Synthase
  • Uroporphyrinogens - »õâ Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
    Synonyms : Uroporphyrinogen III
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uroporphyrinogen a porphyrinogen (q.v.) in which each pyrrole ring has one acetate side chain and one propionate side chain; it is formed by condensation of four molecules of porphobilinogen. Four isomers are possible but only two exist naturally, types I and III; the latter is a functional intermediate in heme biosynthesis while the former is produced in an abortive side reaction.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
uroporphyrinogen decarboxylase [EC 4.1.1.37] an enzyme of the lyase class that catalyzes the decarboxylation of uroporphyrinogen III to coproporphyrinogen III in the biosynthesis of heme. Decreased enzyme activity is associated with porphyria cutanea tarda and the variant hepatoerythropoietic porphyria.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
uroporphyrinogen I synthase hydroxymethylbilane synthase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
uroporphyrinogen III cosynthase uroporphyrinogen-III synthase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
uroporphyrinogen-III synthase [EC 4.2.1.75] an enzyme of the lyase class that acts concertedly with hydroxymethylbilane synthase to convert porphobilinogen to uroporphyrinogen III in the biosynthesis of porphyrins and heme. Deficiency of the enzyme, an autosomal recessive trait, causes congenital erythropoietic porphyria. Called also uroporphyrinogen III cosynthase.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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