| HPRT | hypoxanthine-guanine phosphoribosyltransferase |
|---|---|
| OPRT | orotate phosphoribosyltransferase |
| OPRTase | orotate phosphoribosyltransferase |
| PTU | Prophyl-Thio-Uracil |
| AHU | acute hemolytic uremic [syndrome]; arginine, hypoxanthine, and uracil |
| UPRT | Uracil phosphoribosyltransferase |
|---|---|
| UPRTase | Uracil phosphoribosyltransferase |
| APRT | Adenine phosphoribosyltransferase |
| HPRT | Hypoxanthine guanine phosphoribosyltransferase |
| hprt | Hypoxanthine phosphoribosyltransferase gene |
| uracil phosphoribosyltransferase | See: phosphoribosyltransferase. (05 Mar 2000) |
|---|
| uracil | <biochemistry> The pyrimidine base from which uridine is derived. (18 Nov 1997) |
|---|---|
| uracil-6-carboxylic acid | Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate). (18 Nov 1997) |
| uracil dehydrogenase | An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine. Synonym: uracil oxidase. (05 Mar 2000) |
| uracil-DNA glycosidase | <enzyme> Catalyses hydrolysis of n-glycosidic bond of damaged nucleotide residues to give free uracil and partly depyrimidinated DNA of unaltered chain length; does not cleave phosphodiester bonds; a DNA repair enzyme Registry number: EC 3.2.2.- Synonym: ura-DNA glycosidase, uracil-DNA glycosylase, uracil n-glycosidase, ura-DNA glycosylase, uracil n-glycosylase (26 Jun 1999) |
| uracil mustard | <chemical> Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage. Pharmacological action: antineoplastic agent, alkylating. Chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)- (12 Dec 1998) |
| uracil oxidase | An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine. Synonym: uracil oxidase. (05 Mar 2000) |
| uracil permease | <chemical> Mediates uptake of uracil in eucaryotic organisms; does not transport other natural pyrimidines such as cytosine, thymine or uridine Chemical name: permease, uracil Synonym: n 137 (26 Jun 1999) |
| adenine phosphoribosyltransferase | <enzyme> An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into nucleic acids. Chemical name: AMP:pyrophosphate phospho-D-ribosyltransferase Registry number: EC 2.4.2.7 (12 Dec 1998) |
| aminoglycoside phosphoribosyltransferase | <enzyme> Coded by neo-gene; involved in kanamycin resistance; no other information given on reaction 8/93 Registry number: EC 2.4.2.- Synonym: aminoglycosidephosphoribosyltransferase (26 Jun 1999) |
| anthranilate phosphoribosyltransferase | <enzyme> An enzyme that catalyses the formation of n-5'-phosphoribosylanthranilic acid from anthranilate and phosphoribosylpyrophosphate, the first step in tryptophan synthesis in e. Coli. It exists in a complex with anthranilate synthase in bacteria. Chemical name: N-(5-Phospho-D-ribosyl)-anthranilate:pyrophosphate phospho-alpha-D-ribosyltransferase Registry number: EC 2.4.2.18 (12 Dec 1998) |
| ATP phosphoribosyltransferase | <enzyme> An enzyme that catalyses the first step of the pathway for histidine biosynthesis in salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield n-1-(5'-phosphoribosyl)-ATP and pyrophosphate. Chemical name: 1-(5-Phospho-D-ribosyl)-ATP:pyrophosphate phospho-alpha-D- ribosyltransferase Registry number: EC 2.4.2.17 (12 Dec 1998) |
| phosphoribosyltransferase | One of a group of enzymes (EC sub-subclass 2.4.2, pentosyltransferases) that transfers d-ribose 5-phosphate from 5-phospho-alpha-d-ribosyl pyrophosphate to a purine, pyrimidine, or pyridine acceptor, forming a 5'-nucleotide and inorganic pyrophosphate, or d-ribose from d-ribosyl phosphate to a base, forming a nucleoside, or similar pentose transfers; important in nucleotide biosynthesis. Specific phosphoribosyltransferases are preceded by the name of the acceptor base, e.g., uracil phosphoribosyltransferase (i.e., uracil + PRPP &dblarr; UMP + pyrophosphate). (05 Mar 2000) |
| purine phosphoribosyltransferase | <enzyme> Specific purine phosphoribosyltransferases are EC 2.4.2.7 and 2.4.2.8. Registry number: EC 2.4.2.- (26 Jun 1999) |
| pyrimidine phosphoribosyltransferase | <enzyme> Pyrimidine monophosphate and pyrophosphate gives pyrimidine and phosphoribosyl pyrophosphate; acts with uracil, orotic acid or fluorouracil Registry number: EC 2.4.2.- (26 Jun 1999) |
| hypoxanthine guanine phosphoribosyltransferase | <enzyme> An enzyme that catalyses the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the lesch-nyhan syndrome, while partial deficiency results in overproduction of uric acid. Chemical name: IMP:pyrophosphate phospho-D-ribosyltransferase Registry number: EC 2.4.2.8 (12 Dec 1998) |
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