| TYRL | tyrosinase-like |
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| TYR: | TYROSINASE |
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| TRP-1 | Tyrosinase Related Protein-1 |
| TRP | Tyrosinase related protein |
| TRP-2 | Tyrosinase-related protein 2 |
| tyrosinase | <enzyme> A copper containing protein (a monoxygenase) that catalyses the oxidation of tyrosine and sets in train spontaneous reactions that yield melanin, the black pigment of skin, hair and eyes. The first intermediate is 3, 4 dihydroxyphenylalanine (DOPA). Lack of tyrosinase activity is responsible for albinism. (18 Nov 1997) |
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| beta-tyrosinase | <enzyme> An enzyme that catalyses the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from d-tyrosine, l-cysteine, s-methyl-l-cysteine, l-serine, and d-serine, although at a slower rate. Chemical name: L-Tyrosine phenol-lyase (deaminating) Registry number: EC 4.1.99.2 (12 Dec 1998) |
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| tyrosinase |
Tyrosinase is required for melanin biosynthesis, and the expression of its gene leads to pigment production, and is therefore used as a coat-colour marker.
Ãâó: www.nature.com/nrg/journal/v2/n10/glossary/nrg1001...
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| tyrosinase-negative (ty-neg) oculocutaneous a. |
a recessive disorder characterized by absence of pigment in hair, skin, and eyes. Signs include white hair throughout life, skin that is pink and highly susceptible to neoplasias, absence of pigmented nevi or freckles, gray to blue eyes, prominent red reflexes from the fundi, severe nystagmus, photophobia, and reduced visual acuity (most patients are legally blind). Called also albinism, a. I, and complete perfect a.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| tyrosinase-positive (ty-pos) oculocutaneous a. |
a recessive disorder characterized by reduced, but usually visible, pigmentation in hair, skin, and eyes, which varies with race and age. Onset of pigment formation is delayed, pigment accumulates with age, and intensity of accumulation depends on race; hence all ty-pos infants resemble ty-neg infants, and ty-pos adult Blacks may be darker than normal blond Caucasians. The presence of pigmented nevi distinguishes ty-pos and ty-neg Caucasians. Called also a. II, albinoidism, and complete imperfect a.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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