| tuftsin | <chemical> N(2)-(1-(n(2)-l-threonyl)-l-lysyl)-l-prolyl)-l-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the fd fragment of the gamma-globulin molecule. Chemical name: L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)- (12 Dec 1998) |
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Synonyms : L-Thr-L-Lys-L-Pro-L-Arg, L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine, Taftsin
| tuftsin |
a tetrapeptide (Thr-Lys-Pro-Arg) cleaved from IgG that stimulates phagocytosis by neutrophils. It is produced primarily in the spleen; hereditary tuftsin deficiency and tuftsin deficiency following splenectomy result in increased susceptibility to certain infections.
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