| tc | transcutaneous; translational control |
|---|---|
| tcRNA | translational control ribonucleic acid |
| TI | inversion time; temporal integration; terminal ileum; thalassemia intermedia; therapeutic index; tho... |
| amp | ampere; amplification; ampule; amputation, amputee |
| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
| 'RACE' | 3' rapid amplification of cDNA ends |
|---|---|
| 3' RACE | 3' rapid amplification of cDNA ends |
| 5' RACE | Rapid amplification of cDNA ends |
| ASA | Allele Specific Amplification |
| ARMS | Amplification Refractory Mutation System |
| post-translational modification | The enzymatic processing of a polypeptide chain after translation from messenger RNA and after peptide bond formation has occurred. Examples include glycosylation, acylation, limited proteolysis, phosphorylation, isoprenylation. (10 Oct 1997) |
|---|---|
| protein processing, post-translational | Any of various enzymically catalyzed post-translational modifications of peptides or proteins in the cell of origin. These modifications include carboxylation, hydroxylation, acetylation, phosphorylation, methylation, glycosylation, oxidation-reduction, degradation and lysis, peptide bond formation, and changes in molecular weight and electrophoretic motility. (12 Dec 1998) |
| translational control | <molecular biology> The control of protein synthesis by regulation of the translation step, for example by selective usage of preformed mRNA or instability of the mRNA. (18 Nov 1997) |
| translational repressor | A molecule that blocks translation by binding to a messenger RNA. (09 Oct 1997) |
| amplification | <molecular biology> An increase in the number of copies of a specific DNA fragment, can be in vivo or in vitro. See: cloning, polymerase chain reaction. (09 Oct 1997) |
| random amplification of polymorphic DNA | <molecular biology> A term originally invented by polymer chemists to describe a disordered tangle of a linear polymer chain with curved sections. In DNA parlance the random coil refers to the structure that results from melting or other forms of separation of the double helix, i.e. Helix coil transition. (18 Nov 1997) |
| gene amplification | <molecular biology> Selective replication of DNA sequence within a cell, producing multiple extra copies of that sequence. The best known example occurs during the maturation of the oocyte of Xenopus, where the set (normally 500 copies) of ribosomal RNA genes is replicated some 4,000 times to give about 2 million copies. (18 Nov 1997) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| DNA amplification | <molecular biology> The use of enzymes in making millions or billions of copies of a single DNA sequence (see PCR). (14 Nov 1997) |
| ligase amplification reaction | <molecular biology> Method for detecting small quantities of a target DNA, with utility similar to PCR. It relies on DNA ligase to join adjacent synthetic oligonucleotides after they have bound the target DNA. Their small size means that they are destabilised by single base mismatches and so form a sensitive test for the presence of mutations in the target sequence. (18 Nov 1997) |
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