| ¿µ¹® | mutation | ÇÑ±Û | µ¹¿¬º¯ÀÌ |
|---|---|---|---|
| ¼³¸í | ¼¼Æ÷ÀÇ dna ÀÚüÀÇ º¯ÀÌ¿¡ ÀÇÇØ ÀϾ´Â ¼¼Æ÷º¯À̸¦ ¸»ÇÑ´Ù. ÀÌ·¯ÇÑ °æ¿ì µ¹¿¬º¯ÀÌ·Î ÀÏ¾î³ ¼¼Æ÷´Â ±× ÀÌÈÄ µþ¼¼Æ÷(daughter cell)¿¡¼µµ ±× º¯À̰¡ ¿©ÀüÈ÷ À¯ÁöµÇ¹Ç·Î Á¾(species)ÀÇ º¯È³ª, ȤÀº ¼¼Æ÷ÀÇ ¾Ç¼ºº¯È¯(malignant transformation)¿¡ °ü¿©ÇÑ´Ù. |
||
| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| ATN | acute tubular necrosis; augmented transition network |
| DOUBTFUL | double quantum transition for finding unresolved lines |
| ARMS | Amplification Refractory Mutation System |
|---|---|
| MFD | Mutation frequency decline |
| RIP | Repeat Induced Point mutation |
| RSM | Restriction Site Mutation |
| SMART | Somatic Mutation And Recombination Test |
| transition mutation | A point mutation involving substitution of one base-pair for another, i.e., replacement of one purine for another and of one pyrimidine for another pyrimidine without change in the purine-pyrimidine orientation. (05 Mar 2000) |
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| cervicothoracic transition | The junction between the last cervical vertebra and first thoracic vertebra. (05 Mar 2000) |
|---|---|
| health transition | Demographic and epidemiologic changes that have occurred in the last five decades in many developing countries and that are characterised by major growth in the number and proportion of middle-aged and elderly persons and in the frequency of the diseases that occur in these age groups. The health transition is the result of efforts to improve maternal and child health via primary care and outreach services and such efforts have been responsible for a decrease in the birth rate; reduced maternal mortality; improved preventive services; reduced infant mortality, and the increased life expectancy that defines the transition. (12 Dec 1998) |
| helix-coil transition | <molecular biology> A change in the structure of a nucleic acid or protein molecule from a highly ordered, complex structure to a random, chaotic structure. Also means that the protein or nucleic acid becomes denatured. (09 Oct 1997) |
| isomeric transition | The transition of a nuclear isomer to a lower quantum state; e.g., 131mXe → 131Xe + g. (05 Mar 2000) |
| transition | 1. Passage from one place or state to another; charge; as, the transition of the weather from hot to cold. "There is no death, what seems so is transition." (Longfellow) 2. A direct or indirect passing from one key to another; a modulation. 3. A passing from one subject to another. "[He] with transition sweet, new speech resumes." (Milton) 4. <biology> Change from one form to another. This word is sometimes pronounced; but according to Walker, Smart, and most other authorities, the customary and preferable pronunciation is, although this latter mode violates analogy. Other authorities say . <geology> Transition rocks, a term formerly applied to the lowest uncrystalline stratified rocks (graywacke) supposed to contain no fossils, and so called because thought to have been formed when the earth was passing from an uninhabitable to a habitable state. Origin: L. Transitio: cf. F. Transition. See Transient. Source: Websters Dictionary (01 Mar 1998) |
| transition electron | An electron that moves from one energy level to another to fill a vacancy in a shell, with the emission of characteristic radiation. (05 Mar 2000) |
| transition probability model | A model to account for the apparently random variation in cell cycle time between individual animal tissue cells in culture that postulates that transition from G1 to s phase is probabilistic. Contrasts with hypotheses that require the accumulation of critical levels of particular proteins. (18 Nov 1997) |
| transition protein | <molecular biology> In spermatogenesis, group of proteins that displace histones from nuclear DNA and that are in turn displaced by protamines to produce the transcriptionally inactive nuclear DNA characteristic of the sperm nucleus. (18 Nov 1997) |
| transition state | The activated state of a molecule that has partly undergone a chemicalreaction. (09 Oct 1997) |
| transition state intermediate | In a chemical reaction, an unstable and high-energy configuration assumed by reactants on the way to making products. Enzymes are thought to bindand stabilise the transition state, thus lowering the energy of activation needed to drive the reaction to completion. (09 Oct 1997) |
| transition temperature | <chemistry> The temperature at which there is a transition in the organisation of, for example: the phospholipids of a membrane where the transition temperature marks the shift from fluid to more crystalline. Usually determined by using an Arrhenius plot of activity against the reciprocal of absolute temperature, the transition temperature being that temperature at which there is an abrupt change in the slope of the plot. In membranes such phase transitions tend to be inhibited by the presence of cholesterol. (18 Nov 1997) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| transition mutation |
A mutation in which a purine/pyrimidine base pair is replaced with a base pair in the same purine/pyrimidine relationship eg. GC with AT.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/tuvwxyz.htm
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