| EDIM | epizootic diarrhea of infant mice |
|---|---|
| MVM | microvillose membrane; minute virus of mice |
| PFC | pair-fed control [mice]; patient-focused care; pelvic flexion contracture; perfluorocarbon; pericard... |
| PVM | pneumonia virus of mice; proteins, vitamins, and minerals |
| NTG | Non-transgenic |
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| Non-Tg | Non-transgenic |
| Tg | TCR)-transgenic |
| TG | Transgenic |
| TGR | transgenic rat |
| transgenic mice | Mice that have a piece of foreign lincor DNA integrated into their genome. (05 Mar 2000) |
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| mice, transgenic | Laboratory mice that have been produced from a genetically manipulated egg or embryo. The technique involves microinjection of foreign DNA fragments into the nucleus of the fertilised egg and transferring it into the uterus of a foster mother mouse. The inserted gene becomes integrated into every cell and tissue of the developing mouse, including its germ line cells. (12 Dec 1998) |
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| animals, transgenic | Animals, or the offspring of such animals, into which cloned genetic material has been experimentally transferred by microinjection of foreign DNA, either directly or into embryos or differentiated cell types. Transgenic rabbits, mice, fish, xenopus, sheep, pigs, and chickens have been produced using genes of sea urchins, candida, drosophila, and mice. (12 Dec 1998) |
| plants, transgenic | Plants into which genetic material from another species has been transferred. The technique most frequently applied makes use of a natural plant-directed gene vector, the gram-negative soil bacterium agrobacterium tumefaciens. A second system more analogous to those used for transforming mammalian cell lines is the direct transfer of DNA into plant protoplasts, for example by electroporation or polyethylene glycol treatment. (12 Dec 1998) |
| transgenic | <molecular biology> This term describes an organism that has had genes from another organism put into its genome through recombinant DNA techniques. Origin: Gr. Gennan = to produce (09 Oct 1997) |
| transgenic animal | Genetically engineered animalor offspring of genetically engineeredanimals. The transgenic animal usually contains material from at leaseone unrelated organism, such as from a virus, plant, or other animal. (09 Oct 1997) |
| transgenic disease models | Animals that have been created to acquire particular human diseases. (14 Nov 1997) |
| transgenic organism | <molecular biology> Organisms that have integrated foreign DNA into their germ line as a result of the experimental introduction of DNA. Recombinant DNA techniques are commonly used to produce a transgenic organism. (13 Nov 1997) |
| transgenic plant | Genetically engineered plantor offspring of genetically engineered plants. The transgenic plant usually contains material from at least one unrelated organisms, such as from a virus, animal, or other plant. (09 Oct 1997) |
| biozzi mice | <immunology> Any genetic line of mice which has been bred to have unusually high or unusually low antibody responses to various antigens. (19 Jan 1998) |
| mammary cancer virus of mice | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| mammary tumour virus of mice | Member of the retrovirus subfamily Oncornavirinae, antigenically distinct from the murine leukaemia-sarcoma complex, that is associated with adenocarcinomatous tumours of the mammary gland, commonly latent in wild and laboratory mice and causing cancer only in genetically susceptible strains under certain hormonal influences. Synonym: Bittner agent, Bittner virus, Bittner's milk factor, mammary cancer virus of mice, milk factor, mouse mammary tumour virus. (05 Mar 2000) |
| mice | The common name for the species mus musculus. (12 Dec 1998) |
| mice, inbred cftr | A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the cftr (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands. (12 Dec 1998) |
| mice, inbred hrs | Homozygous, permanently near-hairless mice which lose their hair at about 10 days of age. (12 Dec 1998) |
| mice, inbred mdx | A strain of mice arising from a spontaneous mutation (mdx) in inbred c57bl mice. This mutation is x chromosome-linked and produces viable homozygous animals that lack the muscle protein dystrophin, have high serum levels of muscle enzymes, and possess histological lesions similar to human muscular dystrophy. The histological features, linkage, and map position of mdx make these mice a worthy animal model of duchenne muscular dystrophy. (12 Dec 1998) |
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