| AAALAC | American Association for Accreditation of Laboratory Animal Care |
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| AALAS | American Association of Laboratory Animal Science |
| ACP | accessory conduction pathway; acid phosphatase; acyl carrier protein; American College of Pathologis... |
| AHI | active hostility index; Animal Health Institute; apnea-plus-hypopnea index |
| AMC | academic medical center; acetylmethyl carbinol; Animal Medical Center; antibody-mediated cytotoxicit... |
| A | Animal |
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| LAA | Laboratory Animal Allergy |
| NAHMS | National Animal Health Monitoring System |
| NTG | Non-transgenic |
| Non-Tg | Non-transgenic |
| transgenic animal | Genetically engineered animalor offspring of genetically engineeredanimals. The transgenic animal usually contains material from at leaseone unrelated organism, such as from a virus, plant, or other animal. (09 Oct 1997) |
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| animals, transgenic | Animals, or the offspring of such animals, into which cloned genetic material has been experimentally transferred by microinjection of foreign DNA, either directly or into embryos or differentiated cell types. Transgenic rabbits, mice, fish, xenopus, sheep, pigs, and chickens have been produced using genes of sea urchins, candida, drosophila, and mice. (12 Dec 1998) |
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| mice, transgenic | Laboratory mice that have been produced from a genetically manipulated egg or embryo. The technique involves microinjection of foreign DNA fragments into the nucleus of the fertilised egg and transferring it into the uterus of a foster mother mouse. The inserted gene becomes integrated into every cell and tissue of the developing mouse, including its germ line cells. (12 Dec 1998) |
| plants, transgenic | Plants into which genetic material from another species has been transferred. The technique most frequently applied makes use of a natural plant-directed gene vector, the gram-negative soil bacterium agrobacterium tumefaciens. A second system more analogous to those used for transforming mammalian cell lines is the direct transfer of DNA into plant protoplasts, for example by electroporation or polyethylene glycol treatment. (12 Dec 1998) |
| transgenic | <molecular biology> This term describes an organism that has had genes from another organism put into its genome through recombinant DNA techniques. Origin: Gr. Gennan = to produce (09 Oct 1997) |
| transgenic disease models | Animals that have been created to acquire particular human diseases. (14 Nov 1997) |
| transgenic mice | Mice that have a piece of foreign lincor DNA integrated into their genome. (05 Mar 2000) |
| transgenic organism | <molecular biology> Organisms that have integrated foreign DNA into their germ line as a result of the experimental introduction of DNA. Recombinant DNA techniques are commonly used to produce a transgenic organism. (13 Nov 1997) |
| transgenic plant | Genetically engineered plantor offspring of genetically engineered plants. The transgenic plant usually contains material from at least one unrelated organisms, such as from a virus, animal, or other plant. (09 Oct 1997) |
| animal | 1. An organised living being endowed with sensation and the power of voluntary motion, and also characterised by taking its food into an internal cavity or stomach for digestion; by giving carbonic acid to the air and taking oxygen in the process of respiration; and by increasing in motive power or active aggressive force with progress to maturity. 2. One of the lower animals; a brute or beast, as distinguished from man; as, men and animals. Origin: L, fr. Anima breath, soul: cf. F. Animal. See Animate. 1. Of or relating to animals; as, animal functions. 2. Pertaining to the merely sentient part of a creature, as distinguished from the intellectual, rational, or spiritual part; as, the animal passions or appetites. 3. Consisting of the flesh of animals; as, animal food. Animal magnetism. See Magnetism and Mesmerism. Animal electricity, the electricity developed in some animals, as the electric eel, torpedo, etc. <physiology> Animal flower, the heat generated in the body of a living animal, by means of which the animal is kept at nearly a uniform temperature. Animal spirits. See Spirit. Animal kingdom, the whole class of beings endowed with animal life. It embraces several subkingdoms, and under these there are Classes, Orders, Families, Genera, Species, and sometimes intermediate groupings, all in regular subordination, but variously arranged by different writers. The following are the grand divisions, or subkingdoms, and the principal classes under them, generally recognised at the present time: - Vertebrata, including Mammalia or Mammals, Aves or Birds, Reptilia, Amphibia, Pisces or Fishes, Marsipobranchiata (Craniota); and Leptocardia (Acrania). Tunicata, including the Thaliacea, and Ascidioidea or Ascidians. Articulata or Annulosa, including Insecta, Myriapoda, Malacapoda, Arachnida, Pycnogonida, Merostomata, Crustacea (Arthropoda); and Annelida, Gehyrea (Anarthropoda). Helminthes or Vermes, including Rotifera, Chaetognatha, Nematoidea, Acanthocephala, Nemertina, Turbellaria, Trematoda, Cestoidea, Mesozea. Molluscoidea, including Brachiopoda and Bryozoa. Mollusca, including Cephalopoda, Gastropoda, Pteropoda, Scaphopoda, Lamellibranchiata or Acephala. Echinodermata, including Holothurioidea, Echinoidea, Asterioidea, Ophiuroidea, and Crinoidea. Coelenterata, including Anthozoa or Polyps, Ctenophora, and Hydrozoa or Acalephs. Spongiozoa or Porifera, including the sponges. Protozoa, including Infusoria and Rhizopoda. For definitions, see these names in the Vocabulary. Origin: Cf. F. Animal. Source: Websters Dictionary (01 Mar 1998) |
| animal black | Charcoal produced by incomplete combustion of animal tissues, especially bone. Synonym: animal black, bone black, bone charcoal. (05 Mar 2000) |
| animal cell culture | <cell culture> Mammalian cells are fragile and harder to grow than other cell types, but their large-scale culturing is an economic boon because it allows for the production of proteins that are otherwise difficult or expensive or unethical to extract from living organisms. The cells are immobilised on a substrate and then perfused with culture medium, The cells are in a free suspension which is very gently mixed and aerated. (12 Nov 1997) |
| animal cell immobilisation | <cell culture> Animal cells are widely used in biotechnology to produce genetically engineered proteins. However, they are more fragile than bacterial cells, and immobilising the cell facilitates the fermentation process. Many animal cells stick down flat on a suitable surface, hugging it as they would hug other cells or connective matrices in the body. If grown on suitable plastic surfaces, on glass or many ceramics, these cells will stick to them. In this way, they are easier to grow. (14 Nov 1997) |
| animal charcoal | Charcoal produced by incomplete combustion of animal tissues, especially bone. Synonym: animal black, bone black, bone charcoal. (05 Mar 2000) |
| animal communication | Communication between animals involving the giving off by one individual of some chemical or physical signal, that, on being received by another, influences its behaviour. (12 Dec 1998) |
| animal dander | <immunology, zoology> The epidermis (skin) from an animal that can elicit an allergic response. (12 Nov 1997) |
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