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  • transforming growth factor
    전환성장인자
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  • transforming growth factor
    전환성장인자
  • transforming substance
    형질전환유효물질
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  • TGF => transforming growth factor
    전환성장인자
  • acute transforming virus
    급성 형질전환 바이러스
  • acute transforming virus
    급성형질전환바이러스
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  • transforming growth factor
    전환성장인자
  • transforming principle
    형질전환 유효인자
  • transforming substance
    형질전환 유효물질
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  • acute transforming virus
    급성 형질전환 바이러스
  • acute transforming virus
    급성형질전환바이러스
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  • transforming growth factor
    전환성장인자
    轉換成長因子
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  • transforming growth factor
    변형 성장 인자(變形成長 因子)
  • transforming principle
    형질전환소( 形質轉換素)
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TGF Transforming Growth Factor
LTF lactotransferrin; lipotropic factor; lymphocyte-transforming factor
TGF T-cell growth factor; transforming growth factor; tuboglomerular feedback; tumor growth factor
TG-F transforming growth factor
TGFA transforming growth factor alpha; triglyceride fatty acid
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TGF Anti-transforming growth factor
TGF-beta Anti-transforming growth factor-beta
h-TGF alpha Human transforming growth factor-alpha
PTTG Pituitary tumor transforming gene
rhTGF-beta 1 Recombinant human transforming growth factor-beta 1
CancerWEB 영영 의학사전 맞춤 검색 결과 : 9 페이지: 1
transforming agent A substance which is able to induce mitosis of certain eukaryotic cells.
(09 Oct 1997)
transforming factor The DNA responsible for bacterial transformation.
(05 Mar 2000)
transforming gene <molecular biology> Genes, originally of tumour viruses, responsible for their ability to transform cells. The term now serves as an operational definition of oncogenes.
(18 Nov 1997)
transforming growth factor <growth factor> Proteins secreted by transformed cells that can stimulate growth of normal cells.
Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform.
Transforming growth factor alpha, 50 amino acid polypeptide originally isolated from viral transformed rodent cells, contains EGF like domain and binds to EGF receptor. Stimulates growth of microvascular endothelial cells, i.e. Is angiogenic.
Transforming growth factor beta a homodimer of two 112 chains, polypeptide is secreted by many different cell types, stimulates wound healing but in vitro is also a growth inhibitor for certain cell types. The transforming growth factor family includes many of the bone morphogenetic proteins.
Acronym: TGF
(18 Nov 1997)
transforming growth factor alpha Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown.
(12 Dec 1998)
transforming growth factor beta Factor synthesised in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with tgf-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. Tgf-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of tgf-beta: tgf-beta1, tgf-beta2, and tgf-beta1.2. The latter is a heterodimer made up of both tgf-beta1 and tgf-beta2.
(12 Dec 1998)
transforming growth factors <chemical> Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumour-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, transforming growth factor alpha and transforming growth factor beta.
Chemical name: Animal growth regulators, transforming growth factors
(12 Dec 1998)
transforming oncogene <molecular biology> A gene that upon transfection converts a previously immortalised cell to the malignant phenotype.
(09 Oct 1997)
transforming virus <molecular biology, virology> Viruses capable of inducing malignant transformation of animal cells in culture. Among the Oncovirinae, nondefective viruses that lack oncogenes can induce tumours such as leukaemias in animals, but cannot transform in vitro. On acquisition of oncogenes they become (acute) transforming viruses.
(18 Nov 1997)
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antigens, polyomavirus transforming Polyomavirus antigens which cause infection and cellular transformation. The large t antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle t antigen for the transformation of primary cells. Small t antigen is necessary for the completion of the productive infection cycle.
(12 Dec 1998)
receptors, transforming growth factor beta Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behaviour of cells. Two types of transforming growth factor receptors have been recognised. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action. Transforming growth factor alpha binds to the same receptors as epidermal growth factor (see receptors, epidermal growth factor-urogastrone).
(12 Dec 1998)
pro-transforming growth factor-alpha processing protease <enzyme> Converts membrane-bound protgf-alpha to soluble tgf-alpha; mw 84 kD
Registry number: EC 3.4.21.-
Synonym: protgf-alpha converting enzyme, protgfalpha processing protease
(26 Jun 1999)
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  • Transforming Growth Factor alpha - 새창 Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to EPIDERMAL GROWTH FACTOR and binds to the EGF receptor. TGF-alpha acts synergistically with TGF-beta in inducing phenotypic transformation, but its physiological role is unknown.
    Synonyms : TGFalpha, Epidermal Growth Factor Related Transforming Growth Factor
  • Transforming Growth Factor beta - 새창 A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
    Synonyms : Milk Growth Factor, TGFbeta, Bone Derived Transforming Growth Factor, Factor, Milk Growth, Growth Factor, Milk
  • Transforming Growth Factor beta1 - 새창 A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
    Synonyms : TGF-beta-1, TGF-beta1 Latency-Associated Protein, TGF-beta1LAP, Transforming Growth Factor beta 1 Latency Associated Peptide, Transforming Growth Factor beta I, Latency-Associated Protein, TGF-beta1, TGF beta 1, TGF beta1 Latency Associated Protein
  • Transforming Growth Factor beta2 - 새창 A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
    Synonyms : BSC-1 Cell Growth Inhibitor, Cartilage-Inducing Factor-B, Glioblastoma-Derived T-Cell Suppressor Factor, Polyergin, Suppressor Factor, T-Cell, Glioblastoma-Derived, TGF-beta-2, TGF-beta2 Latency-Associated Protein, TGF-beta2LAP, BSC 1 Cell Growth Inhibitor
  • Transforming Growth Factor beta3 - 새창 A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
    Synonyms : TGF-beta-3, TGF-beta3 Latency-Associated Protein, TGF-beta3LAP, TGFB3, Transforming Growth Factor beta 3 Latency Associated Peptide, Latency-Associated Protein, TGF-beta3, TGF beta 3, TGF beta3, TGF beta3 Latency Associated Protein
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  • transforming - 새창
  • transforming growth factor - 새창
  • transforming principle - 새창
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transforming a. a substance that produces transformation in a cell, e.g., a DNA fragment from a bacterial (donor) cell that, when introduced into another bacterial (recipient) cell, is incorporated into the chromosome and produces a permanent, inherited change.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
transforming growth f. any of several proteins secreted by transformed cells and stimulating growth of normal cells, although not causing transformation. TGF-α binds the epidermal growth factor receptor and also stimulates growth of microvascular endothelial cells. TGF-β exists as several subtypes, all of which are found in hematopoietic tissue, stimulate wound healing, and in vitro are antagonists of lymphopoiesis and myelopoiesis.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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transforming a gene that causes normal cells to change into cancerous tumor cells
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