| ASD | aldosterone secretion defect; Alzheimer senile dementia; antisiphon device; arthritis syphilitica de... |
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| DMD | disease-modifying drug; Doctor of Dental Medicine; Duchenne muscular dystrophy; dystonia musculorum ... |
| PLT | pancreatic lymphocytic infiltration; platelet; primed lymphocyte test; primed lymphocyte typing; psi... |
| TRIC | trachoma inclusion conjunctivitis [organism] |
| granular trachoma | <ophthalmology> The ordinary form of trachoma marked by the presence of granulations on the conjunctiva. Synonym: granular trachoma. (05 Mar 2000) |
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| trachoma | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| trachoma bodies | Distinctive, complex, intracytoplasmic forms found in the conjunctival epithelial cells of persons in the acute phase of trachoma, less frequently in later stages, varying from 1) discrete acidophilic granules (approximately 250 nm in diameter), to 2) irregular clumps of such material embedded in a basophilic matrix, to 3) relatively large basophilic body's (approximately 700 to 1000 nm in diameter), to 4) large basophilic body's that include discrete, tiny, acidophilic granules. Synonym: Halberstaedter-Prowazek bodies, Prowazek-Greeff bodies. (05 Mar 2000) |
| trachoma glands | Lymph nodes in the palpebral conjunctiva. Synonym: trachoma glands. (05 Mar 2000) |
| trachoma virus | Former name for Chlamydia trachomatis. (05 Mar 2000) |
| follicular trachoma | <ophthalmology> The ordinary form of trachoma marked by the presence of granulations on the conjunctiva. Synonym: granular trachoma. (05 Mar 2000) |
| arthritis deformans | A systemic disease, seen more commonly in women which affects connective tissue, particularly the synovial tissue within joints. Arthritis is the main clinical feature and involves many joints in the body, especially those of the hand and feet. In this disease, there is thickening of the soft tissues around the joints and extension of the synovial tissue over articular cartilage (which becomes eroded). A chronic and progressive course is common with joint deformities and disability. Juvenile rheumatoid arthritis is a variant which affects children. (27 Sep 1997) |
| peritonitis deformans | A chronic peritonitis in which thickening of the membrane and contracting adhesions cause shortening of the mesentery and kinking and retraction of the intestines. (05 Mar 2000) |
| hyperostosis corticalis deformans | Marked irregular thickening of the skull and bone cortex, with thickening and widening of the shafts of long bones and high serum alkaline phosphatase; autosomal recessive inheritance. (05 Mar 2000) |
| spondylitis deformans | Arthritis and osteitis deformans involving the spinal column; marked by nodular deposits at the edges of the intervertebral disks with ossification of the ligaments and bony ankylosis of the intervertebral articulations, it results in a rounded kyphosis with rigidity. Synonym: Bechterew's disease, poker back, Strumpell's disease. (05 Mar 2000) |
| dystonia musculorum deformans | A genetic, environmental, or idiopathic disorder, usually beginning in childhood or adolescence, marked by muscular contractions that distort the spine, limbs, hips, and sometimes the cranial-innervated muscles. The abnormal movements are increased by excitement and, at least initially, abolished by sleep. The musculature is hypertonic when in action, hypotonic when at rest. Hereditary forms usually begin with involuntary posturing of the foot or hand (autosomal recessive form ) or of the neck or trunk (autosomal dominant form ); both forms may progress to produce contortions of the entire body. Synonym: progressive torsion spasm, torsion disease of childhood, torsion dystonia, Ziehen-Oppenheim disease. (05 Mar 2000) |
| osteitis deformans | This is a disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. Many patients are asymptomatic and diagnosed by routine X-rays. (27 Sep 1997) |
| osteochondritis deformans juvenilis | perthes disease |
| osteochondritis deformans juvenilis dorsi | Osteochondrosis of the vertebral epiphyses in children. (12 Dec 1998) |
| osteochondrodystrophia deformans | Term used for a group of disorders of bone and cartilage which includes Morquio syndrome and similar conditions. Synonym: osteochondrodystrophia deformans, osteochondrodystrophy. (05 Mar 2000) |
| trachoma deformans |
Trachoma with scarring.
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