| 영문 | thymus(gland) | 한글 | 가슴샘 |
|---|---|---|---|
| 설명 | 가슴의 앞 위쪽에 위치한 림프성 장기로서, 사춘기에 최고의 무게에 달했다가 이후에 퇴축한다. 이것은 세포매개 면역(cell-mediated immunity: 주로 T-림프구에 의해 일어나며, 자기와 다른 세포에 대한 인식과 이식거부반응에 관여함)기능의 발달과 성숙에 필요한 장기이며, 회백적색으로 보통 정중면에서 결합조직에 의해 결합된 두 개의 엽으로 되어 있다. 가슴샘은 상피세포, 림프구, 가슴샘세포로 구성되어 있으며 전구세포가 가슴샘에 이행하여 림프구로 분화되고, 그 대부분은 파괴되나 나머지는 T림프구를 형성한다. 가슴샘은 또한 호르몬 유사물질인 thymine, thymopoietin, thymosin 등을 분비한다. |
||
| 영문 | lymphocyte | 한글 | 림프구 |
|---|---|---|---|
| 설명 | 면역기능을 담당하는 세포. 골수에서 만들어지며, 림프구는 크게 2가지로 대분된다. 이른바 T림프세포, B림프세포로 나뉘어지게 된다. T림프세포는 세포성면역에 관여하며, 주로 바이러스병에 대한 면역기능이나, 알레르기(면역반응 4번형 등) 등에 관여한다. 이에 비해 B림프세포는 체액성면역에 관여하여, 항원 항체 반응을 일으키는 항체를 생산하고 주로 세균감염에 대한 면역기능을 담당한다. |
||
| 영문 | T-lymphocyte | 한글 | 티 림프구 |
|---|---|---|---|
| 설명 | 림프계세포(림프구)는 크게 2가지로 대분된다. 이른바 T림프세포(T-cell), B림프세포(B-cell)로 나뉘어진다. T림프세포는 세포성 면역에 관여하며, 주로 바이러스병에 대한 면역기능이나, 알레르기 등에 관여한다. 이에 비해 B림프세포는 체액성 면역에 관여하여, 항원 항체 반응을 일으키는 항체를 생산하고 주로 세균성 질환에 대한 면역 기능을 담당한다. T-림프구는 면역기능에 가장 중요한 역할을 하는 세포로서 세포면역을 담당하며 B-cell의 작용을 조절하는 기능도 있다. 골수에서 생성되어 가슴샘에서 성숙된다. 크게 보조T세포(helper T-cell: 면역작용의 발생을 보조한다)와 T세포(suppressor T-cell: 면역작용의 발생을 억제한다)로 구분되며 이들은 세포 표면에 분포하는 항원에 의해서 식별될 수 있다. |
||
| TL | temporal lobe; terminal limen; thermolabile; thermoluminescence; threat to life; thymus-leukemia [an... |
|---|---|
| TP | temperature and pressure; temperature probe; temporal peak; temporoparietal; tension pneumothorax; t... |
| TPF | thymus permeability factor; thymus to peak flow; true positive fraction |
| TCE | T-cell enriched; tetrachlorodiphenyl ethane; trichloroethylene T-cell thymus-derived cell |
| TDL | thoracic duct lymph; thymus-dependent lymphocyte; toxic dose level |
| CTL | Cytotoxic thymus-derived lymphocytes |
|---|---|
| LDCF | Lymphocyte-Derived Chemotactic Factor |
| CT | Calf thymus |
| FTOC | Fetal Thymus Organ Culture |
| FT | fetal thymus |
| thymus derived lymphocyte | <haematology, immunology> A class of lymphocytes, so called because they are derived from the thymus and have been through thymic processing. Involved primarily in controlling cell-mediated immune reactions and in the control of B-cell development. The T-cells coordinate the immune system by secreting lymphokine hormones. There are 3 fundamentally different types of t cells : helper, killer, and suppressor. Each has many subdivisions. T-cells are also called t lymphocytes. They bear T-cell antigen receptors (CD3) and lack Fc or C3b receptors. Major T-cell subsets are CD4 (mainly helper cells) and CD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to T-cell leukaemia/lymphoma. (21 Jun 1999) |
|---|
| lymphocyte lymphocyte | A type of non-granular antibodies. (09 Oct 1997) |
|---|---|
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| mammary derived growth inhibitor | Fatty acid binding protein that inhibits proliferation of mammary carcinoma cells. (18 Nov 1997) |
| receptors, platelet-derived growth factor | Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain. (12 Dec 1998) |
| refuse-derived fuel | (RDF) Fuel prepared from municipal solid waste. Noncombustible materials such as rocks, glass, and metals are removed, and the remaining combustible portion of the solid waste is choped or shreaded. RDF facilities process between 100 and 3000 tons of MSW per day. (05 Dec 1998) |
| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| platelet-derived growth factor | <growth factor> The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. Believed to play a role in wound healing. It is carried in the alpha-granules of platelets and is released when platelets adhere to traumatised tissues. Connective tissue cells near the traumatised region respond by initiating the process of replication. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus, that can transform only those cells that express receptors for platelet derived growth factor, suggesting that transformation is caused by autocrine stimulation. The receptor is a tyrosine kinase. Acronym: PDGF (12 Dec 1998) |
| schwannoma derived growth factor | <growth factor> A growth factor containing an EGF like domain, mitogenic for astrocytes, Schwann cells and fibroblasts. (18 Nov 1997) |
| derived protein | A derivative of protein effected by chemical change, e.g., hydrolysis. (05 Mar 2000) |
| oxygen derived free radicals | An atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, one-electron reduction of O2 produces the superoxide radical, O2-; other examples include the hydroperoxyl radical (HOO-), the hydroxyl radical (HO-), and nitric oxide (NO-). (05 Mar 2000) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| endothelium derived relaxation factor | <biochemistry> This compound is produced from L arginine by the enzyme nitric oxide synthase. Acts as a potent vasorelaxant via elevation of intracellular cGMP in vascular smooth muscle. Synthesis of nitric oxide is not confined to endothelium, isoforms of nitric oxide synthase are also found in brain, neutrophils and platelets. Synonym: endothelium derived relaxation factor. Acronym: NO (29 Dec 1997) |
| endothelium-derived relaxing factor | A labile humoral agent released by the vascular endothelium that mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin. Edrf also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. These actions are believed to be mediated through stimulation of guanylate cyclase and the consequent elevation of cyclic guanosine 3',5'-monophosphate. Edrf is thought to be nitric oxide or a ready source of it. The factor is believed to be unstable and acts only locally in vivo. (12 Dec 1998) |
| ribonuclease h, calf thymus | <enzyme> A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms (particularly calf thymus) as well as retroviruses. Registry number: EC 3.1.26.4 (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|