| 영문 | thymus(gland) | 한글 | 가슴샘 |
|---|---|---|---|
| 설명 | 가슴의 앞 위쪽에 위치한 림프성 장기로서, 사춘기에 최고의 무게에 달했다가 이후에 퇴축한다. 이것은 세포매개 면역(cell-mediated immunity: 주로 T-림프구에 의해 일어나며, 자기와 다른 세포에 대한 인식과 이식거부반응에 관여함)기능의 발달과 성숙에 필요한 장기이며, 회백적색으로 보통 정중면에서 결합조직에 의해 결합된 두 개의 엽으로 되어 있다. 가슴샘은 상피세포, 림프구, 가슴샘세포로 구성되어 있으며 전구세포가 가슴샘에 이행하여 림프구로 분화되고, 그 대부분은 파괴되나 나머지는 T림프구를 형성한다. 가슴샘은 또한 호르몬 유사물질인 thymine, thymopoietin, thymosin 등을 분비한다. |
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| 영문 | IDDM(Insulin-Dependent Diabetes Mellitus) | 한글 | 인슐린의존당뇨병 |
|---|---|---|---|
| 설명 | IDDM은 당뇨병의 치료에 반드시 인슐린이 필요한 경우를 말한다. 주로 원인이 이자에 있는 인슐린을 분비하는 세포의 파괴이며 이로 인해서 당뇨병의 치료제로 쓰이는 인슐린의 분비를 촉진하는 약물이 이 IDDM에서는 쓰일 수가 없고 오직 인슐린만이 치료제로 쓸 수가 있다. 전형적인 인슐린 의존형 당뇨병은 소아에서 흔히 발생하고 인슐린 분비세포의 파괴에 의해서 인슐린 분비능은 거의 없다. |
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| 영문 | carcinoembryonic antigen | 한글 | 암배아항원 |
|---|---|---|---|
| 설명 | 원래 태아의 장조직에서 정상적으로 존재하는 물질로 태아기 이후에는 존재하지 않는 물질이다. 그러나 위, 간, 허파 등의 암이 있는 경우에 성인에서도 존재한다. 이를 이용해서 암의 치료효과 판정이나 재발여부의 조사에 이용한다. |
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| 영문 | antigen | 한글 | 항원 |
|---|---|---|---|
| 설명 | 특이한 면역반응을 일으킬 수 있는 어떠한 물질. 여기에서 말하는 특이한 면역반응이란 비특이적인 면역반응과는 반대되는 의미로 그 물질에 대해서 특이하게 반응할 수 있는 항체나 그 물질에 대해서 특이하게 반응할 수 있는 세포를 만드는 것을 말한다. |
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| TL | temporal lobe; terminal limen; thermolabile; thermoluminescence; threat to life; thymus-leukemia [an... |
|---|---|
| TD | tabes dorsalis; tardive dyskinesia; T-cell dependent; temporary disability; terminal device; tetanus... |
| TP | temperature and pressure; temperature probe; temporal peak; temporoparietal; tension pneumothorax; t... |
| TPF | thymus permeability factor; thymus to peak flow; true positive fraction |
| HLA | histocompatibility leukocyte antigen; histocompatibility locus antigen; homologous leukocyte antibod... |
| TD | Thymus-dependent |
|---|---|
| CT | Calf thymus |
| CTL | Cytotoxic thymus-derived lymphocytes |
| FTOC | Fetal Thymus Organ Culture |
| FT | fetal thymus |
| thymus-dependent zone | <anatomy> Mid cortical region of lymph node, area that is particularly depleted of T lymphocytes in thymectomised animals and is referred to as the thymus dependent area. (18 Nov 1997) |
|---|---|
| thymus-independent antigen | An antigen that does not require T helper cell activation in order for the host's B-cells to be stimulated. Repeating polymers such as polysaccharides are examples of T-independent antigens. (05 Mar 2000) |
| T-dependent antigen | An antigen that requires T helper cells in addition to appropriate B-cells. Most antigens are T-dependent. (05 Mar 2000) |
| ribonuclease h, calf thymus | <enzyme> A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms (particularly calf thymus) as well as retroviruses. Registry number: EC 3.1.26.4 (12 Dec 1998) |
| congenital aplasia of thymus | diGeorge syndrome |
| cortex of thymus | The outer part of a lobule of the thymus; it surrounds the medulla and is composed of masses of closely packed lymphocytes. (05 Mar 2000) |
| hypoplasia of the thymus and parathyroids | Also known as the digeorge syndrome (dgs), this disorder is characterised by (1) low blood calcium levels (hypocalcaemia) due to underdevelopment (hypoplasia) of the parathyroid glands needed to control calcium; (2) underdevelopment (hypoplasia) of the thymus, an organ behind the breastbone in which lymphocytes mature and multiply; and (3) defects of the outflow tracts from the heart. most cases of dgs are due to a microdeletion in chromosome band 22q11.2. A small number of cases have defects in other chromosomes, notably 10p13. Named after the american paediatric endocrinologist angelo digeorge. Another name for dgs is the third and fourth pharyngeal pouch syndrome (since the faulty structures in dgs are embryologically derived from the third and fourth pharyngeal pouches). (12 Dec 1998) |
| thymus | <anatomy> The lymphoid organ in which T lymphocytes are educated, mature and multiply. It is composed of stroma (thymic epithelium) and lymphocytes, almost entirely of the T-cell lineage. In mammals the thymus is just anterior to the heart within the rib cage, in other vertebrates in rather undefined regions of the neck or within the gill chamber in teleost fish. The thymus regresses as the animal matures. (18 Nov 1997) |
| thymus and parathyroids, hypoplasia of | See third and fourth pharyngeal pouch syndrome. (12 Dec 1998) |
| thymus derived lymphocyte | <haematology, immunology> A class of lymphocytes, so called because they are derived from the thymus and have been through thymic processing. Involved primarily in controlling cell-mediated immune reactions and in the control of B-cell development. The T-cells coordinate the immune system by secreting lymphokine hormones. There are 3 fundamentally different types of t cells : helper, killer, and suppressor. Each has many subdivisions. T-cells are also called t lymphocytes. They bear T-cell antigen receptors (CD3) and lack Fc or C3b receptors. Major T-cell subsets are CD4 (mainly helper cells) and CD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to T-cell leukaemia/lymphoma. (21 Jun 1999) |
| thymus extracts | Extracts of the thymus that contain specific, but uncharacterised factors or proteins with specific activities; three distinct substances are already known: thymotoxin, thymin and thymosin. (12 Dec 1998) |
| thymus gland | A bilaterally symmetric lymphoid organ situated in the anterior superior mediastinum. Each of its two lobes consists of an outer zone, the cortex, relatively rich in lymphocytes (thymocytes), and an inner zone, the medulla, relatively rich in epithelial cells. The thymus is the site of the production of T-lymphocytes. The thymus reaches its maximal development at about puberty and then undergoes a gradual process of involution resulting in a slow decline of immune function throughout adulthood. (12 Dec 1998) |
| thymus hormones | Humoral factors secreted by the thymus gland. They participate in the development of the lymphoid system and the maturation of the cellular immune response. (12 Dec 1998) |
| thymus hyperplasia | Enlargement of the thymus. A condition described in the late 1940's and 1950's as pathological thymic hypertrophy was status thymolymphaticus and was treated with radiotherapy. Unnecessary removal of the thymus was also practiced. It later became apparent that the thymus undergoes normal physiological hypertrophy, reaching a maximum at puberty and involuting thereafter. The concept of status thymolymphaticus has been abandoned. Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (12 Dec 1998) |
| thymus treatment | Treatment of disease by administration of extracts of thymus gland. (05 Mar 2000) |
| thymus dependent antigen |
One of the foreign antigens that require B lymphocyte stimulation by T cells before production of antibodies and memory cells can occur.
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보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
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보험코드 | 성분/함량 | 구분/보험급여 |
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