| TK | thymidine kinase; transketolase; triose-kinase; tyrosine kinase |
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| HAT | Halsted Aphasia Test; head, arm, trunk; heparin-associated thrombocytopenia; heterophil antibody tit... |
| TMP | thiamine monophosphate; thymidine monophosphate; thymidine-5'-monophosphate; thymolphthalein monopho... |
| AK | above knee; acetate kinase; adenosine kinase; adenylate kinase; artificial kidney |
| CK | calf kidney; casein kinase; chicken kidney; cholecystokinin; choline kinase; contralateral knee; cre... |
| TK | 2-thymidine kinase |
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| HSV1-TK | Herpes Simplex Virus Type 1-Thymidine Kinase |
| HSVtk | Herpes Simplex Virus thymidine kinase |
| HStk | Herpes Simplex thymidine kinase |
| HSV-tk | Herpes simplex thymidine kinase |
creatine kinase
| thymidine kinase | <enzyme> Of pyrimidine salvage, catalysing phosphorylation of thymine deoxyriboside to form its 5' phosphate, the nucleotide thymidylate. Animal cells lacking this enzyme can be selected by lethal synthesis, for example by resistance to bromodeoxyuridine and can be used as parentals in somatic hybridisation, since they are unable to grow in HAT medium. (18 Nov 1997) |
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| ADP - thymidine kinase | <enzyme> Induced by herpes simplex virus infection of mouse fibroblasts Registry number: EC 2.7.1.118 Synonym: ADP-thymidine 5'-phosphotransferase (26 Jun 1999) |
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| MAP kinase kinase kinase | <enzyme> From pc12 cells; reactivates map kinase kinase inactivated by protein phosphatase 2a by phosphorylation of serine residues; tak1 (tgf-beta-activated kinase 1) is a member of the mapkkk family; genbank ab006787 (mouse) Registry number: EC 2.7.10.- Synonym: mapkkk, tak1 mapkkk, ask1 (kinase), apoptosis signal-regulating kinase 1 (26 Jun 1999) |
| double thymidine block | <cell culture, procedure> A lab technique used to synchronise the cell cycles of all the cells in a culture. This is done by adding excessive amounts of thymidine (a deoxynucleoside) to the culture so that DNA replication is blocked. Eventually, all of the cells will reach the same point in the cell cycle and stop. (09 Oct 1997) |
| thymidine | <biochemistry> Term that is always used in practice for the nucleoside thymine deoxyriboside, not the riboside which naming of the other nucleosides might lead one to expect. (18 Nov 1997) |
| thymidine 5'-diphosphate | Thymidine esterified at its 5' position with diphosphoric acid. Acronym: dTDP (05 Mar 2000) |
| thymidine 5'-monophosphate | A major constituent of DNA. Synonym: thymidine 5'-monophosphate, thymine nucleotide. (05 Mar 2000) |
| thymidine 5'-triphosphate | Thymidine esterified at its 5' position with triphosphoric acid; the immediate precursor of thymidylic acid in DNA. Acronym: dTTP (05 Mar 2000) |
| thymidine-diphospho-4-keto-6-deoxyglucose epimerase | <enzyme> Isolated from saccharopolyspora erythraea; catalyses the formation of tdp-4-keto-l-rhamnose from thymidine-diphospho-4-keto-6-deoxy-d-glucose Registry number: EC 5.1.3.- Synonym: tdkd-glucose epimerase, tdp-4-keto-6-deoxyglucose 3,5-epimerase, kde gene product (26 Jun 1999) |
| thymidine monophosphate | <chemical> 5-thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. Chemical name: 5'-Thymidylic acid (12 Dec 1998) |
| thymidine permease | <chemical> (26 Jun 1999) |
| thymidine phosphorylase | <enzyme> The enzyme catalyzing the transfer of 2-deoxy-d-ribose from thymidine to orthophosphate, thereby liberating thymidine. Chemical name: Thymidine:orthophosphate deoxy-D-ribosyltransferase Registry number: EC 2.4.2.4 (12 Dec 1998) |
| thymidine triphosphate | A molecule which consists of the nitrogenous base thymine linked to the sugar ribose and which has a chain of three phosphate groups attached to the ribose in a linear fashion. TTP is required for DNA and RNA synthesis since it is a direct precursor molecule. (09 Oct 1997) |
| tritiated thymidine | Thymidine containing the hydrogen radionuclide, tritium (H); used as a marker to measure and localise by radioautography the synthesis of DNA, into which it is incorporated. (05 Mar 2000) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| calmodulin-dependent protein kinase IV kinase | <enzyme> Phosphorylates and activates cam-kinase iv; from brain Registry number: EC 2.7.10.- Synonym: cam-kinase iv kinase (26 Jun 1999) |
Synonyms : Deoxypyrimidine Kinase, Kinase, Deoxypyrimidine, Kinase, Deoxythymidine, Kinase, Thymidine
| thymidine kinase |
[EC 2.7.1.21] an enzyme of the transferase class that catalyzes the ATP-dependent phosphorylation of thymine deoxyribonucleoside, a reaction of pyrimidine salvage. Because the reaction produces an easily selectable phenotype, the gene and promoter are used extensively in genetic research.
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