| APP | acute phase protein; alum-precipitated pyridine; aminopyrazolopyrimidine; amyloid peptide precursor;... |
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| ECP | ectrodactyly-cleft palate [syndrome]; effector cell precursor; endocardial potential; eosinophil cat... |
| CTD | carpal tunnel decompression; chest tube drainage; congenital thymic dysplasia; connective tissue dis... |
| CTE | calf thymus extract; cultured thymic epithelium |
| HTL | hamster tumor line; hearing threshold level; high-L-leucine transport; histotechnologist; human T-ce... |
| TNC | Thymic nurse cells |
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| TSC | Thymic stromal cells |
| FTOC | Fetal thymic organ cultures |
| RTE | Recent thymic emigrants |
| T | Thymic |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
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| amyloid beta-protein precursor | A precursor to the amyloid-beta protein (beta/a4). Alterations in the expression of the amyloid beta-protein precursor (abpp) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both alzheimer disease and down syndrome. Abpp is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/a4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in alzheimer disease, down syndrome and, to a limited extent, in normal aging. (12 Dec 1998) |
| amyloid precursor protein | <protein> Individuals with Alzheimer's disease are characterised by extensive accumulation of amyloid in the brain, referred to as senile plaques. These consist of a core of amyloid fibrils surrounded by dystrophic neurites. The principal component of the amyloid fibrils is B/A4, a peptide derived from the larger APP. The specific role of amyloid protein is unclear but it is thought that amyloid deposits may cause neurons to degenerate. Amyloid deposits also occur in brains of older Down's Syndrome patients. (04 May 1997) |
| angiotensin precursor | angiotensin |
| precursor | Something that precedes. 1. <biochemistry> In biological processes, a substance from which another, usually more active or mature substance is formed. 2. In clinical medicine, a sign or symptom that heralds another. Origin: L. Praecursor = a forerunner (18 Nov 1997) |
| enzyme precursor | <biochemistry> Inactive precursors that can be converted to active enzymes. Enzyme precursors containing extra-long polypeptide chains that block activity are activated by acid or enzymatic hydrolysis to remove the inhibiting portion. (12 Dec 1998) |
| mouse thymic virus | An unclassified ether-sensitive virus, 75 to 100 nm in diameter, that causes necrosis of the thymus in young mice. (05 Mar 2000) |
| Nezelof type of thymic alymphoplasia | Synonym: cellular immunodeficiency with abnormal immunoglobulin synthesis. (05 Mar 2000) |
| thymic | <anatomy> Of or pertaining to the thymus gland. <medicine> Pertaining to, or derived from, thyme; as, thymic acid. Source: Websters Dictionary (01 Mar 1998) |
| thymic abscesses | Small cysts of the thymus containing polymorphonuclear leukocytes but lined by squamous epithelium; reported in congenital syphilis but also found in the absence of syphilis. Synonym: Dubois' disease, thymic abscesses. (05 Mar 2000) |
| thymic acid | Synonym: thymol. Origin: see thyme (05 Mar 2000) |
| thymic agenesis | The absence of the thymus, which may be associated with parathyroid agenesis in DiGeorge syndrome. (05 Mar 2000) |
| thymic alymphoplasia | Hypoplasia with absence of Hassall's corpuscles and deficiency of lymphocytes in the thymus and usually in lymph nodes, spleen, and gastrointestinal tract; there is peripheral lymphopenia and often hypogammaglobulinaemia and absence of plasma cells; presents in early infancy with respiratory infections and leads to death within a few months. See: immunodeficiency with hypoparathyroidism. (05 Mar 2000) |
| thymic aplasia | <disease, immunology> A lack of T lymphocytes, due to failure of the thymus to develop, resulting in very reduced cell-mediated immunity though serum immunoglobulin levels may be normal. See: DiGeorge syndrome. Origin: Gr. Plassein = to form (18 Nov 1997) |
| thymic arteries | <anatomy, artery> Small twigs supplying anterior mediastinal structures: mainly thymus and lymph nodes. Synonym: rami mediastinales arteriae thoracicae internae, rami thymici, anterior mediastinal arteries, arteriae thymicae, thymic arteries. (05 Mar 2000) |
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