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  • thromboxane synthetase
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TB Taussig-Bind [syndrome]; terabyte; term birth; terminal bronchiole; terminal bronchus; thromboxane B...
TBX thromboxane; total body irradiation
TBXA2 thromboxane A2
TBXAS thromboxane A synthase
Thx thromboxane
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11-dehydro-TXB2 11 dehydro-thromboxane B2
11-dTXB2 11-dehydro-thromboxane B(2
CTA2 Carbocyclic thromboxane A2
i-TXB2 Immunoreactive thromboxane B2
TXA2 PGE2)/thromboxane A2
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  • thrombotonin µ¿ÀǾî=serotonin.

    thromboxane

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thromboxane <biochemistry> Arachidonic acid metabolites produced by the action of thromboxane synthetase on prostaglandin cyclic endoperoxides. Thromboxane A2 (TxA2) is a potent inducer of platelet aggregation and release and although unstable, the activation of platelets leads to the further production of TxA2. Also causes arteriolar constriction. Another endoperoxide product, prostacyclin, has the opposite effects.
(18 Nov 1997)
thromboxane a2 <chemical> An unstable intermediate between the prostaglandin endoperoxides and thromboxane b2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (rcs).
Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-
(12 Dec 1998)
thromboxane b2 <chemical> A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).
Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-
(12 Dec 1998)
thromboxane dehydrogenase <enzyme> Converts thromboxane b2 to 11-dehydro-thromboxane b2, but not the reverse reaction; uses nad but not nadp as cofactor; only attacks the 11-hydroxy group of txb2
Registry number: EC 1.1.1.-
Synonym: thromboxane b2 dehydrogenase, 11-hydroxythromboxane b2 dehydrogenase, 11-hydroxy-txb2 dehydrogenase
(26 Jun 1999)
thromboxane-a synthase <enzyme> An enzyme found predominantly in platelet microsomes. It catalyses the conversion of pgg(2) and pgh(2) (prostaglandin endoperoxides) to thromboxane a2.
Chemical name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase
Registry number: EC 5.3.99.5
(12 Dec 1998)
thromboxanes Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
(12 Dec 1998)
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receptors, thromboxane Cell surface proteins that bind thromboxanes with high affinity and trigger intracellular changes influencing the behaviour of cells. at least a subset of thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.
(12 Dec 1998)
prostaglandin endoperoxide thromboxane isomerase <enzyme> Converts prostaglandin h2 to thromboxane b2 and 12l-hydroxy-5,8,10-heptadecatrienoic acid
Registry number: EC 5.3.99.-
Synonym: endoperoxide-tx isomerase, pg endoperoxide thromboxane isomerase
(26 Jun 1999)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 4 ÆäÀÌÁö: 1
  • Thromboxane A2 - »õâ An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
    Synonyms : A2, Thromboxane
  • Thromboxane B2 - »õâ A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).
    Synonyms : B2, Thromboxane
  • Thromboxane-A Synthase - »õâ An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
    Synonyms : Thromboxane A Synthase, Thromboxane A2 Synthetase, A2 Synthetase, Thromboxane, Synthase, Thromboxane A, Synthase, Thromboxane-A, Synthetase, Thromboxane, Synthetase, Thromboxane A2
  • Thromboxanes - »õâ Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase.
    Synonyms :
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thromboxane A type of eicosanoid which causes clotting of blood and increases stickiness of platelets. The thromboxane produced from omega-3 fatty acids is devoid of any activity.
Ãâó: niazi.com/Omega/glossary.htm
thromboxane-A synthase [EC 5.3.99.5] an enzyme of the isomerase class that catalyzes the conversion in platelets of prostaglandin G2 to thromboxane A2, a potent vasoconstrictor and platelet agonist. Deficient enzyme activity, an autosomal dominant trait, causes defects in the release of platelets. See also illustration at prostaglandin.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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