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  • thrombospondin
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THBS thrombospondin
TSP testis-specific protein; thrombin-sensitive protein; thrombospondin; total serum protein; total susp...
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TS Thrombospondin
TSP Thrombospondin
TSP-1 Thrombospondin 1
TSP2 Thrombospondin 2
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thrombospondin <cell biology> Homotrimeric glycoprotein (450 kD) from _ granules of platelets and synthesised by various cell types in culture. Also found in extracellular matrix of cultured endothelial, smooth muscle and fibroblastic cells. May have autocrine growth regulatory properties: involved in platelet aggregation.
(18 Nov 1997)
thrombospondin 1 An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumour growth and metastasis.
(12 Dec 1998)
thrombospondins A family of related, adhesive glycoproteins which are synthesised, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of blood coagulation factors and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (comp). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumour metastasis, vascular smooth muscle growth, and tissue repair.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 2 ÆäÀÌÁö: 1
  • Thrombospondin 1 - »õâ An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
    Synonyms : 1, Thrombospondin
  • Thrombospondins - »õâ A family of related, adhesive glycoproteins which are synthesized, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of BLOOD COAGULATION FACTORS and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (COMP). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumor metastasis, vascular smooth muscle growth, and tissue repair.
    Synonyms : Thrombospondin
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thrombospondin Family of extracellular adhesive proteins with five members (THBS-1 through THBS-4, and cartilage oligomeric matrix protein [COMP]), THBSs play a role in several cellular processes, including platelet aggregation and angiogenesis.
Ãâó: www.jco.org/cgi/glossarylookup
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