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| HIT | hemagglutination inhibition test; heparin-induced thrombocytopenia; histamine inhalation test; hyper... |
|---|---|
| HITT | heparin-induced thrombocytopenia and thrombosis |
| HITTS | heparin-induced thrombosis-thrombocytopenia syndrome |
| DIT | deferoxamine infusion test; diet-induced thermogenesis; diiodotyrosine; drug-induced thrombocytopeni... |
| HAT | Halsted Aphasia Test; head, arm, trunk; heparin-associated thrombocytopenia; heterophil antibody tit... |
| HIT | Heparin induced thrombocytopenia |
|---|---|
| HIT II | Heparin-induced thrombocytopenia type II |
| HAT | Heparin associated thrombocytopenia |
| LMW heparin | Low Molecular Weight heparin |
| HELP | Heparin-induced Extracorporeal LDL-Precipitation |
| heparin | <drug> Sulphated mucopolysaccharide, found in granules of mast cells, that inhibits the action of thrombin on fibrinogen by potentiating antithrombins, thereby interfering with the blood clotting cascade. Platelet factor IV will neutralise heparin. (18 Nov 1997) |
|---|---|
| heparin antagonists | Coagulant substances inhibiting the anticoagulant action of heparin. (12 Dec 1998) |
| heparin binding growth factor | <growth factor> Acidic fibroblast growth factor (alpha FGF, HBGF 1) and basic FGF (beta FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal or neuroectodermal cells. Synonym: heparin binding growth factor. Acronym: FGF (18 Nov 1997) |
| heparin cofactor II | <chemical> A sulfated plasma protein with the mw of approximately 66kda. The protein is an inhibitor of thrombin in plasma that is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily. Pharmacological action: serine proteinase inhibitors. Chemical name: Heparin cofactor II (12 Dec 1998) |
| heparin complement | The protein component of heparin in blood. (05 Mar 2000) |
| heparin eliminase | <enzyme> An enzyme of the isomerase class that catalyses the eliminative cleavage of polysaccharides containing 1,4-linked d-glucuronate or l-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-d-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-d-gluc-4-enuronosyl groups at their non-reducing ends. Chemical name: heparin lyase Registry number: EC 4.2.2.7 (12 Dec 1998) |
| heparin-glucosamine 3-O-sulfotransferase | <enzyme> Reaction: 3'-phosphoadenylylsulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin glucosamine 3-o-sulfate Registry number: EC 2.8.2.23 Synonym: glucosaminyl 3-o-sulfotransferase, d-glucosaminyl 3-o-sulfotransferase (26 Jun 1999) |
| heparin, low-molecular-weight | <chemical> Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of haemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism. Pharmacological action: anticoagulant, fibrinolytic agent. (12 Dec 1998) |
| heparin lyase | <enzyme> An enzyme of the isomerase class that catalyses the eliminative cleavage of polysaccharides containing 1,4-linked d-glucuronate or l-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-d-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-d-gluc-4-enuronosyl groups at their non-reducing ends. Chemical name: heparin lyase Registry number: EC 4.2.2.7 (12 Dec 1998) |
| heparin unit | The quantity of heparin required to keep 1 ml of cat's blood fluid for 24 hr at 0°C; it is equivalent approximately to 0.002 mg of pure heparin. Synonym: Howell unit. (05 Mar 2000) |
| autoimmune thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| canine infectious cyclic thrombocytopenia | An infection of dogs with the rickettsia Ehrlichia platys characterised by recurrent cyclic thrombocytopenia. (05 Mar 2000) |
| radial aplasia-thrombocytopenia syndrome | <syndrome> Aplasia (absence) of the radius (the long bone on the thumb-side of the forearm) and thrombocytopenia (low blood platelets) are key features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the child affected with the disease. Alternative names include thrombocytopenia-absent radius syndrome, tar syndrome, and tetraphocomelia-thrombocytopenia syndrome. (12 Dec 1998) |
| haemangioma-thrombocytopenia syndrome | <syndrome> Thrombocytopenia caused by sequestration and destruction of platelets in a large cavernous haemangioma, usually seen in infants, rare in adults (12 Dec 1998) |
| syndrome, radial aplasia-thrombocytopenia | See syndrome, tar. (12 Dec 1998) |
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