| thiaminase | 1. An enzyme present in raw fish that destroys thiamin and may produce thiamin deficiency in animals on a diet largely composed of raw fish. 2. A hydrolase cleaving thiamin into a pyrimidine moiety (i.e., 2-methyl-4-amino-5-hydroxymethylpyrimidine) and a thiazole moiety (i.e., 4-methyl-5-(2'-hydroxyethyl)-thiazole); the pyrimidine moiety may appear in the urine as pyramin. Synonym: thiaminase II. (05 Mar 2000) |
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| thiaminase I | <enzyme> An enzyme catalyzing transfer of a pyridine or other bases into the position of the pyrimidine in thiamin; e.g., thiamin reacting with pyridine produces heteropyrithiamin and 4-methyl-5-(2'-hydroxyethyl)-thiazole. Synonym: pyrimidine transferase, thiaminase I. (05 Mar 2000) |
| thiaminase II | 1. An enzyme present in raw fish that destroys thiamin and may produce thiamin deficiency in animals on a diet largely composed of raw fish. 2. A hydrolase cleaving thiamin into a pyrimidine moiety (i.e., 2-methyl-4-amino-5-hydroxymethylpyrimidine) and a thiazole moiety (i.e., 4-methyl-5-(2'-hydroxyethyl)-thiazole); the pyrimidine moiety may appear in the urine as pyramin. Synonym: thiaminase II. (05 Mar 2000) |
| thiaminase |
[EC 3.5.99.2] an enzyme of the hydrolase class that catalyzes the cleavage of thiamine into its component pyrimidine and thiazole moieties, inactivating it. The enzyme is present in intestinal microorganisms. Called also t. II.
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