| ¿µ¹® | toxin | ÇÑ±Û | µ¶¼Ò |
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| ¼³¸í | »ý¹°Ã¼°¡ ¸¸µé¾î³»´Â µ¶¼º°ú Ç׿ø¼ºÀ» °¡Áø ¹°Áú. µ¶¼Ò¸¦ Àû´çÇÑ µ¿¹°¿¡ ÁÖ»çÇϸé Ç×üÀÎ Ç×µ¶¼Ò°¡ »ý¼ºµÇ°í, ÀÌ Ç×µ¶¼Ò¿Í µ¶¼Ò´Â ƯÀÌÀûÀ¸·Î °áÇÕÇÑ´Ù. ¼¼±Õ¿¡ ÀÇÇÑ ´Ü¹éºÐÇØ»ê¹°·Î ¸Íµ¶¼ºÀ» ¹ßÈÖ³ª´Â °Í¿¡ ¾Æ¹ÎÀÌ ÀÖÀ¸³ª, À̰Ϳ¡´Â Ç׿ø¼ºÀÌ ¾øÀ¸¹Ç·Î µ¶¼Ò°¡ ¾Æ´Ï´Ù. ÀϹÝÀûÀ¸·Î Áßµ¶Áõ»óÀ» ¹ßÇöÇϴµ¥ ÀÏÁ¤ÇÑ ½Ã°£ÀÌ °É¸®¸ç, µ¿¹°¿¡ µû¶ó °¨¼ö¼ºÀÌ ´Ù¸¥ Á¡ÀÌ µ¶¹°°ú ´Ù¸£´Ù. µ¶¼Ò¿¡´Â »ý¹°Ã¼ ¾È¿¡ ¸¸µé¾îÁ® ³²¾Æ ÀÖ´Ù°¡ »ý¹°Ã¼°¡ ÆÄ±«µÇ¾úÀ» ¶§ µ¶¼ºÀ» °®´Â ³»µ¶¼Ò(endotoxins)¿Í »ý¹°Ã¼°¡ ÁÖº¯À¸·Î ¹°ÁúÀ» ºÐºñÇÏ´Â ¿Üµ¶¼Ò(exotoxins)°¡ ÀÖ´Ù. µ¶¼Ò¸¦ ³»´Â »ý¹°Ã¼¿¡ µû¶ó ¼¼±Õ¼º µ¶¼Ò ¿Ü¿¡ µ¿¹°¼º µ¶¼Ò ¹× ½Ä¹°¼º µ¶¼Ò°¡ ÀÖ´Ù. µ¿¹°¼º µ¶¼Ò´Â ´ëºÎºÐ µ¶¼±¿¡¼ ºÐºñµÇ¸ç, ¹ì-Àü°¥-°Å¹Ì-¹ú µîÀÌ ´ëÇ¥ÀûÀÎ °ÍÀÌ´Ù. ½Ä¹°¼º µ¶¼Ò·Î´Â ¸®½Å(ricin)-¾Æºê¸°(abrin)-·Îºñ´Ñ(robinin)-Å©·Îƾ(crotin) µîÀÌ ÀÖ´Ù. ¼¼±ÕÀº ÀÎü¿¡ ¿µÇâÀ» ¹ÌÃÄ µðÇÁÅ׸®¾Æ-ÆÄ»ódz-¼ºÈ«¿-°¡½º±«Àú µîÀ» ÀÏÀ¸Å°°í, ¶Ç ¾î¶² ¼¼±Õ°ú ¹ö¼¸·ù´Â »ýÀåÇÒ ¶§ µ¶¼Ò¸¦ ºÐºñ, À̰ÍÀ» ¸ÔÀ¸¸é º¸Åø¸®´©½º Áßµ¶-¸Æ°¢ Áßµ¶ µîÀ» ÀÏÀ¸Å²´Ù. ±× ¹Û¿¡ ¹°°í±â¿¡µµ µ¶¼ºÀ» °¡Áø °ÍÀÌ ÀÖ´Ù. ÀÎü¿¡´Â µ¶¼Ò°¡ µé¾î¿ÔÀ» ¶§ ±×¿Í °áÇÕÇÏ¿© µ¶¼ºÀ» ÇØµ¶½ÃŰ´Â Ç×µ¶¼Ò°¡ Ç÷û-¸²ÇÁ¾× µî¿¡ »ý±ä´Ù. |
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| ¿µ¹® | tetanus | ÇÑ±Û | Áö¼Ó±Ù°Á÷, °Ãà |
|---|---|---|---|
| ¼³¸í | ±ÙÀ°¿¡ µÎ °³ ÀÌ»óÀÇ ÀÚ±ØÀ» ªÀº °£°ÝÀ¸·Î ¹Ýº¹ÇÏ¿© °¡Çϸé ÇϳªÇϳªÀÇ ´Ü¼öÃàÀÌ À¶ÇÕÇÏ¿© º¸´Ù Å« ¼öÃàÀÌ ³ªÅ¸³´Ù. ÀÌ·¯ÇÑ ¼öÃàÀ» °ÃàÀ̶ó ÇÑ´Ù. °Ãà½Ã ÃÖ´ëÀå·ÂÀº ÇÑ °³ÀÇ ¼öÃà½ÃÀÇ ¸î ¹è¿¡ À̸¥´Ù. ¹Ýº¹ÀÚ±Ø °£°ÝÀÌ ÃæºÐÈ÷ ªÀ» ¶§¿¡´Â ¿ÏÀüÈ÷ À¶ÇÕÇÏ°í ±× ¼öÃà°î¼±Àº ¿øÈ°ÇØÁö´Âµ¥ À̰ÍÀ» ¿ÏÀü°Ãà(complete tetanus)À̶ó ÇÑ´Ù. ¹Ýº¹ÀÚ±ØÀÇ °£°ÝÀÌ Áß°£Á¤µµÀÎ ¶§´Â ¿ÏÀüÈ÷ À¶ÇÕµÇÁö ¾Ê°í ¼öÃà°î¼±ÀÌ µ¿¿äÇϴµ¥, À̰ÍÀ» ºÒ¿ÏÀü°Ãà(incomplete tetanus)À̶ó°í ÇÑ´Ù. °ÃàÀ» ÀÏÀ¸Å³ ¼ö ÀÖ´Â ÀÚ±ØÀÇ ºóµµ´Â ±ÙÀ°ÀÇ Á¾·ù³ª µ¿¹°ÀÇ Á¾·ù¿¡ µû¶ó ´Ù¸£´Ù. |
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| ¿µ¹® | tetanus | ÇÑ±Û | ÆÄ»ódz |
|---|---|---|---|
| ¼³¸í | ÆÄ»ódz±ÕÀÌ ÀÏÀ¸Å°´Â ±Þ¼ºÀü¿°º´. »óó¸¦ ÅëÇÏ¿© °¨¿°Çϸç, ¸ö¼Ò¿¡¼ Áõ½ÄÇÑ ÆÄ»ódz±ÕÀÇ µ¶¼Ò°¡ ÁßÃ߽Űæ, ƯÈ÷ ô¼ö¸¦ ħ¹üÇÔÀ¸·Î½á ÀϾÙ. ÀÔÀÌ ±»¾îÁ®¼ ¹ú¸®±â ¾î·Æ°Ô µÇ°í, ÀÌ¾î¼ ¿Â ¸ö¿¡ °æÁ÷¼º °æ·ÃÀ» ÀÏÀ¸Å²´Ù. »ç¸Á·üÀÌ ³ôÀ¸¸ç, ¿¹¹æÁ¢Á¾ÀÌ À¯È¿ÇÏ´Ù. À̰ÍÀº ÆÄ»ódz±Õ(Clostridium tetani)¿¡¼ »ý»êµÇ´Â ¿Üµ¶¼Ò°¡ ¿øÀÎÀÌ´Ù. |
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| TAT | 1) Thematic Apperception Test; ÁÖÁ¦ Åë°¢ °Ë»ç 2) (Equine) Tetanus Anti-Toxin; Ç×... |
|---|---|
| TT | tablet triturate; tactile tension; tendon transfer; test tube; testicular torsion; tetanus toxin; te... |
| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
| ET | educational therapy; effective temperature; ejection time; embryo transfer; endothelin; endotoxin; e... |
| CDT | carbohydrate-deficient transferrin; carbon dioxide therapy; Certified Dental Technician; children's ... |
| TT | Tetanus toxin |
|---|---|
| TeTX | Tetanus toxin |
| TT | Anti-tetanus toxoid |
| DPT | Diphtheria Pertussis Tetanus |
| DTP | Diphtheria Tetanus and Pertussis |
| tetanus toxin | <protein> Neurotoxin released by Clostridium tetani, becomes active when peptide cleaved proteolytically to heavy (100 kD) and light (50 kD) chains held together by disulphide bond. Heavy chain binds to disialogangliosides (GD2 and GD1b) and part of the peptide (the amino terminal B fragment) forms a pore: light chain is a zinc endopeptidase that specifically attacks synaptobrevin, to block neurotransmitters. See: botulinum toxin (18 Nov 1997) |
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| animal toxin | <pharmacology> Any poisonous substance (including but not limited to venom) produced by an animal. (11 May 1997) |
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| anthrax toxin | A culture filtrate of Bacillus anthracis containing an exotoxin with at least three different antigenically distinct components: oedema factor, lethal factor, and protective antigen. Synonym: Bacillus anthracis toxin. (05 Mar 2000) |
| Bacillus anthracis toxin | A culture filtrate of Bacillus anthracis containing an exotoxin with at least three different antigenically distinct components: oedema factor, lethal factor, and protective antigen. Synonym: Bacillus anthracis toxin. (05 Mar 2000) |
| bacterial toxin | Any intracellular or extracellular toxin formed in or elaborated by bacterial cells. (05 Mar 2000) |
| bee toxin | The toxin delivered by a bee sting; contains three active principles: biogenic amines, active peptides, and certain hydrolytic enzymes. (05 Mar 2000) |
| botulinum toxin | <protein> Neurotoxin (50 kD, 7 distinct serotypes) produced by certain strains of Clostridium botulinum. The bacterium produces the toxin as a complex with a haemagglutinin that prevents toxin inactivation in the gut. Proteolysis in the body results in cleavage into two fragments A and B. B binds to gangliosides and may stimulate the endocytosis of fragment A. See: synaptobrevin, tetanus toxin. (18 Nov 1997) |
| botulinum toxin type a | <chemical> A neurotoxin produced by clostridium botulinum. When consumed in contaminated food it can cause paralysis and death. In its purified form, it has been used in the treatment of blepharospasm and strabismus. Pharmacological action: neuromuscular agents. (12 Dec 1998) |
| botulinus toxin | A potent neurotoxin from Clostridium botulinum. Synonym: botulin, botulismotoxin. (05 Mar 2000) |
| botulism toxin | <protein> A toxic byproduct of Clostridium Botulinum that is responsible for the food-borne illness known as botulism. (27 Sep 1997) |
| gamma toxin | <microbiology> Complex toxin (33.4 kD) produced by Staphylococcus aureus. Rabbit erythrocytes are particularly sensitive to lysis by the toxin, but the mechanism is unknown. (18 Nov 1997) |
| paralytic shellfish poisoning toxin carbamoylase | <enzyme> Hydrolytic enzyme from shellfish converts saxitoxin, neosaxitoxin, gonyautoxins 1 - 4 to the corresponding decarbamoyl toxins Registry number: EC 3.1.1.- Synonym: pcp toxin carbamoylase, saxitoxin carbamoylase (26 Jun 1999) |
| pertussis toxin | <protein> Protein complex (ca 117 kD). An A B toxin, the active subunit is a single polypeptide 28 kD), the binding subunit a pentamer (two heterodimers, 23 + 11.7 kD, 11.7 + 22 kD and a monomer (9.3 kD) that binds the heterodimers). The active subunit ADP ribosylates the _ subunit of the inhibitory GTP-binding protein (Gi). Crucial to the pathogenicity of Bordetella pertussis, the causative agent of whooping cough. (18 Nov 1997) |
| cholera toxin | <protein> A multimeric protein toxin from Cholera vibrio. The toxic A subunit activates adenyl cyclase irreversibly by ADP ribosylation of a Gs protein. The B subunit facilitates passage of the A subunit across the cell membrane. (18 Nov 1997) |
| cholera toxin, B subunit-horseradish peroxidase | <chemical> Conjugate of horseradish peroxidase and cholera toxin Synonym: bhrp, horseradish peroxidase-cholera toxin b subunit, cholera toxin-horseradish peroxidase, horseradish peroxidase-cholera toxin, ib4-hrp (26 Jun 1999) |
| cobra toxin | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
Synonyms : Tetanus Toxins, Neurotoxin, Clostridial, Toxin, Clostridium tetani, Toxin, Tetanus, Toxins, Tetanus
| tetanus toxin |
Protein derived from Clostridium tetani that can block transmitter release owing to its ability to degrade synaptobrevin. Tetanus toxin is the causative agent of tetanus.
Ãâó: www.nature.com/nrn/journal/v2/n3/glossary/nrn0301_...
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