| ¿µ¹® | signal transduction | ÇÑ±Û | ½ÅÈ£Àü´Þ |
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| PT | pain threshold; parathormone; parathyroid; paroxysmal tachycardia; part time; patient; pericardial t... |
|---|---|
| PTR | patellar tendon reflex; patient termination record; patient to return; peripheral total resistance; ... |
| STOP | Study of Hypertension in the Elderly [Sweden] or Swedish Trial in Old Patients with Hypertension; su... |
| TOP | termination of pregnancy; topoisomerase |
| VTOP | vaginal termination of pregnancy |
| PTC | premature termination codon |
|---|---|
| TOP | termination of pregnancy |
| ERK | 1-extracellular signal-regulated kinase |
| STAT | 2/signal transducer and activator of transcription |
| ASK1 | Apoptosis Signal-regulating Kinase 1 |
| peptide chain termination | The process whereby the last amino acid is added to a polypeptide. This termination is signaled by one of three termination triplets in the mRNA, immediately following the last amino acid codon. (12 Dec 1998) |
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| peptide termination factors | Proteins that are exclusively involved in the termination reactions of protein synthesis on the ribosome. (12 Dec 1998) |
| termination | <molecular biology> Stop of mRNA synthesis (i.e., transcription) at the terminator site Top of protein synthesis (i.e., translation) at the stop codon. (09 Oct 1997) |
| termination codon | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| termination factor | <molecular biology> Any of several proteins in the cytosol that cut a completed polypeptide loose from a ribosome. (13 Jan 1998) |
| termination region | <molecular biology> A DNA sequence that signals the end of transcription. (13 Jan 1998) |
| termination sequence | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| COOH-terminal signal transamidase | <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor Registry number: EC 2.3.2.- Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase (26 Jun 1999) |
| signal | 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton) 2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service. Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous. Origin: From signal, n., cf. F. Signale. Source: Websters Dictionary (01 Mar 1998) |
| signal detection (psychology) | A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment. (12 Dec 1998) |
| signal node | A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion. Synonym: jugular gland, Virchow's node. (05 Mar 2000) |
| signal peptidase | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptidase complex | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
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