| ¿µ¹® | alkaline phosphatase | ÇÑ±Û | ¾ËÄ®¸®¼º ÀλêºÐÇØÈ¿¼Ò |
|---|---|---|---|
| ¼³¸í | È¿¼ÒÀÇ ÀÏÁ¾ÀÌ¸ç ¿©·¯ °¡Áö µ¿Á¾È¿¼Ò(±â´ÉÀº °°Áö¸¸ ±¸Á¶°¡ ¾à°£¾¿ ´Ù¸¥ È¿¼ÒÇüÅÂ)·Î ½ÅüÀÇ ¿©·¯ ºÎÀ§(ƯÈ÷ »À¿Í °£)¿¡ Á¤»óÀûÀ¸·Î ¸¹ÀÌ Á¸ÀçÇÑ´Ù. °£³» ¾µ°³°üÀÇ ¼¼Æ÷¿¡ ¸¹ÀÌ Á¸ÀçÇϸç, »À¸¦ »ý¼ºÇÏ´Â ¼¼Æ÷ÀÎ »À¸ð¼¼Æ÷(osteoblast)¿¡ ¸¹ÀÌ Á¸ÀçÇÑ´Ù. ±× ¿Ü¿¡µµ ¿©·¯ ±â°ü¿¡ Á¸ÀçÇÑ´Ù. ÀÓ»óÀû ÀÇÀÇ´Â °£°ú »ÀÀÇ º´ Áø´Ü°ú Ä¡·áÈ¿°ú ÆÇÁ¤¿¡ µµ¿òÀ» ÁØ´Ù. °£, ƯÈ÷ °£¿¡¼ ¸¸µé¾îÁø ´ãÁóÀ» »ùâÀÚ±îÁö ¿î¹ÝÇÏ´Â ¾µ°³±æÀÌ ¸·Èù °æ¿ì(¾µ°³°ü³»¿¡ Á¾¾çÀÌ »ý±â°Å³ª ¾µ°³µ¹ÁõÀ¸·Î ÀÎÇØ¼ ¾µ°³°üÀÌ ¸·Èù °æ¿ì)¿¡´Â ¾µ°³³»ÀÇ ¾Ð·ÂÀÌ ³ô¾ÆÁö°í °£³» ¾µ°³°üÀÇ ¼¼Æ÷°¡ ±úÁ® ±× ¼Ó¿¡ µé¾î ÀÖ´ø ¾ËÄ®¸®¼º ÀλêºÐÇØÈ¿¼Ò°¡ Ç÷¾×¼ÓÀ¸·Î ¹æÃâµÇ¾î Ç÷Áß ¾ËÄ®¸®¼º ÀλêºÐÇØÈ¿¼ÒÀÇ ³óµµ°¡ ³ô¾ÆÁø´Ù. ±×¸®°í »ÀÀÇ »ý¼ºÀÌ ¸¹¾ÆÁö´Â ¸ðµç °æ¿ì(¿¹¸¦ µé¸é °ñÀý, Á¾¾ç¿¡ ÀÇÇÑ »ÀÀÇ ÆÄ±«½Ã º¹±¸¸¦ À§Çؼ »ÀÀÇ »ý¼ºÀÌ Áõ°¡ÇÑ´Ù), »À¸ð¼¼Æ÷ÀÇ È°µ¿ÀÌ Áõ°¡µÇ°í »À¸ð¼¼Æ÷ÀÇ È¿¼ÒÀÎ ¾ËÄ®¸®¼º ÀλêºÐÇØÈ¿¼ÒÀÇ È°¼ºµµ ¿ª½Ã Áõ°¡µÈ´Ù. |
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| ¿µ¹® | deoxyribonucleic acid (DNA) | ÇÑ±Û | µ¥¿Á½Ã¸®º¸ÇÙ»ê |
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| ¼³¸í | ÇÙ»êÀÇ ÀÏÁ¾À¸·Î DNA¶ó°íµµ ÇÑ´Ù. DeoxyribonucleotideÀÇ ÁßÇÕüÀ̸ç À¯ÀüÀÚÀÇ ÈÇÐÀû º»Ã¼ÀÌ´Ù. RNA¹ÙÀÌ·¯½º ÀÌ¿ÜÀÇ ¸ðµç »ý¹°Àº DNA¸¦ À¯ÀüÀÚ·Î Áö´Ï°í ÀÖ´Ù. µð¿Á½Ã¸®º¸´ºÅ¬·¹¿ÀƼµå(deoxyribonucleotide)´Â ¿°±â¿Í ´ç(2'-deoxy-D-ribose)°ú ÀλêÀ¸·Î ÀÌ·ç¾îÁø´Ù. ¿°±â´Â ¾Æµ¥´Ñ(adenine), ±¸¾Æ´Ñ(guanine), Ƽ¹Î(thymine)¹× ½ÃÅä½Å(cytosine)ÀÇ 4°¡ÁöÀ̸ç, À̰ÍÀº ´ç¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÎ»ê ¿ª½Ã ´çÀÇ ÇÑ ºÎºÐ¿¡ ºÎÂøµÇ¾î ÀÖ´Ù. ÀÌ deoxyribonucleotideÀÇ ´çÀº ´Ù¸¥ deoxy- ribonucleotideÀÇ ´ç°ú ÀλêÀ» »çÀÌ¿¡ ³õ°í °áÇÕÀ» ÇÏ°Ô µÇ¾î ÇϳªÀÇ ±ä »ç½½À» Çü¼ºÇÏ°Ô µÈ´Ù. Áï ´ç°ú ÀλêÀÌ ÁÖÃàÀÌ µÇ¾î¼ deoxyribonucleotideÀÇ ±ä »ç½½À» ¸¸µç´Ù. ÀÌ deoxyribonucleotideÀÇ »ç½½ µÎ °³´Â °¢°¢ deoxyribonucleotide¿¡ ºÎÂøµÇ¾î ÀÖ´Â ¿°±âµéÀÌ °áÇÕÀ» ÇÏ¿© µÎ °³ÀÇ »ç½½ÀÌ °áÇյǾî ÀÖ´Â ÀÌÁß³ª¼± ±¸Á¶¸¦ ¸¸µé°Ô µÈ´Ù. 4°¡Áö ¿°±â ¾Æµ¥´ÑÀº Ƽ¹Î°ú °áÇÕÀ» Çϰí, ½ÃÅä½Å°ú °áÇÕÀ» ÇÏ°Ô µÈ´Ù. Áï ´ç°ú ÀλêÀº ±ä »ç½½À» ¸¸µå´Â ¿ªÇÒÀ» ÇÏ°í ±ä »ç½½¿¡ ºÎÂøµÈ ¿°±âµéÀÇ °áÇÕ¿¡ ÀÇÇØ¼ µÎ °³ÀÇ ±ä »ç½½Àº ¼·Î ºÙ¾î¼ ÀÌÁß³ª¼± ±¸Á¶¸¦ ¸¸µç´Ù. DNAÀÇ À¯ÀüÁ¤º¸´Â ¿°±â¿¡ ÀúÀåµÈ´Ù. 4°³ÀÇ ¿°±âÀÇ Á¶ÇÕ°ú ¹è¿ÀÌ À¯ÀüÁ¤º¸¸¦ º¸°üÇÏ´Â ÇϳªÀÇ ¾ÏÈ£ ¿ªÇÒÀ» ÇàÇÏ°Ô µÈ´Ù. |
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| ¿µ¹® | retinoic acid | ÇÑ±Û | ·¹Æ¼³ë»ê |
|---|---|---|---|
| ¼³¸í | C20H28O2. ºñŸ¹Î AÀÇ ¾ËÄڿñ⸦ ¾Ëµ¥È÷µå·Î »êÈÇÑ ÈÄ ´Ù½Ã Ä«¸£º¹½Ç»êÀ¸·Î »êÈÇÏ¿© ¾òÀº »ê. ¹ß»ýÁßÀÇ ¼¼Æ÷¿¡ ÀÛ¿ëÇÏ¿© ÇüŸ¦ ¸¸µå´Âµ¥ °ü¿©ÇÑ´Ù. |
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| ¿µ¹® | ribonucleic acid | ÇÑ±Û | ¸®º¸ÇÙ»ê |
|---|---|---|---|
| ¼³¸í | Ribonucleotide monomer·Î ÀÌ·ç¾îÁø ÇÙ»êÀ¸·Î ¿°±â, ´ç, ÀλêÀ¸·Î ±¸¼ºµÈ´Ù. ¿°±â´Â adenine, guanine, cytosine, uracilÀÇ 4Á¾·ù°¡ ÀÖÀ¸¸ç, ´çÀº 5ź´çÀÌ´Ù. RNA´Â DNA¸¦ ÁÖÇüÀ¸·Î ÇÏ¿© »óº¸ÀûÀ¸·Î °áÇÕ, Çü¼ºµÇ¸ç ´Ü¹éÁúÀ» ¸¸µé¾î³»´Â µ¥¿¡ ÀÖ¾î Áß¿äÇÑ ¿ªÇÒÀ» ÇÑ´Ù. Àü·É RNA(mRNA)´Â ´Ü¹éÁú ÇÕ¼º¿¡ ÀÖ¾î °¡Àå ±âº»ÀÌ µÇ´Â DNAÀÇ ¼¿À» »óº¸ÀûÀ¸·Î ¿Å°Ü ¹Þ¾Æ Àü´ÞÇÏ´Â Àü·É±¸½ÇÀ» ÇÏ´Â RNA. ¸®º¸¼Ø RNA(rRNA) ¸®º¸¼ØÀ» Çü¼ºÇÏ´Â 4°¡Áö RNA»ç½½(28S, 18S, 5.8S, 5S·Î ±¸¼º). Àü´Þ RNA(tRNA) ƯÁ¤ ¾Æ¹Ì³ë»êÀ» ÇÑÂÊ ³¡¿¡ Áö´Ï°í »óº¸Àû ¼¿ÀÇ mRNA¿Í ÀϽÃÀû °áÇÕÀ» ÀÌ·ç¸ç ´Ü¹éÁú ÇÕ¼º¿¡ Á÷Á¢ ±â¿©ÇÏ´Â RNAÀÌ´Ù. |
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| ¿µ¹® | acid | ÇÑ±Û | »ê |
|---|---|---|---|
| ¼³¸í | ¹°¿¡ ³ì¾ÒÀ» ¶§ ÀÌ¿ÂÈÇÏ¿© ¼ö¼Ò ÀÌ¿ÂÀ» ¸¸µå´Â ¹°Áú. ½Å¸ÀÀÌ ³ª°í û»ö ¸®Æ®¸Ó½º Á¾À̸¦ ºÓ°Ô º¯È½ÃŰ¸ç ¿°±â¿ÍÀÇ ÁßÈ ¹ÝÀÀ¿¡ ÀÇÇÏ¿© ¹°°ú ¿°À» ¸¸µé°í ÀÌ¿ÂÈ ¿¿¡¼ ¼ö¼Òº¸´Ù ¾Õ¿¡ ÀÖ´Â ±Ý¼Ó°ú ¹ÝÀÀÇÏ¿© ¿°À» ¸¸µé¸é¼ ¼ö¼Ò¸¦ ¹ß»ý½ÃŲ´Ù. ¼ö¼Ò ¿øÀÚ¸¦ ÀÌ¿ÂÈÇÏ´Â ÈûÀÇ °¾à¿¡ µû¶ó °»ê°ú ¾à»êÀ¸·Î ³ª´¶´Ù. |
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| TRAP | Tartrate Resistant Acid Phosphatase |
|---|---|
| TRAP | carpal tunnel syndrome, Raynaud phenomenon, aching muscles, proximal muscle weakness [rheumatic diso... |
| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
| AP | accessory pathway; accounts payable; acid phosphatase; acinar parenchyma; action potential; active p... |
| PAP | pancreatitis-associated protein; Papanicolaou [test]; papaverine; passive-aggressive personality; pa... |
| TrACP | 5-tartrate-resistant acid phosphatase |
|---|---|
| TRAP | Tartrate resistant acid phosphatase |
| TRAPase | Tartrate-resistant acid phosphatase |
| TRAP+ | Tartrate-resistant acid phosphatase-positive |
| FRAP | Fluoride-resistant acid phosphatase |
PDGF (Ç÷¼ÒÆÇ À¯·¡ ¼ºÀå ÀÎÀÚ
| tartrate-resistant acid phosphatase | <biochemistry, enzyme> Acid phosphatase is present in bone, prostate, platelets, erythrocytes and spleen. Osteoclasts contain an isoenzyme that is resistant to tartrate, whereas, the isoenzyme in the prostate is sensitive. Tartrate-resistant acid phosphatase is elevated in the serum of patients with primary hypoparathyroidism, Paget disease, vertebral osteoporosis, T-cell lymphoma and in women after oophorectomy. Oestrogen replacement in osteoporotic postmenopausal women is associated with a decrease in tartrate-resistant acid phosphatase of 70% over 3 to 6 months. Acronym: TRAP (16 Dec 1997) |
|---|---|
| acid tartrate | A salt of tartaric acid which contains an acid group still capable of combining with a base; e.g., bitartrate. (05 Mar 2000) |
| potassium acid tartrate | KHC4H4O6;a diuretic and laxative. Synonym: cream of tartar, potassium acid tartrate. (05 Mar 2000) |
| noradrenaline acid tartrate | norepinephrine bitartrate |
| antibiotic-resistant | Indicating microorganisms that continue to multiply although exposed to antibiotic agents. (05 Mar 2000) |
| vancomycin resistant enterococcus | A form of intestinal bacteria (formerly classed under streptococcus faecalis) which is not sensitive to the big gun antibiotic, vancomycin. This organism is usually only fatal in those who are, for reasons of age or infirmity, immunosuppressed. The pathology of the illness is exacerbated when haemosepsis (blood-stream infection) develops. (09 Oct 1997) |
| vasopressin-resistant diabetes | Diabetes insipidus due to inability of the kidney tubules to respond to antidiuretic hormone; X-linked inheritance, with full expression in males and partial defect in heterozygous females. Synonym: vasopressin-resistant diabetes. (05 Mar 2000) |
| vitamin d-resistant rickets | <radiology> X-linked recessive, defect in renal tubular resorption of phosphate, presents at 1 yr, progressive limb deformities X-ray: less severe changes than other rickets, presents later Differential diagnosis features: family hx, normal serum calcium, marked hypophosphataemia (decreased PO4), no secondary hyperparathyroidism (12 Dec 1998) |
| resistant | Making or having powers of resistance, resisting. (18 Nov 1997) |
| resistant ovary syndrome | <syndrome> An obsolete term for amenorrhoea associated with hypergonadotrophism and normal ovarian follicles. Synonym: resistant ovary syndrome. Origin: after the surname of the first reported patient (05 Mar 2000) |
| multiple drug resistant tuberculosis | A strain of TB that does not respond to two or more standard anti-TB drugs. MDR-TB usually occurs when treatment is interrupted thus allowing mutations in the organism to occur that confer drug resistance. (09 Oct 1997) |
| drug resistant | Unresponsive to the desired effects of drugs or other therapy for example: irradiation cytotoxic agents or hormones. Drug resistance of cells within tumours is probably the major cause of treatment failure. (16 Dec 1997) |
| tuberculosis, multidrug-resistant | Tuberculosis resistant to chemotherapy with two or more antitubercular agents. The problem of resistance is particularly troublesome in tuberculosis as an opportunistic disease in HIV infection. (12 Dec 1998) |
| ketosis-resistant diabetes | Type II or adult onset diabetes mellitus, in which episodes of ketoacidosis rarely occur. (05 Mar 2000) |
| acid phosphatase | <enzyme> An enzyme that catalyses the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. Chemical name: Orthophosphoric-monoester phosphohydrolase (acid optimum) Registry number: EC 3.1.3.2 (12 Dec 1998) |
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