| MIg | malaria immunoglobulin; measles immunoglobulin; membrane immunoglobulin |
|---|---|
| Ly | a T-cell antigen used for grouping T-lymphocytes into different classes |
| AH | 1) Atrial Hypertrophy 2) Anti-Hyaluronidase 3) Amyloid imm... |
| AL | Amyloid immunoglobulin Light chain protein |
| TBII | TSH Binding Inhibiting(= Inhibition) Immunoglobulin |
| Ig | Anti-immunoglobulin |
|---|---|
| anti-Ig | Anti-immunoglobulin |
| anti-IgE | Anti-immunoglobulin E |
| HIgG | Human immunoglobulin G |
| IVIG | IV immunoglobulin G |
| immunoglobulin class switching | Gene rearrangement of the b-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. (12 Dec 1998) |
|---|---|
| antigenic switching | <immunology> The process by which a pathogenic microbe's genetic structure is altered tochange its surface antigens inorder to avoid being detected by the host's immune system. (09 Oct 1997) |
| magnetic switching | <radiobiology> The use as switches of saturable inductors for producing high power pulses without electrical arcs. This is a principal technology for extending single-shot accelerators in light-ion-beam-driven inertial confinement fusion to repetitively pulsed devices for possible reactors. Three terawatt, 200 KJ magnetic switches have been developed for fusion drivers at Sandia National Laboratories. (Info from the 1985 OSTI Glossary of Fusion Energy, may be out of date.) (09 Oct 1997) |
| switching | 1. Making a shift or exchange. 2. The movement of a defined region of DNA within a genome. Class switching, a change in the expression of the C region of an immunoglobulin heavy chain. (05 Mar 2000) |
| switching site | The break point in a DNA sequence at which a gene segment unites with another gene segment, as in the production of the immunoglobulins. (05 Mar 2000) |
| isotype switching | <immunology> The switch of immunoglobulin isotype that occurs, for example: as the immune response progresses (IgM to IgG). The switch from IgM to IgG involves only the constant region of the heavy chains (from _ to _), the light chain and variable regions of the heavy chain remaining the same and involves the switch regions, upstream (on the 5'side) of the constant region genes, at which recombination occurs. Similarly, IgM and IgD with the same variable region of the heavy chain, but with different heavy chain constant regions (_ and _), seem to coexist on the surface of some lymphocytes. (18 Nov 1997) |
| anti-D immunoglobulin | rHo(D) immune globulin |
| rabies immunoglobulin | rabies immune globulin (human) |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| Rho(D) immunoglobulin | rHo(D) immune globulin |
| chickenpox immunoglobulin | chickenpox immune globulin (human) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
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