| SET | surrogate embryo transfer; systolic ejection time |
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| SM | Master of Science; sadomasochism; self-monitoring; silicon microphysiometer; simple mastectomy; skim... |
| Gm | an allotype marker on the heavy chains of immunoglobins |
| mar | margin; marker [chromosome] |
| mar(X) | marker X [chromosome] |
| SEB | Surrogate endpoint biomarker |
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| MAS | Marker Assisted Selection |
| OMP | Olfactory Marker Protein |
| SMP 30 | Senescence marker protein 30 |
| SMC | Supernumerary Marker Chromosome |
| surrogate marker | <biology> A laboratory measurement of biological activity within the body that indirectly indicates the effect of treatment on disease state. CD4 cell counts and viral load are examples of surrogate markers in HIV infection. (19 Jan 1998) |
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| mother surrogate | One who substitutes for or takes the place of the mother. (05 Mar 2000) |
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| surrogate | 1. A person who functions in another's life as a substitute for some third person such as a relative who assumes the nurturing and other responsibilities of the absent parent. 2. A person who reminds one of another person so that one uses the first as an emotional substitute for the second. Origin: L. Surrogo, to put in another's place (05 Mar 2000) |
| surrogate mother | A woman who has been contracted with to carry a pregnancy for another woman or couple. (05 Mar 2000) |
| surrogate mothers | Women who allow themselves to be impregnated with the understanding that the offspring are to be given over to the parents who have commissioned the surrogate. (12 Dec 1998) |
| allotypic marker | Synonym: allotype. (05 Mar 2000) |
| genetic marker | A gene which has an easily identifiable phenotype so that one can tell apart cells or individuals which have the gene and those which do not have it. Such a gene can also be used as a probe to mark cell nuclei or chromosomes so that they can easily be isolated or identified from other nuclei or chromosomes later. (09 Oct 1997) |
| marker | An identifiable physical location on a chromosome (for example, restriction enzyme cuttingsite, gene) whose inheritance can bemonitored. Markers can beexpressed regions of DNA (genes) or some segment of DNA with no knowncoding function but whose pattern of inheritance can be determined. See: restriction fragment length polymorphism. (09 Oct 1997) |
| marker chromosome | An abnormal chromosome that is distinctive in appearance but not fully identified. For example, the fragile x chromosome was once called the marker x. (12 Dec 1998) |
| marker enzyme | <enzyme> An enzyme that is used to identify a specific cell type, cell organelle, or cell component. (05 Mar 2000) |
| marker gene | Gene that confers some readily detectable phenotype on cells carrying the gene, either in culture or in transgenic or chimeric organisms. Gene could be an enzymic reporter gene, a selectable marker conferring antibiotic resistance or a cell membrane protein with a characteristic epitope. (18 Nov 1997) |
| marker locus | A locus on a chromosome or in a stretch of DNA that can be identified (e.g., a restriction fragment length polymorphism) and can serve in linkage analysis and in the isolation of a disease gene. See: linkage marker. (05 Mar 2000) |
| marker, object | <microscopy> A small abrasive stylus, set in a rotating holder mounted on the lower end of the drawtube. The desired part of the specimen is placed in the centre of the field, and the abrasive point is pressed against the slide or cover, and rotated. It describes a tiny circle around the desired object field. (05 Aug 1998) |
| marker trait | A trait that may be of little importance in itself but which by association, linkage, or other means facilitates the detection, anticipation, or understanding of a disease or (for genetic diseases) the localization of the causative gene on the karyotype. (05 Mar 2000) |
| cell marker | <cell biology> Biochemical or genetic characteristics which distinguish and discriminate between different cell types. (26 Mar 1998) |
| cell surface marker | <cell biology> Any molecule characteristic of the plasma membrane of a cell or in some cases of a specific cell type. 5' nucleotidase and Na/K ATPase are often used as plasma membrane markers. (26 Mar 1998) |
| surrogate marker |
Laboratory tests that may predict a patient's clinical outcome or indicate whether a drug is effective without having to rely on the traditional clinical endpoints of death or development of a major opportunistic infection. Surrogate markers under study in HIV disease include CD4 counts, CD4/CD8 cell ratios, and viral load.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
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| surrogate marker |
Something that indirectly reflects the patient's current clinical condition. For example, the number of T cells tells us something about how much damage HIV has done, but it is not a direct measure of how much virus is present.
Ãâó: www.thebody.com/hivnews/aidscare/dec97/pullout.htm...
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| surrogate marker |
an indirect measure of disease progression. In HIV disease, the number of CD4+ T cells per cubic millimeter of blood is often used as a surrogate marker.
Ãâó: www.opendoorclinic.org/hivglossary.htm
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| surrogate marker |
A measurement of a drug's biologic activity that substitutes for a clinical endpoint such as death or pain relief. Source: Applied Clinical Trials/Advanstar. Click for their site: www.advanstar. ...
Ãâó: www.biotechmedia.com/definitions-s.html
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