| Ts cell | suppressor T cell(= T8 cell) |
|---|---|
| CD8 | HIV suppressor cell count |
| H/S | helper-suppressor [ratio] |
| NSC | neurosecretory cell; no significant change; nonservice connected; nonspecific suppressor cell; norma... |
| SAD | Scale of Anxiety and Depression; seasonal affective disorder; Self-Assessment Depression [scale]; se... |
| GSE | genetic suppressor element |
|---|---|
| KSR | Kinase Suppressor of Ras |
| MNSF | Monoclonal non-specific suppressor factor |
| NS | Natural suppressor |
| SIRS | Soluble immune response suppressor |
| suppressor | A compound that suppresses the effects of mutation or suppresses what would be a normal course of events. (05 Mar 2000) |
|---|---|
| suppressor cell | <immunology> Lymphocyte class of cells suppressing T or B antigen dependent responses. (18 Nov 1997) |
| suppressor cells | Cells of the immune system that inhibit or help to terminate an immune response, e.g., suppressor macrophages and suppressor T-cells. Synonym: cytotoxic cell. (05 Mar 2000) |
| suppressor factor | <immunology> Factors released by T suppressor cells. See: suppressor mutation, ochre suppressor, opal suppressor. (19 Jan 1998) |
| suppressor factors, immunologic | Proteins, protein complexes, or glycoproteins secreted by suppressor T-cells that inhibit either subsequent T-cells, B-cells, or other immunologic phenomena. Some of these factors have both histocompatibility (I-j) and antigen-specific domains which may be linked by disulfide bridges. They can be elicited by haptens or other antigens and may be mass-produced by hybridomas or monoclones in the laboratory. (12 Dec 1998) |
| suppressor mutation | <molecular biology> Mutation that alleviates the effect of a primary mutation at a different locus. May be through almost any mechanism that can give a primary mutation, but perhaps the most interesting class are the amber and ochre supressors, where the anticodon of the tRNA is altered so that it mis reads the termination codon and inserts an amino acid, preventing premature termination of the peptide chain. (18 Nov 1997) |
| suppressor T-cell | <immunology> See T-cells. (18 Nov 1997) |
| suppressor tRNA | The tRNA associated with a suppressor mutation. (05 Mar 2000) |
| suppressor-sensitive mutant | A conditionally lethal, host range, bacteriophage mutant that produces nonsense codons and can replicate only in a host bacterium able to translate the nonsense codon; the mutation's effects are lethal (i.e., prevent replication of the virus) in a bacterium without such a suppressor mechanism. (05 Mar 2000) |
| amber suppressor | <molecular biology> A tRNA molecule which suppresses amber mutations because it has mutated to recognise the amber codon UAG (which normally signals that the translation of mRNA into an amino acid chain should stop) as a signal for inserting whatever amino acid it carries into the chain. As a result, it can prevent the amino acid chain from ending before it is completed. (09 Oct 1997) |
|---|---|
| genes, suppressor | Genes that inhibit expression of a previous mutation. They allow the wild-type phenotype to be wholly or partially restored. (12 Dec 1998) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| ochre suppressor | A gene that codes for an altered tRNA so that its anticodon can recognise the ochre codon and thus allows the continuation of protein synthesis. A suppressor of an ochre mutation is a tRNA that is charged with the amino acid corresponding to the original codon or a neutral substitute. Ochre suppressors will also suppress amber codons. (18 Nov 1997) |
| opal suppressor | <molecular biology> A gene that codes for an altered tRNA so that its anticodon can recognise the opal codon and thus allows the continuation of protein synthesis. A suppressor of an opal mutation is a tRNA that is charged with the amino acid corresponding to the original codon or a neutral substitute. Some eukaryote cells normally synthesise opal suppressor tRNAs. The function of these is not clear and they usually do not prevent normal termination of protein synthesis at an opal codon. (18 Nov 1997) |
| T-lymphocytes, suppressor-effector | Subpopulation of CD8+ T-lymphocytes which suppress antibody production or inhibit cellular immune responses. Suppressor-effector cells execute the message received from suppressor-inducer cells (T-lymphocytes, suppressor-inducer). (12 Dec 1998) |
| T-lymphocytes, suppressor-inducer | Subpopulation of CD4+ lymphocytes which induce CD8+ suppressor T-cells (T-lymphocytes, suppressor-effector) to suppress antibody production by B-cells. They also stimulate other cellular immune responses. (12 Dec 1998) |
| T suppressor cell | <haematology, immunology> Set of T lymphocytes (usually CD8) specifically involved in suppressing B-cell differentiation into antibody secreting cells. There may also be T suppresors of T-cell functions. (18 Nov 1997) |
| t-suppressor cell | A type of immune cells, also called t8 cells, these cells close down the immune response after it has destroyed invading organisms. T8 cells are sensitive to high concentrations of circulating lymphokine hormones and release their own lymphokines after an immune response has achieved its goal, signalling all other participants to cease their attack. Some memory B-cells remain to ward off a repeat attack by the invading organism. (12 Dec 1998) |
| tumour suppressor | <molecular biology, oncology> A gene that encodes a product that normally negatively regulates the cell cycle and that must be mutated or otherwise inactivated before a cell can proceed to rapid division. Examples: p53, RB retinoblastoma), WT 1 (Wilm's tumour), DCC (deleted in colonic carcinoma), NF 1 (neurofibrosarcoma) and APC adenomatous polyposis coli). (18 Nov 1997) |
Synonyms : Factors, Immunologic Suppressor, Factors, T Suppressor, Suppressor Factor (SF4), T Cell Suppressor Factors, Factors, Suppressor T-Cell, Factors, T-Cell Suppressive, Factors, T-Suppressor, Suppressive Factors, T-Cell, Suppressor Factors, T, T Suppressor Factors
Synonyms : SOCS Proteins, Suppressors of Cytokine Signaling Proteins
| suppressor gene |
suppressor: a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
Ãâó: wordnet.princeton.edu/perl/webwn
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|---|---|
| suppressor T cell |
Regulatory T cells (also known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and there by maintain immune system homeostasis and tolerance to self. The existence of a dedicated population of suppressor T cells was the subject of significant controversy among immunologists for many years. ...
Ãâó: en.wikipedia.org/wiki/Suppressor_T_cell
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| suppressor mutation |
A mutation that partially or completely cancels the phenotypic effect of another mutation.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E22.htm
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| suppressor mutation |
A secondary mutation that restores function lost due to mutation at another site.
Ãâó: www.genpromag.com/Glossary~LETTER~S.html
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| suppressor gene |
A gene that reverses the effect of a mutation in another gene.
Ãâó: www.genpromag.com/Glossary~LETTER~S.html
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| suppressor | an electrical device for suppressing unwanted currents |
|---|---|
| suppressor | a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene) |
| suppressor | someone who suppresses |
| suppressor | a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene) |
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