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| SSD | shaded surface display; single saturating dose; Social Security disability; source-skin distance; so... |
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| MD | Doctor of Medicine [Lat. Medicinae Doctor]; magnesium deficiency; main duct; maintenance dose; major... |
| GDH | glucose dehydrogenase; glutamate dehydrogenase; glycerophosphate dehydrogenase; glycol dehydrogenase... |
| SDA | right sacroanterior [fetal position] [Lat. sacrodextra anterior]; sialodacryoadenitis; specific dyna... |
| LAD | lactic acid dehydrogenase; left anterior descending [artery]; left axis deviation; leukocyte adhesio... |
| SSADH | Succinic semialdehyde dehydrogenase |
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| SDH | Succinic dehydrogenase |
| GSA | Glutamate-1-semialdehyde |
| GSA | Guanidino succinic acid |
| G6PD | Glucose-6-Phosphate dehydrogenase deficiency |
| acetoacetyl-succinic thiophorase | <enzyme> An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues. Synonym: 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase. (05 Mar 2000) |
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| alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound b hydrolase (26 Jun 1999) |
| alpha-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound a hydrolase (26 Jun 1999) |
| succinic | <chemistry> Pertaining to, or derived from, amber; specif, designating a dibasic acid, CH.(COH), first obtained by the dry distillation of amber. It is found in a number of plants, as in lettuce and wormwood, and is also produced artificially as a white crystalline substance having a slightly acid taste. Origin: Cf. F. Succinique. See Succinate. Source: Websters Dictionary (01 Mar 1998) |
| succinic acid | <chemical> A water-soluble, colourless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. Pharmacological action: anti-ulcer agents, radiation-protective agents. (12 Dec 1998) |
| succinic acid cycle | A series of oxidation reduction reactions in which succinic acid and other 4-carbon atoms acids (fumaric, malic, oxaloacetic) take part in the oxidation of pyruvic acid as part of the tricarboxylic acid cycle. See: dicarboxylic acid cycle. (05 Mar 2000) |
| succinic acids | A class of dicarboxylic acids with the general structure of butanedioic acid (succinic acid). They are used in perfumery and as a chemical intermediate in medicine. (12 Dec 1998) |
| succinic anhydrides | A subclass of anhydrides with the general structure of dihydrofurandione. They can be substituted on any carbon atom. They modify and inhibit proteins and enzymes and are used in the acylation of amino- and hydroxyl groups. (12 Dec 1998) |
| succinic thiokinase | A ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA, a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle. Synonym: succinic thiokinase, succinyl-CoA ligase. (05 Mar 2000) |
| glucose-6-dehydrogenase deficiency | <biochemistry> An inherited condition that results in a deficiency in glucose-6-phosphate dehydrogenase. Particular drugs (sulphonamides) can exacerbate this problem. The result is haemolytic anaemia. (27 Sep 1997) |
| glucose-6-phosphate dehydrogenase deficiency | A deficiency of glucose-6-phosphate dehydrogenase, an enzyme important for maintaining cellular concentrations of reduced nucleotides. Deficiency of this enzyme is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The gene for this enzyme is on the X chromosome and there are various polymorphic forms. Males with the enzyme deficiency develop haemolytic anaemia when red blood cells are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. It can also cause anaemia of the newborn, and chronic nonspherocytic haemolytic anaemia. Inheritance: X-linked. (12 Sep 2002) |
| glucosephosphate dehydrogenase deficiency | A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of enzyme activity in erythrocytes, leading to haemolytic anaemia. (12 Dec 1998) |
| pyruvate dehydrogenase complex deficiency | An autosomal recessive pyruvate metabolism disorder resulting from deficient enzyme activity in one of several proteins of pyruvate dehydrogenase complex, resulting in deficiency of acetyl CoA. Deficiency in acetyl CoA product reduces the synthesis of acetylcholine, thereby causing neurological abnormalities. Clinical presentations include lactic acidosis, mental retardation, and ataxia. (12 Dec 1998) |
| deficiency, glucose-6-phosphate dehydrogenase | Deficiency of G6PD is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anaemia due to breakup of their red blood cells when they are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. (12 Dec 1998) |
| abdominal muscle deficiency syndrome | <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear. (05 Mar 2000) |
| succinic semialdehyde dehydrogenase deficiency |
an autosomal recessive aminoacidopathy caused by deficiency of the enzyme succinate semialdehyde dehydrogenase. The resulting increase in γ-aminobutyric acid and γ-hydroxybutyric acid causes mental retardation, hypotonia, and ataxia. Called also γ- or 4-hydroxybutyricaciduria.
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