| ¿µ¹® | rebound phenomenon | ÇÑ±Û | ¹Ý¹ßÇö»ó, ¹Ýµ¿Çö»ó |
|---|---|---|---|
| ¼³¸í | ¼Ò³ú ±â´ÉÀå¾Ö¿¡¼ »çÁöÀÇ ´ëÇ×±ÙÀ° »çÀÌÀÇ ÇùÁ¶¼º »ó½ÇÀÇ Â¡Èķμ, ȯÀÚ¿¡°Ô ¾çÆÈÀ» ¼öÆòÀ¸·Î »¸°Ô ÇÏ°í ±× ÆÈÀ» °ÇÏ°Ô Ä¡¸é Á¤»óÀÎ °æ¿ì´Â °ð ¿ø»óÀ¸·Î ¿Ã¸®´Âµ¥ ºñÇÏ¿© ȯÀÚ¿¡ À־ ¿øÀ§Ä¡·Î µ¹¾Æ¿À´Â µ¥ ¸î ¹øÀ̳ª ¶³°Ô µÈ´Ù. |
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| ¿µ¹® | steroid | ÇÑ±Û | ½ºÅ×·ÎÀ̵å |
|---|---|---|---|
| ¼³¸í | Hydrogenated cyclopentanoperhydrophenanthrene ring systemÀ¸·Î ±¸¼ºµÈ ºÐÀÚ. »ýü³»¿¡¼ Áß¿äÇÑ ½ºÅ×·ÎÀ̵å´Â ºÎ½Å°ÑÁú¿¡¼ »ý¼ºµÇ´Â ½ºÅ×·ÎÀ̵å È£¸£¸óÀÌ¸ç ´ç´ë»ç¿¡ °ü¿©ÇÏ´Â ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å(glucocorticoid), ¿°·ù´ë»ç(ÀÎü³» Á¸ÀçÇÏ´Â ¿°ºÐ¼ººÐ(NaCl, KCl, NaOH µî)À» Á¶ÀýÇÏ´Â ´ë»ç)¿¡ °ü¿©ÇÏ´Â ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å(mineralocorticoid), ¼ºÈ£¸£¸ó(ÀÎüÀÇ ¼º¹ß´Þ¿¡ °ü¿©)ÀÇ ¼¼ °¡ÁöÀÌ´Ù. ½ºÅ×·ÎÀ̵å È£¸£¸óÀº ºÎ½ÅÇÇÁú¿¡¼ ÄÝ·¹½ºÅ×·ÑÀ» Àç·á·Î ÇÏ¿© º¹ÀâÇÑ ÇÕ¼º´Ü°è¸¦ °ÅÃÄ ÇÕ¼ºµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â ³úÇϼöü¿¡¼ ºÐºñµÇ´Â ºÎ½Å°ÑÁúÀÚ±Ø È£¸£¸ó(ACTH)¿¡ ÀÇÇØ »ý¼º°ú ºÐºñ°¡ ÀÌ·ç¾îÁö³ª ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å´Â ·¹´Ñ-¾ÈÁö¿ÀÅٽŰè(½ÅÀå¿¡¼ ÀÎü³» ¿°ºÐÀÌ ºÎÁ·½Ã ·¹´ÑÀÌ ºÐºñµÇ°í, ÀÌ ÀÚ±ØÀº ºÎ½ÅÀ¸·Î ÀüÇØÁ® ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÎ ¾ÈÁö¿ÀÅÙ½ÅÀ» ºÐºñÇÏ°Ô µÊ)ÀÇ Àڱؿ¡ ÀÇÇØ ºÐºñµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â transcortin°ú °áÇÕÇÏ¿© ¿î¹ÝµÇ¸ç ¹Ý°¨±â´Â Çѽð£ Á¤µµÀ̳ª ¿°·ùÄÚ¸£Æ¼ÄÚÀ̵å´Â ´ëºÎºÐÀÌ ´Ü¹éÁú°ú °áÇÕÇÏÁö ¾Ê°í À¯¸®ÇüÀ¸·Î ³²¾ÆÀÖ¾î ¹Ý°¨±â´Â 20ºÐ¿¡ ºÒ°úÇÏ´Ù. À̵éÀÌ °£¿¡ µµ´ÞÇϸé glucuronic acid¿¡ °áÇÕÇÏ¿© ¹è¼³µÈ´Ù. |
||
| RT | Rebound Tenderness |
|---|---|
| T/RT | Tenderness/Rebound Tenderness |
| PIR | postinhibition rebound; protein identification resource |
| CREST Syndrome | 1. Calcinosis cutis 2. Raynaud's phenomenon 3. Esophageal ... |
| CRST Syndrome | 1. Calcinosis 2. Raynaud's Phenomenon 3. Sclerodactyly ... |
| PIR | Postinhibitory rebound |
|---|---|
| PRP | Primary Raynaud's Phenomenon |
| RP | Raynaud Phenomenon |
| 3 beta-HSD | 3 beta hydroxy steroid dehydrogenase |
| 3 beta-HSD | 3 beta-hydroxy-steroid dehydrogenase/delta 5-delta 4 isomerase |
| rebound phenomenon | Generally, any phenomenon in which a variable that has been displaced from its normal state by a disturbing influence temporarily deviates from normal in the opposite direction when the disturbing influence is suddenly removed, before finally stabilizing at its normal state, i.e., a phenomenon involving undershoot; e.g., the subsequent hypoglycaemia that may follow injection of glucose, because the initial hyperglycaemia caused excessive secretion of insulin. Synonym: Stewart-Holmes sign (05 Mar 2000) |
|---|---|
| rebound | Just like a rebound in basketball when the ball reverses its course and bounces back off the backboard, in medicine a rebound is a reversal of response upon withdrawal of the stimulus. (12 Dec 1998) |
| rebound effect | The characteristic of a drug to produce reverse effects when either the effect of the drug has passed or when the patient no longer responds to the drug. (18 Nov 1997) |
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 15-beta-hydroxylase | <enzyme> Contains p-450 and ferredoxin; from bacillus megaterium Registry number: EC 1.14.99.- Synonym: cytochrome p-450 15 beta-hydroxylase, p-450 (15-beta), steroid-15 beta-monooxygenase, cytochrome p-450meg, cytochrome p4502c12, cyp2c12 protein (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
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