| 영문 | steroid | 한글 | 스테로이드 |
|---|---|---|---|
| 설명 | Hydrogenated cyclopentanoperhydrophenanthrene ring system으로 구성된 분자. 생체내에서 중요한 스테로이드는 부신겉질에서 생성되는 스테로이드 호르몬이며 당대사에 관여하는 글루코코르티코이드(glucocorticoid), 염류대사(인체내 존재하는 염분성분(NaCl, KCl, NaOH 등)을 조절하는 대사)에 관여하는 광물코르티코이드(mineralocorticoid), 성호르몬(인체의 성발달에 관여)의 세 가지이다. 스테로이드 호르몬은 부신피질에서 콜레스테롤을 재료로 하여 복잡한 합성단계를 거쳐 합성된다. 글루코코르티코이드는 뇌하수체에서 분비되는 부신겉질자극 호르몬(ACTH)에 의해 생성과 분비가 이루어지나 광물코르티코이드는 레닌-안지오텐신계(신장에서 인체내 염분이 부족시 레닌이 분비되고, 이 자극은 부신으로 전해져 광물코르티코이드인 안지오텐신을 분비하게 됨)의 자극에 의해 분비된다. 글루코코르티코이드는 transcortin과 결합하여 운반되며 반감기는 한시간 정도이나 염류코르티코이드는 대부분이 단백질과 결합하지 않고 유리형으로 남아있어 반감기는 20분에 불과하다. 이들이 간에 도달하면 glucuronic acid에 결합하여 배설된다. |
||
| 영문 | purpura | 한글 | 자색반증 |
|---|---|---|---|
| 설명 | 피부내의 출혈로 인하여, 피부 표피를 통하여 쉽게 보이는 자홍색 혹은 적갈색 반점을 특징으로 하는 일련의 질환을 총칭하는 용어이다. 대개 홍반과 구별해야 하는 데 홍반은 피부밑의 혈관이 팽창하여 붉게 보이는 현상으로 투명한 자를 이용하여 피부를 눌러서 관찰해보면 쉽게 구별이 가능하다. 이때 홍반은 붉은 색이 없어지지만, 자반은 붉은 색이 없어지지 않는다. |
||
| ITP | idiopathic thrombocytopenic purpura; immune thrombocytopenia; immunogenic thrombocytopenic purpura; ... |
|---|---|
| ATP | 1) Adenosine Tri-Phosphate 2) Autoimmune Thrombocytopenic Purpura |
| HSP | Henoch Schonlein Purpura |
| ITP | Idiopathic(Immune) Thrombocytopenic Purpura |
| PTP | Post-Transfusion Purpura |
| AITP | Autoimmune thrombocytopenic purpura |
|---|---|
| ATP | Autoimmune thrombocytopenic purpura |
| HSP | Henoch Schonlein Purpura |
| HSPN | Henoch-Schoenlein purpura nephritis |
| ITP | Idiopathic thrombocytopenic purpura |
| acute vascular purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
|---|---|
| allergic purpura | Nonthrombocytopenic purpura due to sensitization to foods, drugs, and insect bites. Synonym: anaphylactoid purpura. (05 Mar 2000) |
| anaphylactoid purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| autoimmune thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| Waldenstrom's purpura | <haematology> A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen. (27 Sep 1997) |
| Henoch-Schonlein purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| Henoch's purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| Schonlein's purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| psychogenic purpura | <syndrome> A condition, usually occurring in women, in which the individual bruises easily (purpura simplex) and the ecchymoses tend to enlarge and involve adjacent tissues, resulting in pain in the affected parts; so-called because similar lesions are produced by inoculation of the individual's blood or various components of red blood cells and it is thought to be a form of localised autosensitization, although no specific antibodies have been demonstrable; in some individuals, there seems to be a psychogenic mechanism. Synonym: Gardner-Diamond syndrome, psychogenic purpura. (05 Mar 2000) |
| purpura | <clinical sign, dermatology> A small haemorrhage (up to about 1 cm in diameter) in the skin, mucous membrane or serosal surface, which may be caused by various factors, including blood disorders, vascular abnormalities and trauma. Purpuric lesions may be associated with inflammation, in which case they present as papular purpura or the haemorrhage may not be accompanied by inflammation, in which case they are macular. The term also comprises a group of haemorrhagic diseases characterised by the presence of purpuric lesions, ecchymoses and a tendency to bruise easily, which may be caused by decreased platelet counts, the presence of abnormal platelets, vascular defects or reactions to certain drugs. (15 Dec 1997) |
| purpura, anaphylactoid | See Purpura, Henoch-Schonlein. (12 Dec 1998) |
| purpura angioneurotica | An eruption marked by angioneurotic oedema, petechiae, and hyperesthesia of the skin and gastric mucous membrane. (05 Mar 2000) |
| purpura annularis telangiectodes | Asymptomatic annular lesions, principally of the lower extremities of adolescent males, in which the peripheral portion is composed of purpura or petechiae with brawny staining of haemosiderin deposits and minute telangiectasia. Synonym: Majocchi's disease. (05 Mar 2000) |
| purpura fulminans | A severe and rapidly fatal form of purpura haemorrhagica, occurring especially in children, with hypotension, fever, and disseminated intravascular coagulation, usually following an infectious illness. (05 Mar 2000) |
| purpura haemorrhagica | idiopathic thrombocytopenia purpura |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|