| 영문 | steroid | 한글 | 스테로이드 |
|---|---|---|---|
| 설명 | Hydrogenated cyclopentanoperhydrophenanthrene ring system으로 구성된 분자. 생체내에서 중요한 스테로이드는 부신겉질에서 생성되는 스테로이드 호르몬이며 당대사에 관여하는 글루코코르티코이드(glucocorticoid), 염류대사(인체내 존재하는 염분성분(NaCl, KCl, NaOH 등)을 조절하는 대사)에 관여하는 광물코르티코이드(mineralocorticoid), 성호르몬(인체의 성발달에 관여)의 세 가지이다. 스테로이드 호르몬은 부신피질에서 콜레스테롤을 재료로 하여 복잡한 합성단계를 거쳐 합성된다. 글루코코르티코이드는 뇌하수체에서 분비되는 부신겉질자극 호르몬(ACTH)에 의해 생성과 분비가 이루어지나 광물코르티코이드는 레닌-안지오텐신계(신장에서 인체내 염분이 부족시 레닌이 분비되고, 이 자극은 부신으로 전해져 광물코르티코이드인 안지오텐신을 분비하게 됨)의 자극에 의해 분비된다. 글루코코르티코이드는 transcortin과 결합하여 운반되며 반감기는 한시간 정도이나 염류코르티코이드는 대부분이 단백질과 결합하지 않고 유리형으로 남아있어 반감기는 20분에 불과하다. 이들이 간에 도달하면 glucuronic acid에 결합하여 배설된다. |
||
| ACTH | Adreno-Cortico-Tropic(=Tropin)(or steroid) Hormone |
|---|---|
| 3β-HSD | 3β-Hydroxy-Steroid Dehydrogenase |
| 17-KS | 17-Keto-Steroid |
| 17-KS | 17-Keto-Steroid |
| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
| PPIases | Peptidyl-prolyl isomerases |
|---|---|
| 3 beta-HSD | 3 beta hydroxy steroid dehydrogenase |
| 3 beta-HSD | 3 beta-hydroxy-steroid dehydrogenase/delta 5-delta 4 isomerase |
| AAS | Anabolic androgenic steroid |
| NSAID | Non Steroid Anti-Inflammatory Drugs |
| steroid isomerases | <enzyme> Enzymes that catalyze the transposition of double bond(s) in a steroid molecule. Registry number: EC 5.3.3.- (12 Dec 1998) |
|---|
| aldose-ketose isomerases | <enzyme> Enzymes that catalyze the interconversion of aldoses and ketoses. Registry number: EC 5.3.1 (12 Dec 1998) |
|---|---|
| amino acid isomerases | <enzyme> Enzymes that catalyze either the racemization or epimerization of chiral centres within amino acids or derivatives. Registry number: EC 5.1.1.- (12 Dec 1998) |
| carbon-carbon double bond isomerases | <enzyme> Enzymes that catalyze the shifting of a carbon-carbon double bond from one position to another within the same molecule. Registry number: EC 5.3.3 (12 Dec 1998) |
| cis-trans-isomerases | <enzyme> Enzymes that catalyze the rearrangement of geometry about double bonds. Registry number: EC 5.2 (12 Dec 1998) |
| sulfur-sulfur bond isomerases | <enzyme> Enzymes that catalyze the transposition of a sulfur-sulfur bond. Registry number: EC 5.3.4 (12 Dec 1998) |
| isomerases | <enzyme> A class of enzymes that catalyze geometric or structural changes within a molecule to form a single product. The reactions do not involve a net change in the concentrations of compounds other than the substrate and the product. Registry number: EC 5. (12 Dec 1998) |
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
Synonyms : 3 Ketosteroid Isomerases, 3 Oxosteroid Isomerases, Isomerases, 3-Ketosteroid, Isomerases, 3-Oxosteroid, Isomerases, Steroid
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|