| ¿µ¹® | steroid | ÇÑ±Û | ½ºÅ×·ÎÀ̵å |
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| ¼³¸í | Hydrogenated cyclopentanoperhydrophenanthrene ring systemÀ¸·Î ±¸¼ºµÈ ºÐÀÚ. »ýü³»¿¡¼ Áß¿äÇÑ ½ºÅ×·ÎÀ̵å´Â ºÎ½Å°ÑÁú¿¡¼ »ý¼ºµÇ´Â ½ºÅ×·ÎÀ̵å È£¸£¸óÀÌ¸ç ´ç´ë»ç¿¡ °ü¿©ÇÏ´Â ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å(glucocorticoid), ¿°·ù´ë»ç(ÀÎü³» Á¸ÀçÇÏ´Â ¿°ºÐ¼ººÐ(NaCl, KCl, NaOH µî)À» Á¶ÀýÇÏ´Â ´ë»ç)¿¡ °ü¿©ÇÏ´Â ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å(mineralocorticoid), ¼ºÈ£¸£¸ó(ÀÎüÀÇ ¼º¹ß´Þ¿¡ °ü¿©)ÀÇ ¼¼ °¡ÁöÀÌ´Ù. ½ºÅ×·ÎÀ̵å È£¸£¸óÀº ºÎ½ÅÇÇÁú¿¡¼ ÄÝ·¹½ºÅ×·ÑÀ» Àç·á·Î ÇÏ¿© º¹ÀâÇÑ ÇÕ¼º´Ü°è¸¦ °ÅÃÄ ÇÕ¼ºµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â ³úÇϼöü¿¡¼ ºÐºñµÇ´Â ºÎ½Å°ÑÁúÀÚ±Ø È£¸£¸ó(ACTH)¿¡ ÀÇÇØ »ý¼º°ú ºÐºñ°¡ ÀÌ·ç¾îÁö³ª ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å´Â ·¹´Ñ-¾ÈÁö¿ÀÅٽŰè(½ÅÀå¿¡¼ ÀÎü³» ¿°ºÐÀÌ ºÎÁ·½Ã ·¹´ÑÀÌ ºÐºñµÇ°í, ÀÌ ÀÚ±ØÀº ºÎ½ÅÀ¸·Î ÀüÇØÁ® ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÎ ¾ÈÁö¿ÀÅÙ½ÅÀ» ºÐºñÇÏ°Ô µÊ)ÀÇ Àڱؿ¡ ÀÇÇØ ºÐºñµÈ´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å´Â transcortin°ú °áÇÕÇÏ¿© ¿î¹ÝµÇ¸ç ¹Ý°¨±â´Â Çѽð£ Á¤µµÀ̳ª ¿°·ùÄÚ¸£Æ¼ÄÚÀ̵å´Â ´ëºÎºÐÀÌ ´Ü¹éÁú°ú °áÇÕÇÏÁö ¾Ê°í À¯¸®ÇüÀ¸·Î ³²¾ÆÀÖ¾î ¹Ý°¨±â´Â 20ºÐ¿¡ ºÒ°úÇÏ´Ù. À̵éÀÌ °£¿¡ µµ´ÞÇϸé glucuronic acid¿¡ °áÇÕÇÏ¿© ¹è¼³µÈ´Ù. |
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| ¿µ¹® | hyperthermia, fever | ÇÑ±Û | °í¿ |
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| ¼³¸í | ü¿ÂÁ¶Àý ÁßÃß°¡ ÀÌ»óÀ» ÃÊ·¡ÇØ Ã¼¿ÂÀÌ °è¼Ó »ó½ÂÇÏ¿© Áö¼ÓµÇ°í ÀÖ´Â »óŸ¦ ¸»ÇÑ´Ù. ¿øÀÎÀº ´Ù¾çÇϸç ü¿ÂÁ¶Àý ÁßÃßÀÇ Àå¾Ö(³úÁúȯ), Á¶Á÷Àå¾Ö¿¡ ÀÇÇÑ °ÍÀÌ ÀÖ´Ù. ü¿ÂÀº ÀϹÝÀûÀ¸·Î °Üµå¶ûÀÌ, ÀÔ¾È, °ðâÀÚ¿¡¼ Àç°í, ½Ã°£Àº 10ºÐÀ» ÇÊ¿ä·Î ÇÑ´Ù. Åë»ó 37¡É ÀÌÇÏ(°Üµå¶ûÀÌ)·Î, ÀÔ¾È ¿Âµµ´Â À̺¸´Ù 0.1~0.2¡É ³ôÀ¸¸ç, °ðâÀڿµµ´Â 0.2~0.5¡É ³ô´Ù. °íü¿ÂÁõ¿¡¼µµ µ¿°á°ú À¯»çÇÑ ¼¼Æ÷ º¯È°¡ ³ªÅ¸³´Ù. Áï Ç÷°ü³»ÇǼ¼Æ÷¿¡ ¼Õ»óÀÌ »ý±â°í Ç÷°üÅõ°ú°¡ Áõ°¡µÇ¾î ºÎÁ¾, ¼öÆ÷ µîÀÌ Çü¼ºµÈ´Ù. |
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| ¿µ¹® | dengue fever | ÇÑ±Û | µ±â |
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| ¼³¸í | ÁÖ·Î ¿´ëÁö¹æ¿¡¼ ¹ß»ýÇÏ´Â ¹ÙÀÌ·¯½º¼º ¿º´. 4~8ÀÏÀÇ Àẹ±â¸¦ °ÅÃÄ ±Þ°ÝÇÏ°Ô ¹ß¿Çϰí, °á¸·ÃæÇ÷-°üÀýÅë-±ÙÀ°Åë-¹éÇ÷±¸°¨¼Ò µîÀÇ Áõ»óÀ» º¸ÀδÙ. ´ëºÎºÐ 7~10ÀÏ ÈÄ¿¡´Â ȸº¹µÇ¸ç, »ç¸ÁÇÏ´Â ¿¹´Â µå¹°´Ù. ¹Ì±¹ÀÇ ¼¼±ÕÇÐÀÚÀÎ C.F. Å©·¹À̱״ 1907³â Çʸ®ÇÉ¿¡¼ µ±â¿Àº ¸ð±â¿¡ ÀÇÇØ °¨¿°µÈ´Ù´Â °ÍÀ» È®ÀÎ-º¸°íÇß´Ù. Á¦2Â÷ ¼¼°è´ëÀü Á÷ÈÄ ¹Ì±¹ÀÇ ¼¼±ÕÇÐÀÚ A. B. ¼¼À̺óÀº ±×ÀÇ ¿¬±¸¿¡ ÀÇÇØ µ±â¿ ¹ÙÀÌ·¯½º¿¡´Â ¸é¿ªÇÐÀûÀ¸·Î ³×°¡Áö ÇüÀÌ ÀÖ´Ù°í ¹àÇû´Ù. µ±â¿ ¹ÙÀÌ·¯½º¸¦ ¸Å°³ÇÏ´Â ¸ð±â¿¡´Â ÀÌÁýÆ®½£¸ð±â(Aedes aegypti)¿Í ÈòÁÙ½£¸ð±â(Aedes albopictus)°¡ ¾Ë·ÁÁ® ÀÖ´Ù. ÀÌ º´¿¡ °É¸®°í ³ª¸é ¸é¿ªÀÌ »ý±âÁö¸¸ Áö¼Ó±â°£Àº ºñ±³Àû ª´Ù. |
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| ¿µ¹® | typhus fever | ÇÑ±Û | ¹ßÁøÆ¼Çª½º |
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| ¼³¸í | °í¿°ú ¹ßÁøÀÌ ÁÖÁõ¼¼ÀÎ ¿¼º-±Þ¼ºÀÇ ¹ýÁ¤Àü¿°º´. ¼¼°èº¸°Ç±â±¸(WHO)ÀÇ º¸°Ç±ÔÄ¢¿¡ ÀÇÇÑ ±¹Á¦ °¨½Ã Àü¿°º´ÀÇ ÇϳªÀ̱⵵ ÇÏ´Ù. ¶ÇÇÑ, ÀÌ º´ÀÇ À¯ÇàÀº ÀüÀï°ú °ü°è°¡ ±í¾î ÀüÀïÆ¼Çª½º ¶Ç´Â ±â±Ù¿-±³µµ¼Ò¿ µîÀÇ º°¸íÀÌ ÀÖ´Ù. ±×°ÍÀº ÀÌ º´ÀÇ ¸Å°³°ïÃæÀÎ ¡®¿ÊÀÌ¡¯°¡ ÀÇ·ù³ª ¸öÀÌ ´õ·¯¿ï ¶§ ¹ß»ýÇϱ⠽¬¿ì¹Ç·Î ±º´ë³ª ±³µµ¼Ò, ÀüÀïÅÍ µî ȯ°æÀÌ ³ª»Û °÷¿¡¼ Å©°Ô À¯ÇàÇÏ°Ô µÇ¾ú±â ¶§¹®À̾ú´Ù. Á¦1Â÷ ¼¼°è´ëÀü ´ç½Ã ·¯½Ã¾Æ¿¡¼ ¹ß»ýÇÑ È¯ÀÚÀÇ ¼ö´Â 2,500¸¸ ¸íÀ̳ª µÇ¾ú°í, ¿µ±¹°ú ±âŸ À¯·´¿¡¼µµ ÀüÀï-±â±Ù ¶§¹®¿¡ ÀÌ º´ÀÌ ´ëÀ¯ÇàÇß´ø ±â·ÏÀÌ ÀÖÀ¸¸ç, ÀϺ»¿¡¼µµ Á¦2Â÷ ¼¼°è´ëÀü Á÷ÈÄ¿¡ À¯Çà Çß¾ú´Ù. ¿À´Ã³¯¿¡´Â ¾ÆÇÁ¸®Ä«-À¯·´-¾Æ½Ã¾ÆÀÇ ÀϺÎÁö¿ª¿¡¸¸ Á¸ÀçÇÒ »ÓÀÌ´Ù. º´¿øÃ¼´Â ¸®ÄÉÂ÷ ÇÁ·Î¹ÙÁ¦Å°(Rickettsia prowazeki)·Î ¿ÊÀÌ¿¡ ±â»ýÁõ½ÄÇÏ¿© ¿ÊÀÌÀÇ ºÐº¯°ú ÇÔ²² ¹è¼³µÇ¸é¼ ¿ÊÀ̰¡ ÈíÇ÷Çϱâ À§ÇØ ÇǺο¡ ÁØ »óó³ª »ç¶÷ÀÌ ¼ÕÀ¸·Î ±Ü¾î »ý±ä »óó¸¦ ÅëÇÏ¿© °¨¿°µÈ´Ù. Àẹ±â°£Àº 10~14ÀÏÀÌ¸ç ±ÞÀÛ½º·± ¿ÀÇÑÀ̳ª ÇÔ²² ¹ß¿ÇÏ¿© 3ÀÏ Á¤µµ °æ°úµÇ¸é 40¡É ÀüÈÄÀÇ °í¿ÀÌ ³ª°Ô µÇ°í, µÎÅë-°üÀýÅë-°á¸·ÃæÇ÷ µî°ú Áö¸§ 2mm ¾ÈÆÆÀÇ ºÓ°í ÀÛÀº ÃâÇ÷¼º ¹ßÁøÀÌ ¿Â¸ö¿¡ ¸¹ÀÌ »ý±ä´Ù. Áõ¼¼´Â ÀåÆ¼Çª½º¿Í ºñ½ÁÇϰí, ¹ÙÀÏ-Æç¸¯½º¹ÝÀÀ(Weil-Felix test)À̶ó ÇÏ´Â Ç÷û¹ÝÀÀ¿¡ ÀÇÇØ °¨º°µÈ´Ù. Ŭ·Î¶÷Æä´ÏÄÝÀ̳ª Åׯ®¶ó»çÀÌŬ¸°°èÀÇ Ç×»ý¹°ÁúÀÌ Æ¯È¿¸¦ º¸¿© Ä¡»çÀ²µµ ³·¾ÆÁ³´Ù(20%). ¿¹¹æÀ¸·Î´Â »ìÃæÁ¦·Î ¿ÊÀ̸¦ ±¸Á¦ÇÏ´Â °ÍÀÌ °¡Àå Áß¿äÇϸç, ¹ßÁøÆ¼Çª½º¹é½Å Á¢Á¾µµ À¯È¿ÇÏ´Ù. |
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| ¿µ¹® | scarlet fever | ÇÑ±Û | ¼ºÈ«¿ |
|---|---|---|---|
| ¼³¸í | AÇü¿ëÇ÷»ç½½¾Ë±Õ¿¡ ÀÇÇÑ ¹ýÁ¤ ±Þ¼ºÀü¿°º´ÀÌ´Ù. 5~10¼¼ÀÇ ¼Ò¾Æ¿¡¼ È£¹ßÇÑ´Ù. ÀÛÀº ħ¹æ¿ïÀ» ÅëÇÏ¿© °¨¿°µÇ¸ç Àẹ±âÀÎ 2~4ÀÏÀ» Áö³ª, ÃʱâÁõ»óÀº °í¿, ÀεÎÁ¡¸·, Æíµµ°¡ ÇöÀúÇÏ°Ô ¹ßÀûÁ¾´ëµÈ´Ù. 1~2ÀÏ ÈÄ ºñÀ¶ÇÕ¼ºÀÇ È«»ö¼Ò±¸ÁøÀÌ Àü½Å¿¡ ÃâÇöÇÑ´Ù. ÀÔ ¾ðÀú¸®¿¡´Â ¹ßÁøÀÌ ¾ø°í ÀÔ¼úÁÖÀ§´Â â¹éÇÏ¸ç µþ±âÇô¸¦ º»´Ù. 2~3ÀÏ ÈÄ ¹ßÁøÀÌ »ç¶óÁø´Ù. º´º¯ºÎÀÇ ´ëºÎºÐÀº Ç¥ÃþÀÌ ¹Ú¸®µÇ´Âµ¥ ƯÈ÷ ¼Õ°ú ¹ßÀÇ À¶ÇÕ¼º Å»Çǰ¡ Ư¡ÀÌ´Ù. ÇöÀç´Â °ú°Å¿¡ ºñÇÏ¿© ÈξÀ º´ÀÌ °¡º¿öÁ®¼ ÁßÀÌ¿°, ¹ÙÀ§, ȳó¸²ÇÁÀý¿°µµ µå¹°´Ù. ÀεÎÁ¡¸·¹è¾çÀ¸·Î ±ÕÀ» Áõ¸íÇÏ¿© Áø´ÜÇÑ´Ù. A±º »ç½½¾Ë±Õ°¨¿°ÀÇ ÇÕº´ÁõÀ¸·Î´Â ¸é¿ªº¹ÇÕü¼ºÄáÆÏ¿°°ú ·ù¸¶Æ¼½º¿ÀÌ µÈ´Ù. |
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| HFRS | Hemorrhagic Fever with Renal Syndrome [HP 849-50] = Korean Hemorrhagic Fever &nbs... |
|---|---|
| RF | 1) Renal Failure 2) Rheumatic Fever ? Rheumatic Fever  ... |
| HF | Hageman factor; haplotype frequency; hard filled [capsule]; hay fever; head of fetus; head forward; ... |
| Q fever | query fever |
| SF | Sabin-Feldman [test]; safety factor; salt-free; scarlet fever; screen film; seminal fluid; serosal f... |
| 3 beta-HSD | 3 beta hydroxy steroid dehydrogenase |
|---|---|
| 3 beta-HSD | 3 beta-hydroxy-steroid dehydrogenase/delta 5-delta 4 isomerase |
| AAS | Anabolic androgenic steroid |
| NSAID | Non Steroid Anti-Inflammatory Drugs |
| SBP | Steroid Binding Protein |
| steroid fever | Fever presumably caused by elevated plasma concentrations of certain pyrogenic steroids; can be produced by administration of etiocholanolone. (05 Mar 2000) |
|---|
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
|---|---|
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 15-beta-hydroxylase | <enzyme> Contains p-450 and ferredoxin; from bacillus megaterium Registry number: EC 1.14.99.- Synonym: cytochrome p-450 15 beta-hydroxylase, p-450 (15-beta), steroid-15 beta-monooxygenase, cytochrome p-450meg, cytochrome p4502c12, cyp2c12 protein (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
| steroid 19-hydroxylase | <enzyme> Enzyme from adrenal mitochondria; forms 19-hydroxy-11-deoxycorticosterone Registry number: EC 1.14.13.- Synonym: 19-hydroxysteroid hydroxylase, deoxycorticosterone 11-19-hydroxylase (26 Jun 1999) |
| steroid 21-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal cortex microsomes. It catalyses the 21-hydroxylation of corticosteroids and shows a requirement for NADPH and molecular oxygen. Its deficiency is a cause of adrenogenital syndrome. Chemical name: Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) Registry number: EC 1.14.99.10 (12 Dec 1998) |
| steroid (23R)-hydroxylase | <enzyme> Increased (23r)-hydroxylase activity in patients with cerebrotendinous xanthomatosis, an inborn error of metabolism in bile acid synthesis resulting in (23r)-hydroxylation of bile acids Registry number: EC 1.14.99.- Synonym: bile acid (23r)-hydroxylase, bile alcohol (23r)-hydroxylase (26 Jun 1999) |
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