| SCD | scleroderma; service-connected disability; sickle-cell disease; spinocerebellar degeneration; subacu... |
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| SDSEM | spinocerebellar degeneration-slow eye movements [syndrome] |
| CRD | carbohydrate-recognition domain; chronic renal disease; chronic respiratory disease; child restraint... |
| RD | radial deviation; radiology department; rate difference; Raynaud disease; reaction of degeneration; ... |
| DSCT | dorsal spinocerebellar tract |
| SCD | Spinocerebellar degeneration |
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| DSCT | Dorsal Spinocerebellar Tract |
| SCA1 | Spinocerebellar Ataxia 1 |
| SCA2 | Spinocerebellar Ataxia Type 2 |
| SCA | Spinocerebellar ataxia |
| spinocerebellar degeneration | An autosomal recessive inherited disorder that leads to the progressive dysfunction of the cerebellum, spinal cord and peripheral nerves. Symptoms usually begin in childhood before puberty and consist of an unsteady gait (ataxia), slurred speech (dysarthria) and jerky eye movements (nystagmus). Other findings include kyphoscoliosis, hammer toe, heart disease and high arches. Congestive heart failure is a common complication. There is no known treatment and prognosis is poor. Inheritance: autosomal recessive. (27 Sep 1997) |
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| anterior spinocerebellar tract | A bundle of fibres originating in the base of the posterior horn and zona intermedia throughout lumbosacral segments of the spinal cord, crossing to the opposite side and ascending in a peripheral position in the ventral half of the lateral funiculus. In its ascent through the rhombencephalon, the tract curves sharply dorsalward along the rostral border of the trigeminal motor nucleus, entering the cerebellum in a caudal direction over the dorsal surface of the superior cerebellar peduncle, and terminating as mossy fibres in the granular layer of the cortex of the cerebellar vermis. The bundle conveys proprioceptive and exteroceptive information largely from the opposite lower extremity. Synonym: tractus spinocerebellaris anterior, Gowers' column, Gowers' tract, ventral spinocerebellar tract. (05 Mar 2000) |
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| ventral spinocerebellar tract | A bundle of fibres originating in the base of the posterior horn and zona intermedia throughout lumbosacral segments of the spinal cord, crossing to the opposite side and ascending in a peripheral position in the ventral half of the lateral funiculus. In its ascent through the rhombencephalon, the tract curves sharply dorsalward along the rostral border of the trigeminal motor nucleus, entering the cerebellum in a caudal direction over the dorsal surface of the superior cerebellar peduncle, and terminating as mossy fibres in the granular layer of the cortex of the cerebellar vermis. The bundle conveys proprioceptive and exteroceptive information largely from the opposite lower extremity. Synonym: tractus spinocerebellaris anterior, Gowers' column, Gowers' tract, ventral spinocerebellar tract. (05 Mar 2000) |
| posterior spinocerebellar tract | A compact bundle of heavily myelinated, thick fibres at the periphery of the dorsal half of the lateral funiculus of the spinal cord, originating in the ipsilateral thoracic nucleus (column of Clarke) and ascending by way of the inferior cerebellar peduncle. Terminals end as mossy fibres in the granular layer of the cortex of the cerebellar vermis. The bundle conveys largely proprioceptive information originating from the annulospiral nerve endings surrounding muscle spindles and from Golgi tendon organs. Synonym: tractus spinocerebellaris posterior, Flechsig's tract. (05 Mar 2000) |
| spinocerebellar ataxia | The most common hereditary ataxia, with onset in middle to late childhood, manifested as limb ataxia, nystagmus, kyphoscoliosis, and pes cavus; the major pathological changes are found in the posterior columns of the spinal cord; most often autosomal recessive inheritance. (05 Mar 2000) |
| spinocerebellar tracts | See: anterior spinocerebellar tract, posterior spinocerebellar tract. (05 Mar 2000) |
| adipose degeneration | Abnormal formation of microscopically visible droplets of fat in the cytoplasm of cells, as a result of injury. Synonym: adipose degeneration, steatosis. (05 Mar 2000) |
| adiposogenital degeneration | A disorder characterised primarily by obesity and hypogonadotrophic hypogonadism in adolescent boys; dwarfism is rare, and when present is thought to reflect hypothyroidism. Visual loss, behavioural abnormalities, and diabetes insipidus may occur. Frohlich's syndrome often is used synonymously for this disorder, although the original case involved a pituitary tumour; most cases are thought to result from hypothalamic dysfunction in areas regulating appetite and gonadal development. The most common causes are pituitary and hypothalamic neoplasms. Synonym: adiposis orchica, adiposogenital degeneration, adiposogenital dystrophy, adiposogenital syndrome, hypophysial syndrome, hypothalamic obesity with hypogonadism. Origin: L. Fr. G. Dys-, bad, + trophe, nourishment (05 Mar 2000) |
| age-related macular degeneration | A common macular degeneration beginning with drusen of the macula and pigment disruption and sometimes leading to severe loss of central vision. (05 Mar 2000) |
| albuminous degeneration | An obsolete terms for cloudy swelling. (05 Mar 2000) |
| amyloid degeneration | Infiltration of amyloid between cells and fibres of tissues and organs. Synonym: waxy degeneration. (05 Mar 2000) |
| angiolithic degeneration | Calcareous degeneration of the walls of the blood vessels. (05 Mar 2000) |
| ascending degeneration | Retrograde degeneration of an injured nerve fibre; i.e., toward the nerve cell of the fibre, degeneration cephalad to a spinal cord lesion. (05 Mar 2000) |
| atheromatous degeneration | Focal accumulation of lipid material (atheroma) in the intima and subintimal portion of arteries, eventually resulting in fibrous thickening or calcification. (05 Mar 2000) |
| axonal degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
| axon degeneration | A type of peripheral nerve fibre response to insult, wherein axon death and subsequent breakdown occurs, with secondary breakdown of the myelin sheath associated; caused by focal injury to peripheral nerve fibres; often referred to as wallerian degeneration. Synonym: axon degeneration. (05 Mar 2000) |
Synonyms : Early Onset Cerebellar Ataxia, Familial Spinocerebellar Degenerations, Hereditary Spinocerebellar Degenerations, Inherited Spinocerebellar Degenerations, Late Onset Cerebellar Ataxia, Marie's Cerebellar Ataxia, Spino Cerebellar Degenerations
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