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  • fluorescence activated cell sorter
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FACS Fellow of the American College of Surgeons; fluorescence-activated cell sorter
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FACS Fluorescence Activated Cell Sorter
FACS Fluorescent Activated Cell Sorter
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 4 ÆäÀÌÁö: 1
cell sorter <apparatus> A device used to separate different kinds of cells from a mixed, or heterogeneous, population.
(26 Mar 1998)
wool-sorter's disease A form of anthrax acquired by inhalation of dust containing Bacillus anthracis; there is an initial chill followed by pain in the back and legs, rapid respiration, dyspnea, cough, fever, rapid pulse, and extreme cardiovascular collapse.
Synonym: anthrax pneumonia, ragpicker's disease, ragsorter's disease, rag-sorter's disease, wool-sorter's pneumonia, woolsorter's disease, wool-sorter's disease.
(05 Mar 2000)
wool-sorter's pneumonia A form of anthrax acquired by inhalation of dust containing Bacillus anthracis; there is an initial chill followed by pain in the back and legs, rapid respiration, dyspnea, cough, fever, rapid pulse, and extreme cardiovascular collapse.
Synonym: anthrax pneumonia, ragpicker's disease, ragsorter's disease, rag-sorter's disease, wool-sorter's pneumonia, woolsorter's disease, wool-sorter's disease.
(05 Mar 2000)
fluorescence-activated cell sorter <technique> Flow cytometry is an emerging technique which holds great promise for the separation, classification and quantitation of blood cells and antibodies which affect blood cells.
Complex computerised instruments are used to pass a monocellular stream of cells, platelets or other microscopic particulate elements through a beam of laser light. The cells are categorised first by size and then computer analysed to sort the mixture of cellular elements into cell type by size.
Cells are labelled with fluorescent dye and then passed, in suspending medium, through a narrow dropping nozzle so that each cell is in a small droplet. A laser based detector system is used to excite fluorescence and droplets with positively fluorescent cells are given an electric charge. Charged and uncharged droplets are separated as they fall between charged plates and so collect in different tubes. The machine can be used either as an analytical tool, counting the number of labelled cells in a population or to separate the cells for subsequent growth of the selected population. Further sophistication can be built into the system by using a second laser system at right angles to the first to look at a second fluorescent label or to gauge cell size on the basis of light scatter. The great strength of the system is that it looks at large numbers of individual cells and makes possible the separation of populations with, for example: particular surface properties.
Tabulation of counted data in conjunction with size analysis enables determination of relative percentages of each specific cellular subset for which monoclonal antibody conjugates are utilised, even when the size of the cell is identical to other subset species.
Flow cytometry is a slightly imprecise but common term for the use of the Fluorescence-activated Cell Sorter (FACS).
(01 Dec 1998)
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sorter a clerk who sorts things (as letters at the post office) a machine for sorting things (such as punched cards or letters) into classes
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sorter This is a multi bin device that sorts and collates pages as you copy them. Sorters are available with staplers built in that staple pages as they are completed.
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sorter a machine for sorting things (such as punched cards or letters) into classes
sorter a clerk who sorts things (as letters at the post office)
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