| ¿µ¹® | mutation | ÇÑ±Û | µ¹¿¬º¯ÀÌ |
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| ¼³¸í | ¼¼Æ÷ÀÇ dna ÀÚüÀÇ º¯ÀÌ¿¡ ÀÇÇØ ÀϾ´Â ¼¼Æ÷º¯À̸¦ ¸»ÇÑ´Ù. ÀÌ·¯ÇÑ °æ¿ì µ¹¿¬º¯ÀÌ·Î ÀÏ¾î³ ¼¼Æ÷´Â ±× ÀÌÈÄ µþ¼¼Æ÷(daughter cell)¿¡¼µµ ±× º¯À̰¡ ¿©ÀüÈ÷ À¯ÁöµÇ¹Ç·Î Á¾(species)ÀÇ º¯È³ª, ȤÀº ¼¼Æ÷ÀÇ ¾Ç¼ºº¯È¯(malignant transformation)¿¡ °ü¿©ÇÑ´Ù. |
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| ¿µ¹® | ovarian cancer | ÇÑ±Û | ³¼Ò¾Ï |
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| ¼³¸í | ¿©¼ºÀÇ ³¼Ò¿¡ ¹ß»ýÇÏ´Â ¾Ï. ºÎÀΰúÁ¾¾çÀ¸·Î¼ 50¼¼ ÀÌ»ó ¿©¼º¾Ç¼ºÁ¾¾çÀÇ ¾à 18%¸¦ Â÷ÁöÇÑ´Ù. Á¾¾çÀº ´ë°³ º¹ºÎ ±í¼÷È÷ À§Ä¡ÇϹǷΠÁ¾¾çÀÌ ¸¹ÀÌ ÁøÇàµÈ »óÅ¿¡¼ ¹ß°ßµÇ´Â ¼ö°¡ ¸¹À¸¸ç, ¶ÇÇÑ Á¾¾çÀÇ Ãʱ⿡´Â Áõ»óÀÌ °ÅÀÇ ¾ø´Â °æ¿ì°¡ ¸¹¾Æ ´õ¿í Á¶±â¹ß°ßÀÌ ¾î·Æ´Ù. ¾ÆÁÖ ´Ù¾çÇÑ Á¾·ùÀÇ ¾ÏÀÌ ¹ß»ýÇϸç, ¿¹Èĵµ °¢±â ±× Á¾¾çÀÇ Á¾·ù¿¡ µû¶ó ´Ù¸£´Ù. ´ëÇ¥ÀûÀÎ ¾ÏÀ¸·Î À强³¶»ù¾ÏÁ¾(serous cystadenocarcinoma), Á¡¾×³¶»ù¾ÏÁ¾(mucinous cystadenocarcinoma), Á¾ÀÚ¼¼Æ÷Á¾(germinoma µîÀÌ ÀÖ´Ù. Ä¡·á´Â ¼ö¼úÀû Ä¡·á°¡ ¼±ÇàµÇ¾î¾ß ÇÏÁö¸¸, ¸¹ÀÌ ÁøÇàµÇ¾î ÀÌ¹Ì ´Ù¸¥ Á¶Á÷À¸·Î ÀüÀ̰¡ ÀÌ·ç¾îÁø »óÅ¿¡¼´Â ÈÇпä¹ýÀÌ ¼±ÅÃÀûÀ¸·Î »ç¿ëµÈ´Ù. |
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| ¿µ¹® | cancer | ÇÑ±Û | ¾Ï |
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| ¼³¸í | ³¡¾øÀÌ ºÐ¿À» ÇÏ¿© Ç÷¾×À̳ª ¸²ÇÁ°üÀ» ÅëÇÏ¿© ´Ù¸¥ Àå±â¿¡±îÁö ÀüÆÄµÉ ¼ö ÀÖ´Â ¼¼Æ÷ÀÇ µ¢¾î¸®. Áï ¾Ç¼º ½Å»ý¹°À» ¸»ÇÑ´Ù. ½Å»ý¹°Àº ¾Ç¼º°ú ¾ç¼ºÀÌ Àִµ¥, ¾Ç¼ºÀÏ °æ¿ì¿¡´Â ¼ºÀåÀÌ ¸Å¿ì ºü¸£°í Ç÷¾×À̳ª ¸²ÇÁ°üÀ» ÅëÇØ¼ ¸Ö¸® ´Ù¸¥ ¶³¾îÁø Àå±â·Î ¾Ï¼¼Æ÷ÀÇ ÀüÆÄ°¡ °¡´ÉÇÏ¿© ´Ù¸¥ Àå±â¿¡µµ ¾ÏÀ» ÀüÀÌÇϸç, ¾ç¼ºÀº õõÈ÷ ÀÚ¶ó°í ´Ù¸¥°÷À¸·Î ÀüÀ̰¡ »ý±âÁö ¾Ê´Â´Ù. ¾ÏÀº ¾ÏÁ¾°ú À°Á¾ÀÇ µÎ °¡Áö·Î ³ª´ ¼ö°¡ ÀÖ´Ù. ¾ÏÁ¾À̶õ »óÇǼ¼Æ÷ÀÇ °úµµÇÑ Áõ½Ä¿¡ ÀÇÇÑ ¾Ç¼º½Å»ý¹°À» À̸£´Â ¸»À̰í À°Á¾À̶õ ºñ»óÇǼº¼¼Æ÷ ƯÈ÷ Áß°£¿±¼¼Æ÷(¹ß»ý´ç½Ã¿¡ Áß°£¿±¿¡ ÇØ´çÇÏ´Â Á¶Á÷À¸·Î ¹ß»ýÈÄ¿¡ Á¶Á÷»çÀÌ¿¡ ºÐÆ÷ÇÏ¸é¼ Á¶Á÷À» ÁöÁöÇÏ´Â ¿ªÇÒÀ» ÇÏ´Â °áÇÕÁ¶Á÷, Ç÷°ü, ¸²ÇÁ°ü µîÀÌ µÈ´Ù)ÀÇ °úµµÇÑ Áõ½Ä¿¡ ÀÇÇÑ ¾Ç¼º ½Å»ý¹°À» À̸£´Â ¸»ÀÌ´Ù. |
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| ¿µ¹® | cancer surgery | ÇÑ±Û | ¾Ï ¼ö¼ú |
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| ¼³¸í | ¾ÏÀÇ 4´ë Ä¡·á¹ýÀº ¿Ü°úÀû ¼ö¼ú¿ä¹ý, ¹æ»ç¼± Ä¡·á¹ý, Ç×¾Ï ÈÇпä¹ý, ¸é¿ª¿ä¹ý µîÀ» ¸»Çϸç ÀÌÁß ¼ö¼ú¿ä¹ý°ú ¹æ»ç¼± ¿ä¹ýÀº ±¹¼ÒÀû ¿ä¹ýÀ¸·Î¼ ¾Ï¼¼Æ÷°¡ ¿ø¹ßÀå±â(óÀ½ ¾ÏÀÌ ¹ß»ýÇÑ Àå±â)³ª ±¹¼Ò ¸²ÇÁÀý±îÁö ±¹ÇѵǾî ÀÖ´Â Á¦ 1, 2±â ¾ÏÀÇ Ä¡·á¿¡ »ç¿ëµÈ´Ù. ÈÇпä¹ý°ú ¸é¿ª¿ä¹ýÀº Àü½Å¿ä¹ýÀ¸·Î¼ Á¦ 3, 4±â ¾Ï¿¡ ÁÖ·Î »ç¿ëµÇ¸ç, 1, 2±â ¾ÏÀÇ Ä¡·á ÈÄ ´«¿¡ º¸ÀÌÁö ¾Ê°Ô ³²¾Æ ÀÖÀ» ¼ö ÀÖ´Â ÀÜ·ù¾Ï¼¼Æ÷³ª ¹Ì¼¼ÀüÀÌ ¾Ï¼¼Æ÷ÀÇ ¿ÏÀüÆÄ±«, »ç¸êÀ» À§ÇØ »ç¿ëµÈ´Ù. ¹éÇ÷º´, ¸²ÇÁÁ¾°ú °°ÀÌ ÈÇпä¹ýÁ¦¿¡ Àß µè´Â Ç÷¾×¾Ï, ¸²ÇÁÁ¾°ú °íȯÁ¾°ú °°ÀÌ ¹æ»ç¼± Ä¡·á¿¡ Àß µè´Â ¾ÏÀ» Á¦¿ÜÇÑ ´ëºÎºÐÀÇ °íÇü¾Ï(solid tumor)ÀÎ À§Ã¢ÀÚ°ü¾Ï, °£¾Ï, ÀÌÀÚ¾Ï, À¯¹æ¾Ï, °©»ó»ù¾Ï, Æó¾Ï, Èæ»öÁ¾, ¿¬Á¶Á÷¾Ï, »ÀÀ°Á¾, ħ»ù¾Ï µîÀº ¸ðµÎ ¼ö¼ú¿ä¹ýÀ¸·Î Ä¡·áÇÏ¿©¾ß ÇÑ´Ù. ¾Ï¼ö¼úÀÇ ±âº»¿øÄ¢: ¾Ï¼ö¼úÀÇ 3°¡Áö ±âº»¿ä°ÇÀº ¾ÈÀü¼º, ±ÙÄ¡¼º, ±â´Éº¸Á¸¼ºÀÌ¸ç ¾Ï¼ö¼ú½Ã¿¡´Â ¾Ïº´Å͸¦ µÇµµ·Ï Á¶½ÉÇØ¼ Àû°Ô ¸¸Áö¸é¼ ¼ö¼úÇÏ°í ¾Ïº´Å͸¦ °ø±ÞÇÏ´Â µ¿Á¤¸Æ°ú ¸²ÇÁ°üÀ» ¸ÕÀú °áÂûÇÏ¿© ¾Ïº´ÅͰ¡ ÆÛÁö´Â °ÍÀ» ¹æÁöÇÑ´Ù. ¾Ï¼ö¼úÀÇ ¸ñÇ¥´Â ±ÙÄ¡Àû ÀýÁ¦¼ö¼ú(radical surgery)ÀÌ´Ù. ±×·¯³ª À̰ÍÀÌ ºÒ°¡´ÉÇÑ È¯ÀÚ¿¡¼´Â ÃâÇ÷, Æó»ö, õ°ø µîÀÇ ÇÕº´ÁõÀÌ ¹ß»ýÇßÀ»¶§ ±¸±Þ¸ñÀûÀ¸·Î ȤÀº Áö¼ÓÀû µ¿ÅëÀÌ ÀÖÀ»¶§ »ýȰ³»¿ëÀÇ ÁúÀû °³¼±À» À§ÇÏ¿© °í½ÄÀû ¼ö¼ú(palliative surgery)À» ÇÑ´Ù. ±×¸®°í ¾ÏÀÇ Á¤È®ÇÑ Áø´Ü°ú ÁøÇ൵ÀÇ °áÁ¤À» À§ÇÑ Áø´ÜÀû ¼ö¼ú(diagnostic surgery)ÀÌ ÀÖ´Ù. |
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| ¿µ¹® | breast cancer | ÇÑ±Û | À¯¹æ¾Ï |
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| ¼³¸í | À¯¹æÀº Áö¹æÁ¶Á÷°ú º»·¡ÀÇ ¸ñÀûÀÎ Á£À» »ý»êÇÏ´Â »ùÁ¶Á÷, ±×¸®°í ÀÌ »ùÁ¶Á÷¿¡¼ »ý»êÇÑ Á£À» ¹Û¿¡±îÁö ³»º¸³»´Â °üÁ¶Á÷, ±×¸®°í ÀÌ »ùÁ¶Á÷°ú °üÁ¶Á÷ÀÇ ÁÖÀ§¸¦ µÑ·¯½Î°í ÀÖÀ¸¸é¼ À̰͵éÀÇ ¸ð¾çÀ» À¯ÁöÇØÁÖ´Â °£Áú·Î ÀÌ·ç¾îÁø´Ù. À¯¹æ¾ÏÀ̶õ »ùÁ¶Á÷°ú °üÁ¶Á÷¿¡¼ ±â¿øÇÏ´Â Á¾¾çÀ» ¸»ÇÑ´Ù. À¯¹æ¾ÏÀ» ¹ß»ý½Ãų ¼ö ÀÖ´Â À§ÇèÀÎÀÚ´Â ¿©·¯ °¡Áö°¡ ¹àÇôÁ® ÀÖ´Ù. ±×Áß¿¡¼ ´ëÇ¥ÀûÀÎ °ÍÀº ´ÙÀ½°ú °°´Ù. 1.À¯ÀüÀû ¿äÀΣ°¡Á· Áß¿¡¼ À¯¹æ¾Ï¿¡ °É¸° »ç¶÷ÀÌ ÀÖÀ¸¸é À¯¹æ¾ÏÀÇ ¹ß»ýÈ®·üÀÌ ¾ÆÁÖ ³ô¾ÆÁø´Ù. 2.¿¡½ºÆ®·Î°Õ¿¡ Àå±âÀûÀ¸·Î ¸¹ÀÌ Æø·ÎµÇ´Â °æ¿ì£¿¡½ºÆ®·Î°ÕÀº ¿©¼ºÈ£¸£¸óÀ¸·Î ¿©¼º¿¡¼ Á¤»óÀûÀ¸·Î »ý¸®ÀÇ Áֱ⿡ µû¶ó Áõ°¨À» µÇÇ®ÀÌÇÑ´Ù. ÀÌ ¿¡½ºÆ®·Î°ÕÀº À¯¹æÀÇ Á¥»ùÁ¶Á÷°ú °üÁ¶Á÷ÀÇ Áõ½Ä°ú ¼ºÀå¿¡ °ü°èÇÑ´Ù. ±×¸®°í ÀÌ ¿¡½ºÆ®·Î°Õ¿¡ ¸¹ÀÌ Æø·ÎµÇ´Â »ç¶÷Àº À¯¹æ¾ÏÀÇ È®·üÀÌ ³ô´Ù. ¿ÜºÎ¿¡¼ ¿¡½ºÆ®·Î°ÕÀÇ Á¦Á¦¸¦ Ä¡·á¸ñÀûÀ¸·Î Åõ¿©ÇÒ °æ¿ì¿¡ À¯¹æ¾ÏÀÇ ¹ß»ýÈ®·üÀº Á¤»óÀο¡¼ º¸´Ù ÇöÀúÇÏ°Ô ³ô¾ÆÁø´Ù. ±×¸®°í ¾ÆÀ̸¦ ³ºÁö ¾Ê°í Æò»ýÀ» »ç´Â ¿©ÀÚÀÇ °æ¿ì¿¡ ÀÓ½ÅÀ» ÇÏ°í ¾ÆÀ̸¦ ³ºÀº ¿©ÀÚ¿¡ ºñÇØ¼ ¿¡½ºÆ®·Î°Õ¿¡ ¸¹ÀÌ Æø·Î°¡ µÇ¹Ç·Î(ÀӽŽÿ¡´Â ºñÀӽŽú¸´Ù ¿¡½ºÆ®·Î°Õ¿¡ Àû°Ô Æø·Î°¡ µÈ´Ù)À¯¹æ¾ÏÀÇ È®·üÀÌ ³ô´Ù. 3.ȯ°æÀû ¿äÀΣÁö¹æÁú ¼·ÃëÀÇ Áõ°¡, ¼úÀÇ ¼·Ãë µîÀº À¯¹æ¾ÏÀÇ È®·üÀ» ³ôÀδÙ. À¯¹æ¾ÏÀÇ Áõ»óÀ¸·Î °¡Àå ¸¹Àº °ÍÀº ¾ÆÇÁÁö ¾ÊÀº À¯¹æÀÇ µ¢¾î¸®ÀÌ´Ù. ±×¸®°í À¯µÎ¿¡¼ ºÐºñ¹°ÀÌ ³ª¿À°Å³ª, À¯¹æÀÇ ÇǺκ¯È µîÀÌ À¯¹æ¾ÏÀÇ ÈçÇÑ Áõ»óÀÌ´Ù. Ä¡·á´Â À¯¹æÀÇ ÀýÁ¦¼úÀÌ °¡Àå È¿°úÀûÀÎ Ä¡·á¹ýÀ¸·Î µÇ¾îÀÖ´Ù. ±×¸®°í À̰Ϳ¡ ´õÇÏ¿© ¹æ»ç¼± Ä¡·á³ª Ç×¾ÏÁ¦¿ä¹ýµµ È¿°ú°¡ ÀÖ´Â °ÍÀ¸·Î µÇ¾îÀÖ´Ù. ¶Ç ¿¡½ºÆ®·Î°ÕÀÇ °úÀ×°ú °ü°è°¡ ÀÖ´Â Á¾¾çÀÏ °æ¿ì¿¡´Â ¿¡½ºÆ®·Î°ÕÀÇ È¿°ú¸¦ Â÷´ÜÇÏ´Â ¾à¹°µµ È¿°ú°¡ ÀÖ´Ù. |
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| SDT | sensory detection theory; right sacrotransverse [fetal position] [Lat. sacrodextra transversa]; sign... |
|---|---|
| AFP | Alpha(¥á) Feto-Protein [HP 1826, 1858, 1859, 2265] ; Oncofetal Antigens &nbs... |
| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| SMART | Somatic Mutation And Recombination Test |
|---|---|
| SCC | Somatic Cell Count |
| DFT | Density Functional Theory |
| IRT | Item Response Theory |
| SDT | Signal Detection Theory |
| somatic mutation theory of cancer | That cancer is caused by a mutation or mutations in the body cells (as opposed to germ cells), especially nonlethal mutations associated with increased proliferation of the mutant cells. (05 Mar 2000) |
|---|
| somatic mutation | Mutation that occurs in the somatic tissues of an organism and that will not, therefore, be heritable, since it is not present in the germ line. Some neoplasia is due to somatic mutation, a more conspicuous example is the reversion of some branches of variegated shrubs to the wild type (completely green) phenotype. Somatic mutation is probably also important in generating diversity in V gene regions of immunoglobulins. (18 Nov 1997) |
|---|---|
| general somatic afferent column | In the embryo, a column of gray matter in the hindbrain and spinal cord, represented in the adult by the sensory nuclei of the trigeminal nerve and relay cells in the dorsal horn. (05 Mar 2000) |
| general somatic efferent column | A column of gray matter in the embryo, represented in the adult by the nuclei of the oculomotor, trochlear, abducens, and hypoglossal nerves and by motor neurons of the ventral horn of the spinal cord. (05 Mar 2000) |
| psychiatric somatic therapies | The biologic treatment of mental disorders (e.g., electroconvulsive therapy), in contrast with psychotherapy. (stone, american psychiatric glossary, 1988, p159) (12 Dec 1998) |
| somatic | 1. Pertaining to or characteristic of the soma or body. 2. Pertaining to the body wall in contrast to the viscera. Origin: Gr. Somatikos (18 Nov 1997) |
| somatic agglutinin | An agglutinin that is formed as the result of stimulation by, and that reacts with, the relatively thermostable antigen(s) in the cell bodies of microorganisms. Synonym: somatic agglutinin. See ABO blood group. (05 Mar 2000) |
| somatic antigen | An antigen located in the cell wall of a bacterium in contrast to one in the flagella (flagellar antigen) or in a capsule (capsular antigen). (05 Mar 2000) |
| somatic arteries | Artery's that arise in the embryo from the dorsal aorta and supply the body wall; they persist almost unchanged as the posterior intercostal, subcostal, and lumbar artery's. (05 Mar 2000) |
| somatic cell | Usually any cell of a multicellular organism that will not contribute to the production of gametes, i.e. most cells of which an organism is made: not a germ cell. Notice, however, the alternative use in somatic mesoderm. (18 Nov 1997) |
| somatic cell gene therapy | The repair or replacement of a defective gene within somatic tissue. (09 Oct 1997) |
| somatic cell genetics | Method for identifying the chromosomal location of a particular gene without sexual crossing. Unstable heterokaryons are made between the cell of interest and another cell with identifiably different characteristics (or without the gene in question) and a series of clones isolated. By correlating retention of gene expression with the remaining chromosomes, it is possible to deduce which chromosome must carry the gene. Human mouse heterokaryons have been extensively used in this sort of work. (18 Nov 1997) |
| somatic cell hybridization | Production of a heterokaryon. (05 Mar 2000) |
| somatic cells | Cells of an animal or plant other than the reproductive cells. (14 Nov 1997) |
| somatic crossing-over | Crossing-over that occurs during the mitosis of somatic cells, in contrast to that which occurs in meiosis. (05 Mar 2000) |
| somatic death | Death of the entire body, as distinguished from local death. (05 Mar 2000) |
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