| 영문 | signal transduction | 한글 | 신호전달 |
|---|---|---|---|
| 설명 | 세포에 있어 수용체의 신호수용에서 기능발현에 이르기까지의 정보전달. 지용성의 스테로이드호르몬이나 비타민 등을 제외하고 수용성호르몬, 신경화학물질이나 세포증식인자 등은 세포막상에 특이적인 수용체를 갖고 정보를 세포내로 전하여 다양한 세포반응을 일으킨다. |
||
| 영문 | irritation, stimulus | 한글 | 자극 |
|---|---|---|---|
| 설명 | 생물에 작용하여 특정의 반응을 일으키는 요인. 보통 외계의 조건 변화에 따라 생물체에 특유한 활동이 왕성해지는 것을 생물체가 흥분했다고 하며, 흥분을 일으키는 원인이 된 외계의 조건 변화를 자극이라고 한다. 예를 들면, 바늘 끝으로 손등을 찌르면 신경섬유에 자극을 주게 되어, 이 신경섬유에 충격이라고 하는 어떤 변화가 생긴다. 이 충격이 전도되어 간다. 이 상태를 신경섬유가 흥분했다고 한다. 외적조건의 변화가 이것에 대응하는 감각기가 수용하여 자극이 되는데, 자극에 대한 반응에 반사적으로 일어나는 눈깜박이와 같은 국부적인 것이 있고, 기온의 변화에 대해서와 같이 전신적인 것도 있다. 세포자극으로서 작용하는 외계의 조건 변화는 그 에너지의 종류에 따라 기계적 자극-화학적 자극-온열적 자극-삼투압 자극-전기적 자극 등이 있다. 그 중 전기적 자극은 생체 속에서 자연히 일어나는 자극과 그로 인해 일어나는 흥분이 모두 전기적 과정이므로 자연히 일어나는 자극과 같거나, 그것에 가까운 것이다. 어떤 종류의 조건 변화는 도리어 흥분을 일으키기 어렵게 하는 것도 있다. |
||
| RS | radioscaphoid; random sample; rating schedule; Raynaud syndrome; recipient's serum; rectal sinus; re... |
|---|---|
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| DSP | decreased sensory perception; delayed sleep phase; desmoplakin; dibasic sodium phosphate; digital si... |
| EPI/STAR | echo planar imaging with signal targeting and alternating radiofrequency |
| ERK | extracellular signal-regulated kinase |
| US | 1-unconditioned stimulus |
|---|---|
| CS | Conditioned Stimulus |
| DS | Discriminative Stimulus |
| ISI | Inter-stimulus interval |
| PST | Per-stimulus-time |
| COOH-terminal signal transamidase | <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor Registry number: EC 2.3.2.- Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase (26 Jun 1999) |
|---|---|
| signal | 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton) 2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service. Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous. Origin: From signal, n., cf. F. Signale. Source: Websters Dictionary (01 Mar 1998) |
| signal detection (psychology) | A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment. (12 Dec 1998) |
| signal node | A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion. Synonym: jugular gland, Virchow's node. (05 Mar 2000) |
| signal peptidase | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptidase complex | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
| signal peptides | Additional polypeptide sequence of 25 to 30 residues at the amino-terminal or carboxy-terminal end of proteins. The signal sequence signals the cellular fate or destination of a newly synthesised protein directing it to its ultimate destination in the cell. These leaders are recognised by the signal recognition particle and bound by specific receptor sites on the outer surface of the endoplasmic reticulum. They are then transported into the cisterna of the endoplasmic reticulum and from there directed to their ultimate destination in the cell. In prokaryotes, the signal peptides attach to the plasma membrane. These signal sequences are ultimately removed by specific peptidases. (12 Dec 1998) |
| signal processing, computer-assisted | Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity. (12 Dec 1998) |
| signal recognition particle | A complex between a 7S RNA and six proteins. SRP binds to the nascent polypeptide chain of eukaryotic proteins with a signal sequence and halts further translation until the ribosome becomes associated with the rough endoplasmic reticulum. One of the SRP proteins (srp54) binds GTP and in association with 7SRNA and srp19 has GTPase activity. (18 Nov 1997) |
| signal recognition particle receptor | Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. (18 Nov 1997) |
| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| signal sequence | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal-to-noise ratio | <microscopy> Also sometimes used as an abbreviation for serial number, can be somewhat confusing in the case of electronic equipment. (05 Aug 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|