| ¿µ¹® | signal transduction | ÇÑ±Û | ½ÅÈ£Àü´Þ |
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| ECG | Electro-Cardio-Graphy(-Gram); ½ÉÀüµµ = EKG 1. Conducting System Structu... |
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| AER | abduction/external rotation; acoustic evoked response; acute exertional rhabdomyolysis; agranular en... |
| SR | sarcoplasmic reticulum; saturation recovery; scanning radiometer; screen; secretion rate; sedimentat... |
| CF | calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ... |
| F0, | F1 coupling factor |
| E-C coupling | Excitation-contraction coupling |
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| CF1 | Coupling Factor 1 |
| ECC | Excitation-contraction coupling |
| CI | coupling interval |
| ERK | 1-extracellular signal-regulated kinase |
| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
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| viscous mechanical coupling | <cell biology> Method by which adjacent cilia are synchronised in a field. Coupling is through the transmission of mechanical forces, rather than of a synchronising signal. (18 Nov 1997) |
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| chemiosmotic coupling | The linking of ATP synthesis to electrontransfer by way of an electrochemical hydrogen cation gradient across amembrane. (09 Oct 1997) |
| metabolic coupling | <cell biology, molecular biology> Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids. Transfer is via channels constituted by the connexons of gap junctions and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radio labelled purines were transferred from wild type cells to mutants unable to utilise exogenous purines. (27 Jun 1999) |
| constant coupling | Where several premature beats are seen, the interval between each of them and the preceding normal beat is constant. Synonym: constant coupling. Variable coupling, where several extrasystoles are seen, the interval between each of them and the preceding sinus beat varies. (05 Mar 2000) |
| COOH-terminal signal transamidase | <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor Registry number: EC 2.3.2.- Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase (26 Jun 1999) |
| coupling | <biochemistry> The linking of two independent processes by a common intermediate, for example the coupling of electron transport to oxidative phosphorylation or the ATP ADP conversion to transport processes. (18 Nov 1997) |
| coupling defect | See: familial goiter. (05 Mar 2000) |
| coupling factor | Protein responsible for coupling transmembrane potentials to ATP synthesis in chloroplasts and mitochondria. Include ATP synthesising enzymes (F1 in mitochondrion), that can also act as ATP ases. (18 Nov 1997) |
| coupling factors | Proteins that restore phosphorylating ability to mitochondria that have lost it, i.e., have become "uncoupled" so that oxidation and electron transport no longer produces ATP. Usually termed coupling factor F1, F2, etc. Synonym: C factors. (05 Mar 2000) |
| coupling interval | The interval, usually expressed in hundredths of a second, between a normal sinus beat and the ensuing premature beat. (05 Mar 2000) |
| coupling phase | The physical relationship of two syntenic genes. If they are on the same chromosome, they are said to be "in coupling" or "in the cis phase"; if on opposite members of a chromosome pair, "in repulsion" or "in the trans phase." (05 Mar 2000) |
| signal | 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton) 2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service. Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous. Origin: From signal, n., cf. F. Signale. Source: Websters Dictionary (01 Mar 1998) |
| signal detection (psychology) | A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment. (12 Dec 1998) |
| signal node | A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion. Synonym: jugular gland, Virchow's node. (05 Mar 2000) |
| signal peptidase | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
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