| ¿µ¹® | bone marrow | ÇÑ±Û | °ñ¼ö |
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| ¿µ¹® | bone marrow biopsy | ÇÑ±Û | °ñ¼ö»ý°Ë |
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| ¼³¸í | °ñ¼ö¸¦ Áø´ÜÀ̳ª º´¿¡ ÀÇÇÑ º¯È¸¦ ¾Ë±âÀ§Çؼ äÃëÇÏ´Â °Í. |
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| ¿µ¹® | bone marrow transplantation | ÇÑ±Û | °ñ¼öÀÌ½Ä |
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| ¿µ¹® | zygomatic bone | ÇÑ±Û | ±¤´ë»À |
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| ¿µ¹® | bone | ÇÑ±Û | »À, °ñ |
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| ¼³¸í | ±¸¼º£»À(»ÀÁ¶Á÷). ÀÌ Á¶Á÷Àº ±²ÀåÈ÷ ´Ü´ÜÇÑ Á¶Á÷À¸·Î »À¸ð¼¼Æ÷¿¡ ÀÇÇØ¼ »ý¼ºµÈ´Ù. »À¸ð¼¼Æ÷°¡ »ý¼ºÇÑ ÀÌ Á¶Á÷Àº »À¼¼Æ÷¶ó´Â ¼¼Æ÷¸¦ µ¿½É¿ø¸ð¾çÀ¸·Î ½×°í ÀÖ´Ù. žƽñ⿡´Â ¸ðµç »À°¡ ¿¬°ñÁ¶Á÷À¸·Î µÇ¾îÀÖ´Ù. ÀÌ·± ¿¬°ñÁ¶Á÷ÀÌ ¹ß»ýÇÏ¸é¼ Á¡Á¡ Ä®½·¿°ÀÇ Ä§Âø¿¡ ÀÇÇØ¼ »ÀÁ¶Á÷ÀÌ »ý±ä´Ù. ±×¸®°í ¾î¸°ÀÌÀÇ °æ¿ì¿¡´Â »À³¡ÆÇ(epiphyseal plate)¶ó´Â °÷ÀÌ Àִµ¥ À̰÷µµ ¿ª½Ã ¿¬°ñÁ¶Á÷À¸·Î µÇ¾îÀÖ¾î¼ Áö¼ÓÀûÀ¸·Î ¿¬°ñÁ¶Á÷À» ¸¸µé°í Ä®½·¿°ÀÇ Ä§ÂøÀÌ »ý°Ü¼ »ÀÀÇ ¼ºÀåÀÌ µÈ´Ù. ¾çÂÊ¿¡ ³Ð¾îÁø °÷À» »À³¡(epiphysis)¶ó°í ÇÏ°í ¸·´ë¸ð¾çÀÇ Áß°£ºÎºÐÀ» »À¸öÅë(diaphysis)¶ó°í Çϰí ÀÌ ¾çÂÊÀÇ ÀÌÇàºÎÀ§¸¦ »À¸öÅ볡(metaphysis)¶ó°í ÇÑ´Ù. »À³¡°ú »À¸öÅ볡ÀÇ °æ°èºÎÀ§¿¡ ¾î¸°ÀÌ¿¡°Ô¼± »À³¡ÆÇ(epiphyseal plate)¶ó´Â °ÍÀÌ Á¸ÀçÇϴµ¥, À̰÷Àº ¿¬°ñÁ¶Á÷À¸·Î µÇ¾îÀÖÀ¸¸ç »ÀÀÇ ±æÀ̼ºÀå¿¡ Áß¿äÇÑ ¿ªÇÒÀ» ÇÏ´Â °ÍÀÌ´Ù. ¾î¸¥ÀÌ µÇ¸é À̰÷ÀÇ ¿¬°ñÁ¶Á÷Àº ¸ðµÎ °ñÁ¶Á÷À¸·Î º¯ÈµÇ¾î ÁÙ¸ð¾çÀÇ ÈçÀûÀÌ ³²´Âµ¥, À̰ÍÀ» »À³¡¼±À̶ó°í ÇÑ´Ù. ±ä»À¸¦ Àý´ÜÇØ º¸¸é °ÑÀ¸·Î´Â ¸Å¿ì ´Ü´ÜÇϰí Á¶Á÷ÀÌ Ä¡¹ÐÇϰí, ±× ¾ÈÂÊ¿¡´Â °Ñ¿¡ ºñÇØ¼ ¹«¸£°í, Á¶Á÷ÀÌ ¼º±ä °÷ÀÌ ÀÖ´Â °É ¾Ë ¼ö°¡ ÀÖ´Ù. °ÑÀÇ ´Ü´ÜÇÑ °÷À» Ä¡¹Ð»À(compact bone) ȤÀº °ÑÁú»À(cortical bone)À̶ó°í ÇÑ´Ù. ¿©±â¿¡´Â »ÀÁ¶Á÷ÀÌ µ¿½É¿ø ¸ð¾çÀ» ÀÌ·ç°í Ä¡¹ÐÇÏ°Ô ¹è¿µÇ¾î ÀÖ°í ±× µ¿½É¿ø ³»ºÎ¿¡´Â »À¼¼Æ÷°¡ À§Ä¡Çϰí ÀÖ´Ù. ±×¸®°í µ¿½É¿øÀÇ Áß°£¿¡´Â °üÀÌ ÀÖ¾î¼ À̰÷À» ÅëÇØ¼ Ç÷¾×°ú ¿µ¾çºÐÀÌ °ø±ÞµÇ´Âµ¥ À̰üÀ» Á߽ɰü(ÇϹö½º°ü)À̶ó°í ÇÑ´Ù. ±×¸®°í ³»ºÎ¿¡ À§Ä¡ÇÑ ¼º±ä °÷À» °¹¼Ø»À(Sponge Bone)À̶ó°í ÇÑ´Ù. ¿ª½Ã »ÀÁ¶Á÷À¸·Î ÀÌ·ç¾îÁø °÷ÀÌÁö¸¸ ±× ¹è¿ÀÌ Ä¡¹Ð»À¿¡ ºñÇØ¼ ¼º±â°í ¿ÜºÎÀÇ Èû¿¡ ´ëÇÑ ÀúÇ×µµ ¾àÇÑ Á¶Á÷ÀÌ´Ù. ÀÌ Á¶Á÷ÀÇ ³»ºÎ¿¡´Â Ç÷¾×ÀÇ ¼¼Æ÷¸¦ »ý¼ºÇÏ´Â °ñ¼ö¶ó´Â °ÍÀÌ Á¸ÀçÇÑ´Ù. ªÀº »À(short bone)£¼Õ¸ñÀ̳ª ¹ß¸ñ¿¡¼ º¼ ¼ö Àִ ª°í ¸ð¾çÀÌ ºÒ±ÔÄ¢ÇÑ »À. ³³ÀÛ»À(flat bone)£¸Ó¸®³ª °ñ¹ÝÀÇ »À¿Í °°ÀÌ ³³ÀÛÇÑ ¸ð¾çÀÇ »À. Á¾ÀÚ»À(sesamoid bone)£ÀÛ°í ±¸ÇüÀÎ »À. °üÀýÁÖÀ§¿¡ Á¸ÀçÇÑ´Ù. °³°³Àο¡ µû¶ó¼ Á¸ÀçÇϱ⵵ ÇÏ°í ±×·¸Áö ¾Ê±âµµ ÇÑ´Ù. |
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| BMC | blood mononuclear cell; bone marrow cell; bone mineral content |
|---|---|
| SC | conditioned stimulus; sacrococcygeal; Sanitary Corps; scalenus [muscle]; scapula; Schwann cell; scia... |
| SCA | self-care agency; severe congenital anomaly; sickle-cell anemia; single-camera autostereoscopic [ima... |
| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
| BC | Bachelor of Surgery [Lat. Baccal-aureus Chirurgiae]; back care; bactericidal concentration; basal ce... |
| SCA | Sickle cell anaemia |
|---|---|
| SCD | Sickle Cell Disease |
| SCT | Sickle cell trait |
| PSR | Proliferative sickle retinopathy |
| BPTB | Bone-patellar tendon-bone |
| sickle cell anaemia: bone manifestations | <radiology> 8-13% of blacks carry sickling factor, symptoms: chronic ulcers, pain crises, many infections, priapism X-ray findings: deossification due to marrow hyperplasia, decreased bone density in skull with widened diploe, H-shaped vertebrae or fish vertebrae, rib notching, thrombosis and infarction, avascular necrosis, especially femoral head, periosteal treatmentn (bone within bone), secondary osteomyelitis, Staph. Aureus greater than Salmonella, dactylitis = hand foot syndrome, growth effects, bone shortening secondary to diminished blood supply, death less than 40y (12 Dec 1998) |
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| anaemia, sickle cell | A disease characterised by chronic haemolytic anaemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for haemoglobin s. (12 Dec 1998) |
|---|---|
| sickle cell anaemia | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| amyloidosis: bone manifestations | <radiology> Joint pain without radiographic findings, osteoporosis, especially in axial skeleton, lytic lesions that destroy cortex and invade soft tissue, wrist, scaphoid and lunate lesions that may extend into the carpal tunnel, inducing the classic complaints of carpal tunnel syndrome amyloid arthropathy Differential diagnosis: pigmented villonodular synovitis, synovial chondromatosis, rheumatoid arthritis, TB (12 Dec 1998) |
| sickle cell | <haematology, pathology> An erythrocyte that changes from the normal discoid shape to a sickled shape when the oxygen tension is low. The pesence of these cells indicates that the patient is homozygotes for the allele that codes for haemoglobin S and that the patient has sickle cell anaemia. (18 Nov 1997) |
| sickle cell C disease | A disease resulting from abnormal sickle-shaped erythrocytes (containing haemoglobin C and S) which appear in response to a lowering of the partial pressure of oxygen; characterised by anaemia, crises due to haemolysis or vascular occlusion, chronic leg ulcers and bone deformities, and infarcts of bone or of the spleen. (05 Mar 2000) |
| sickle cell crisis | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| sickle cell dactylitis | <syndrome> Recurrent painful swelling of the hands and feet occurring in infants and young children with sickle cell anaemia. Synonym: sickle cell dactylitis. (05 Mar 2000) |
| sickle cell disease | <haematology> Disease common in races of people from areas in which malaria is endemic. The cause is a point mutation in the allele that codes for the beta chain of haemoglobin with a substitution of (valine for glutamic acid at position 6. The defective haemoglobin (HbS) crystallizes readily at low oxygen tension. In consequence, erythrocytes from homozygotes change from the normal discoid shape to a sickled shape when the oxygen tension is low and these sickled cells become trapped in capillaries or damaged in transit, leading to severe anaemia. In heterozygotes, the disadvantages of the abnormal haemoglobin are apparently outweighed by increased resistance to Plasmodium falciparum malaria, probably because parasitised cells tend to sickle and are then removed from circulation. Symptoms include joint pain, acute abdominal pain, and ulcerations of the lower extremities. Origin: Gr. Haima = blood (18 Nov 1997) |
| sickle cell haemoglobin | <haematology> Haemoglobin S is an abnormal version of the protein haemoglobin. The sixth amino acid of the normal beta chain, glutamic acid, is replaced by valine with gluconic acid. This mutation causes the red blood cell to take on a sickle shape, and is the cause of the sickle cell trait condition (when the individual is heterozygous for this mutant haemoglobin) and the disease of sickle cell anaemia (when the individual is homozygous for this mutant haemoglobin). (09 Oct 1997) |
| sickle cell prep | <haematology, investigation> A test which looks at red blood cells under the microscope to detect sickle cells after an agent which lowers the oxygen content of the sample is added. A positive test is result is determined by the presence of sickle cells. Abnormal results indicate sickle cell anaemia or sickle cell trait. (27 Sep 1997) |
| sickle cell retinopathy | A condition marked by dilation and tortuosity of retinal veins, and by microaneurysms and retinal haemorrhages; advanced stages may show neovascularization, vitreous haemorrhage, or retinal detachment. (05 Mar 2000) |
| sickle cell test | <investigation> A test which looks at red blood cells under the microscope to detect sickle cells after an agent which lowers the oxygen content of the sample is added. A positive test is result is determined by the presence of sickle cells. Abnormal results indicate sickle cell anaemia or sickle cell trait. (27 Sep 1997) |
| sickle cell-thalassaemia disease | Anaemia, clinically resembling sickle cell anaemia, in which individuals are compound heterozygous for the sickle cell gene and a thalassaemia gene; about 60 to 80% of haemoglobin is Hb S, up to 20% Hb F, and the remainder Hb anaemia. Synonym: sickle cell-thalassaemia disease. (05 Mar 2000) |
| sickle cell trait | <haematology> This condition occurs in people who have one of two possible genes (i.e., they are heterozygous forthe allele) that code for the defective haemoglobin responsible for sickle cell anaemia. The coditionis diagnosed by exposing an individual's red blood cells to a low oxygen environment, if the trait is present, the cells will turn to a sickle shape. People with this trait may suffer milder symptoms of sickle cell anaemia, or may have no symptoms. Some scientists believe the trait actually provides an evolutionary advantage in tropical environments because the slightly altered shape of the blood cells causes a person to be more resistant to malaria. (09 Oct 1997) |
| amyloidosis: gastrointestinal manifestations | <radiology> Oesophagus, loss of peristalsis, megaesophagus, stomach, small and rigid (simulate linitis plastica), effaced rugal pattern, diminished/absent peristalsis, may be localised to antrum, amyloidoma: well defined submucosal mass, small bowel, diffuse form (more common), diffuse, uniform thickening of valvulae conniventes, broadened flat undulated mucosal folds (mucosal atrophy), jejunalization of ileum, impaired motility, small bowel dilatation, localised form: multiple small deposits; associated with pseudoobstruction, colon, psudopolyps (12 Dec 1998) |
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