| ¿µ¹® | iodine uptake | ÇÑ±Û | ¿ä¿Àµå ¼·Ãë |
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| MAOI | MonoAmine Oxidase Inhibitors |
|---|---|
| 5-HT | 5-Hydroxy-Tryptamine = Serotonin |
| GSCN | giant serotonin-containing neuron |
| GSN | gelsonin; giant serotonin-containing neuron |
| 5-HT | 5-hydroxytryptamine [serotonin] |
| SSRI | Specific serotonin re-uptake inhibitors |
|---|---|
| Uptake-1 | uptake |
| AChE-I | acetylcholine esterase inhibitors |
| ChEI | Cholinesterase inhibitors |
| IAPs | Inhibitors of apoptosis |
thromboxane
| serotonin uptake inhibitors | Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behaviour, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the adrenergic uptake inhibitors also inhibit serotonin uptake; they are not included here. (12 Dec 1998) |
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| adrenergic uptake inhibitors | Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (antidepressive agents, tricyclic) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (12 Dec 1998) |
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| neurotransmitter uptake inhibitors | Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. (12 Dec 1998) |
| dopamine uptake inhibitors | Drugs that block the transport of dopamine into axon terminals or into storage vesicles within terminals. most of the adrenergic uptake inhibitors also inhibit dopamine uptake. (12 Dec 1998) |
| receptors, serotonin | Cell-surface proteins that bind serotonin and trigger intracellular changes which influence the behaviour of cells. Several types of serotonin receptors have been recognised which differ in their pharmacology, molecular biology, and mode of action. (12 Dec 1998) |
| selective serotonin reuptake inhibitor | <pharmacology> This is a class of drug that are used as antidepressants. Functionally, they increase the levels of serotonin in the body. These drugs can be dangerous if they are mixed with other drugs such as other antidepressants, illicit drugs (LSD, cocaine, methamphetamine), some antihistamines (Seldane, Histmanal), some antibiotics, and calcium channel blockers. Side effects include lethargy, confusion, flushing, sweating and muscle spasms. Overdose can cause damage to red blood cells, breathing problems and kidney damage. Examples include: Prozac, Zoloft and Paxil. Acronym: SSRI (12 Jan 1998) |
| serotonin | <biochemistry, hormone> A neurotransmitter and hormone (176 kD), found in vertebrates, invertebrates and plants. It is synthesised from the amino acid tryptophan by enterochromaffin cells in the gut and bronchi. It is metabolised to 5-HIAA in the liver and then excreted in the urine. Serotonin is measured on a venipuncture specimen in cases of suspected carcinoid syndrome (where it will be elevated). The normal range is 101 to 283 ng/ml. Acronym: 5-HT (13 Nov 1997) |
| serotonin agents | Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons. (12 Dec 1998) |
| serotonin agonists | Agents that have an affinity for serotonin receptors and are able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. These compounds are used as antidepressants, anxiolytics, and in the treatment of migraine. (12 Dec 1998) |
| serotonin antagonists | Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonin agonists. (12 Dec 1998) |
| serotonin-binding protein kinase | <enzyme> An aspect of protein kinases EC 2.7.1.37 Registry number: EC 2.7.1.- Synonym: sbp kinase (26 Jun 1999) |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
| gallium uptake with normal chest film | <radiology> Pulmonary drug toxicity, tumour infiltration, sarcoidosis, pneumocystis carinii see: lung: gallium imaging (12 Dec 1998) |
| radioactive iodide uptake test | A test of thyroid function in which 131I-iodide is given orally; after 24 hours, the amount present in the thyroid gland is measured and compared with normal values. Synonym: radioactive iodide uptake test, RAI test. (05 Mar 2000) |
| iodine uptake test | A test of thyroid function in which 131I-iodide is given orally; after 24 hours, the amount present in the thyroid gland is measured and compared with normal values. Synonym: radioactive iodide uptake test, RAI test. (05 Mar 2000) |
| T3 uptake test | A test of thyroid function in which triiodothyronine (T3) is added to a patient's serum in vitro to measure the relative affinities of serum proteins and of an added competitive substance for T3; higher T3 uptakes are associated with hyperthyroidism. Synonym: T3 uptake test. (05 Mar 2000) |
Synonyms : Inhibitors, 5-HT Uptake, Inhibitors, 5-Hydroxytryptamine Uptake, Inhibitors, Serotonin Reuptake, Inhibitors, Serotonin Uptake, Reuptake Inhibitors, Serotonin, Uptake Inhibitors, 5-HT, Uptake Inhibitors, 5-Hydroxytryptamine, Uptake Inhibitors, Serotonin
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