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5-HT 5-Hydroxy-Tryptamine
  = Serotonin
GSCN giant serotonin-containing neuron
GSN gelsonin; giant serotonin-containing neuron
5-HT 5-hydroxytryptamine [serotonin]
I5HT intraplatelet serotonin
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[(3)H]-5-HT 3)H]-serotonin
5-HT 3)H]serotonin
5-HT 5-hydroxytryptophan , a serotonin
5HT Histamine , serotonin
5-HT Hypothalamic serotonin
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  • thrombotonin µ¿ÀǾî=serotonin.

    thromboxane

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serotonin <biochemistry, hormone> A neurotransmitter and hormone (176 kD), found in vertebrates, invertebrates and plants. It is synthesised from the amino acid tryptophan by enterochromaffin cells in the gut and bronchi. It is metabolised to 5-HIAA in the liver and then excreted in the urine.
Serotonin is measured on a venipuncture specimen in cases of suspected carcinoid syndrome (where it will be elevated). The normal range is 101 to 283 ng/ml.
Acronym: 5-HT
(13 Nov 1997)
serotonin agents Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.
(12 Dec 1998)
serotonin agonists Agents that have an affinity for serotonin receptors and are able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. These compounds are used as antidepressants, anxiolytics, and in the treatment of migraine.
(12 Dec 1998)
serotonin antagonists Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonin agonists.
(12 Dec 1998)
serotonin uptake inhibitors Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behaviour, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the adrenergic uptake inhibitors also inhibit serotonin uptake; they are not included here.
(12 Dec 1998)
serotonin-binding protein kinase <enzyme> An aspect of protein kinases EC 2.7.1.37
Registry number: EC 2.7.1.-
Synonym: sbp kinase
(26 Jun 1999)
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receptors, serotonin Cell-surface proteins that bind serotonin and trigger intracellular changes which influence the behaviour of cells. Several types of serotonin receptors have been recognised which differ in their pharmacology, molecular biology, and mode of action.
(12 Dec 1998)
selective serotonin reuptake inhibitor <pharmacology> This is a class of drug that are used as antidepressants.
Functionally, they increase the levels of serotonin in the body. These drugs can be dangerous if they are mixed with other drugs such as other antidepressants, illicit drugs (LSD, cocaine, methamphetamine), some antihistamines (Seldane, Histmanal), some antibiotics, and calcium channel blockers.
Side effects include lethargy, confusion, flushing, sweating and muscle spasms. Overdose can cause damage to red blood cells, breathing problems and kidney damage.
Examples include: Prozac, Zoloft and Paxil.
Acronym: SSRI
(12 Jan 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Serotonin - »õâ A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
    Synonyms : 3-(2-Aminoethyl)-1H-indol-5-ol, Enteramine, Hippophaine, Hydroxytryptamine, 5 Hydroxytryptamine
  • Serotonin Agents - »õâ Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.
    Synonyms : Serotonergic Agents, Serotonergic Drugs, Serotonin Drugs, Agents, Serotonergic, Agents, Serotonin, Drugs, Serotonergic, Drugs, Serotonin
  • Serotonin Agonists - »õâ Agents that have an affinity for serotonin receptors and are able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. These compounds are used as antidepressants, anxiolytics, and in the treatment of MIGRAINE DISORDERS.
    Synonyms : 5-HT Agonist, 5-HT1 Agonist, 5-HT1 Agonists, 5-HT2 Agonist, 5-HT2 Agonists, 5-HT3 Agonist, 5-HT3 Agonists, 5-Hydroxytrytamine Agonist, Receptor Agonists, Serotonin, Serotonergic Agonist, Serotonergic Agonists, Serotonin Agonist, Serotonin Receptor Agonist
  • Serotonin Antagonists - »õâ Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonin agonists.
    Synonyms : Antagonists, 5-HT, Antagonists, 5-Hydroxytryptamine, Antagonists, Serotonin, 5 HT Antagonists, 5 Hydroxytryptamine Antagonists, Agents, Antiserotonergic, Antagonists, 5 HT, Antagonists, 5 Hydroxytryptamine, Blockaders, Serotonin
  • Serotonin Plasma Membrane Transport Proteins - »õâ Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.
    Synonyms : 5-Hydroxytryptamine Plasma Membrane Transport Protein, 5HT Transporter, Platelet Serotonin Transporter, SERT Proteins, Serotonectin, Serotonin Transporter, Serotonin Transporter, Platelets, Sodium-Dependent Serotonin Transporter, Transporter, Serotonin
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serotonin a neurotransmitter involved in e.g. sleep and depression and memory
Ãâó: wordnet.princeton.edu/perl/webwn
serotonin A hormone found in the brain, platelets, digestive tract, and pineal gland. It acts both as a neurotransmitter (a substance that nerves use to send messages to one another) and a vasoconstrictor (a substance that causes blood vessels to narrow). A lack of serotonin in the brain is thought to be a cause of depression. Also called 5-hydroxytryptamine.
Ãâó: www.stjude.org/glossary
serotonin a chemical that transmits nerve impulses in the brain, causes blood vessels to constrict (narrow) at sites of bleeding, and stimulates smooth muscle movement in the intestines
Ãâó: www.american-depot.com/services/resources_gl_s.asp
serotonin A vasoconstrictor found in many tissues of the body that is present in relatively high concentrations in portions of the central nervous system (eg, hypothalamus, basal ganglia, etc.). Serotonin functions as a neurotransmitter, regulating the delivery of messages between nerve cells (neurons). This neurotransmitter is thought to play some role in regulating consciousness and mood states. Serotonin is also present in other tissues of the body such as the intestines and blood platelets.
Ãâó: www.dbs-stn.org/glossary4.asp
serotonin (ser-o-to-nin): Neurotransmitter that relays impulses between nerve cells (neurons) in the central nervous system. Functions thought to be regulated by nerve cells that utilize serotonin include mood and behavior, physical coordination, appetite, body temperature, and sleep.
Ãâó: www.indianpsychiatry.com/Glossary.htm
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