| ribonucleinase | <biochemistry, enzyme, molecular biology> Widely distributed type of enzyme that cleaves RNA. May act as endonucleases or exonucleases depending upon the type of enzyme. Generally recognise target by tertiary structure rather than sequence. Ribonuclease E is involved in the formation of 5S ribosomal RNA from pre rRNA. Ribonuclease F is stimulated by interferons and cleaves viral and host RNA and thus inhibits protein synthesis. Ribonuclease H specifically cleaves an RNA base paired to a complementary DNA strand. Ribonuclease P is an endonuclease that generate t RNA from their precursor transcripts. Ribonuclease T is an endonuclease that removes the terminal AMP from the 3' CCA end of a nonaminoacylated tRNA. Ribonuclease T1 cleaves RNA specifically at guanosine residues. Ribonuclease TIII cleaves double stranded regions of RNA molecules. Acronym: RNase (23 Aug 1998) |
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| ribonucleinase | a transferase that catalyzes the hydrolysis of ribonucleic acid |
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