| ¿µ¹® | recessive | ÇÑ±Û | ¿¼º |
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| ¼³¸í | ´ë¸³ÇüÁú Áß ÀâÁ¾ Á¦1´ë¿¡¼ ¼û¾î¼ ³ªÅ¸³ªÁö ¾Ê´Â ÇüÁú. ¿ì¼º¿¡ ´ëÀÀµÇ´Â ¸»ÀÌ´Ù. ³ªÅ¸³ª´Â ÂÊ¿¡ ´ëÇØ ¿¼ºÀ̶ó Çϰí, ±× ÇüÁúÀ» ¿¼ºÇüÁúÀ̶ó°í ÇÑ´Ù. Á¦2´ë(F2)¿¡¼´Â ¿¼ºÇüÁúÀº ºÐ¸®µÇ¾î 1/3ÀÇ ºñÀ²·Î ³ªÅ¸³´Ù. À¯ÀüÀû ´ë¸³ÇüÁú¿¡´Â ¿ì¼º°ú ¿¼ºÀÌ ÀÖ°í, À̰͵éÀº ¿ì¼ºÀ¯ÀüÀÚ¿Í ¿¼ºÀ¯ÀüÀÚ¿¡ ÀÇÇØ Áö¹èµÈ´Ù. ¿¹¸¦ µé¸é, ¾î¶² ¿ì¼ºÇüÁúÀ» Áö¹èÇÏ´Â À¯ÀüÀÚ¸¦ A¶ó Çϰí, ±×°Í¿¡ ´ëÀÀÇÏ´Â ¿¼ºÀ¯ÀüÀÚ¸¦ a¶ó°í Çϸé, ¿ì¼ºÀ¯ÀüÀÚ¸¦ °¡Áø ¾î¹öÀÌ(AA)¿Í ¿¼ºÀ¯ÀüÀÚ¸¦ °¡Áø ¾î¹öÀÌ(aa)ÀÇ ±³¹è¿¡ ÀÇÇÏ¿© »ý±ä ÀâÁ¾ Á¦1´ë(F1)´Â Aa°¡ µÇ¾î ¿ì¼ºÇüÁúÀ» ³ªÅ¸³½´Ù. Aa À¯ÀüÀÚ¸¦ °¡Áø F1³¢¸®¸¦ ±³¹èÇϸé ÀâÁ¾ Á¦2´ë(F2)¿¡¼´Â AA:Aa:aa°¡ 1:2:1ÀÇ ºñÀ²·Î ºÐ¸®µÇ¾î ¿¼ºÇüÁúÀº F2´ë¿¡ 1/3ÀÇ ºñÀ²·Î »ý±ä´Ù. ¿ì¼º-¿¼ºÀ̶õ ÇüÁúÀÇ °¡Ä¡ ¿ì¿À» ¸»ÇÏ´Â °ÍÀÌ ¾Æ´Ï´Ù. ¿¼ºÀÌ µÚ¶³¾îÁ³´Ù´Â ÀλóÀ» Áشٰí ÇÏ¿© ¿¼ºÀ» ÀἺÀ¸·Î, ¿ì¼ºÀ» Çö¼ºÀ¸·Î ÇÏÀÚ°í ÁÖÀåÇÏ´Â ÇÐÀÚµµ ÀÖ´Ù. |
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| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
|---|---|
| AXL | anexelekto [oncogene]; axillary lymphoscintigraphy |
| c-onc | cellular oncogene |
| ONC | oncogene; oncology; Orthopaedic Nursing Certificate; over-the-needle catheter |
| src | Rous sarcoma oncogene |
| c-onc | cellular oncogene |
|---|---|
| GRO-alpha | Growth Regulated Oncogene-alpha |
| GROalpha | Growth-related oncogene-alpha |
| AR | Autosomal Recessive |
| AR-JP | Autosomal recessive juvenile parkinsonism |
| recessive oncogene | <molecular biology> A single copy of this gene issufficient to suppress cell proliferation, the loss of both copies of the gene contributes to cancer formation. (09 Oct 1997) |
|---|
| autosomal recessive | <genetics> Mutation carried on an autosome that is deleterious only in homozygotes. (02 Jan 1998) |
|---|---|
| genes, recessive | Genes that are reflected in the phenotype only in the homozygous state. (12 Dec 1998) |
| recessive | <genetics> An allele or mutation that is only expressed phenotypically when it is present in the homozygous form. In the heterozygote it is obscured by dominant alleles. (18 Nov 1997) |
| recessive, autosomal | A gene on a nonsex chromosome (an autosome) that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, cystic fibrosis (cf) is an autosomal recessive disorder. A cf child has the cf gene on both chromosome 7's (and so is said to be homozygous for cf). (12 Dec 1998) |
| recessive character | An inherited character determined by an allele in homozygous state only. See: dominance of traits. (05 Mar 2000) |
| recessive gene | A gene that is expressed onlywhen it is present in two copies or if theother copy is missing. (09 Oct 1997) |
| recessive inheritance | dominance of traits |
| recessive trait | See: dominance of traits. (05 Mar 2000) |
| recessive, x-linked | A gene on the X chromosome that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, duchenne muscular dystrophy (dmd) is an x-linked recessive disorder. A dmd boy has the dmd gene on his sole x chromosome (and so is said to be hemizgous for dmd). Although it is much rarer, a girl can have dmd (by several different means as, for example, if she has the dmd gene on both her x chromosomes and so is homozygous for dmd). (12 Dec 1998) |
| kidney, polycystic, autosomal recessive | Rare genetic disorder with autosomal recessive inheritance characterised by multiple cysts in both kidneys and associated hepatic lesions. Serious manifestations are usually present at birth and there is high perinatal mortality. (12 Dec 1998) |
| viral oncogene | <molecular biology> A viral gene that contributes to cancer development in vertebrate hosts. (09 Oct 1997) |
| cellular oncogene | <molecular biology> A normal gene that, when mutated or improperly expressed, can cause cancer to develop. (09 Oct 1997) |
| c-oncogene | <molecular biology> A normal gene which has a tumour-producing insert that may have originated from a virus in it, turning it into a proto-oncogene. When these genes are sufficiently mutated, amplified, or over-expressed (transcribed too many times), they can begin to produce cancers. (05 Jan 1998) |
| proto-oncogene | <molecular biology> The normal, cellular equivalent of an oncogene, thus usually a gene involved in the signalling or regulation of cell growth. In general, cellular proto-oncogenes are prefixed with a c, rather than their abnormal viral counterparts, that are prefixed with a v, for example c myc and v myc. They are fragments of DNA, related to oncogenes but are the normal switches used to control growth and tissue repair. (06 Oct 1997) |
| proto-oncogene protein p21(ras) | Cellular protein encoded by the c-ras genes. The protein has GTPase activity and is involved in transmembrane signal transduction as a guanine nucleotide binding protein. Elevated levels of p21 c-ras have been associated with neoplasia. (12 Dec 1998) |
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