| AChRs | Acetylcholine Receptors |
|---|---|
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| 5-HT | 5-Hydroxy-Tryptamine = Serotonin |
| GSCN | giant serotonin-containing neuron |
| GSN | gelsonin; giant serotonin-containing neuron |
| [(3)H]-5-HT | 3)H]-serotonin |
|---|---|
| 5-HT | 3)H]serotonin |
| 5-HT | 5-hydroxytryptophan , a serotonin |
| 5HT | Histamine , serotonin |
| 5-HT | Hypothalamic serotonin |
thromboxane
| receptors, serotonin | Cell-surface proteins that bind serotonin and trigger intracellular changes which influence the behaviour of cells. Several types of serotonin receptors have been recognised which differ in their pharmacology, molecular biology, and mode of action. (12 Dec 1998) |
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| selective serotonin reuptake inhibitor | <pharmacology> This is a class of drug that are used as antidepressants. Functionally, they increase the levels of serotonin in the body. These drugs can be dangerous if they are mixed with other drugs such as other antidepressants, illicit drugs (LSD, cocaine, methamphetamine), some antihistamines (Seldane, Histmanal), some antibiotics, and calcium channel blockers. Side effects include lethargy, confusion, flushing, sweating and muscle spasms. Overdose can cause damage to red blood cells, breathing problems and kidney damage. Examples include: Prozac, Zoloft and Paxil. Acronym: SSRI (12 Jan 1998) |
|---|---|
| serotonin | <biochemistry, hormone> A neurotransmitter and hormone (176 kD), found in vertebrates, invertebrates and plants. It is synthesised from the amino acid tryptophan by enterochromaffin cells in the gut and bronchi. It is metabolised to 5-HIAA in the liver and then excreted in the urine. Serotonin is measured on a venipuncture specimen in cases of suspected carcinoid syndrome (where it will be elevated). The normal range is 101 to 283 ng/ml. Acronym: 5-HT (13 Nov 1997) |
| serotonin agents | Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons. (12 Dec 1998) |
| serotonin agonists | Agents that have an affinity for serotonin receptors and are able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. These compounds are used as antidepressants, anxiolytics, and in the treatment of migraine. (12 Dec 1998) |
| serotonin antagonists | Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonin agonists. (12 Dec 1998) |
| serotonin-binding protein kinase | <enzyme> An aspect of protein kinases EC 2.7.1.37 Registry number: EC 2.7.1.- Synonym: sbp kinase (26 Jun 1999) |
| serotonin uptake inhibitors | Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behaviour, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the adrenergic uptake inhibitors also inhibit serotonin uptake; they are not included here. (12 Dec 1998) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
Synonyms : Receptors, 5-HT, Receptors, 5-Hydroxytryptamine, 5 HT Receptors, 5 Hydroxytryptamine Receptors, Receptors, 5 HT, Receptors, 5 Hydroxytryptamine
Synonyms : 5-HT1 Receptor, 5-HT1 Receptors, Serotonin, 5-HT1 Receptors, 5 HT1 Receptor, 5 HT1 Receptors, 5-HT1 Receptors Serotonin, 5-HT1 Serotonin Receptors, Receptor, 5-HT1, Receptors Serotonin, 5-HT1, Receptors, 5-HT1, Receptors, 5-HT1 Serotonin
Synonyms : 5-HT-2 Receptors, Receptors, 5-HT-2, Receptors, Serotonin S2, Receptors, Serotonin-2, Serotonin S2 Receptors, Serotonin-2 Receptors, 5 HT 2 Receptors, 5-HT2 Receptors, Serotonin, 5-HT2 Serotonin Receptors, Receptors, 5 HT 2, Receptors, 5-HT2 Serotonin
Synonyms : 5-HT3 Receptor, 5-HT3A Receptor, 5-HT3B Receptor, 5-Hydroxytryptamine-3 Receptor, Receptor, Serotonin 3, Receptor, Serotonin, 5-HT3A, Receptor, Serotonin, 5-HT3B, Serotonin 3 Receptors, 5 HT3 Receptor, 5 HT3A Receptor, 5 HT3B Receptor, Receptor, 5-HT3
Synonyms : 5-HT4 Receptor, 5-HT4L Receptor, 5-HT4S Receptor, 5-Hydroxytryptamine-4 Receptor, Receptor, Serotonin 4, Serotonin 4 Receptors, 5 HT4 Receptor, 5 HT4L Receptor, 5 HT4S Receptor, 5 Hydroxytryptamine 4 Receptor, Receptor, 5-HT4, Receptor, 5-HT4L, Receptor, 5-HT4S
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