| ¿µ¹® | opioid | ÇÑ±Û | ¾ÆÆíÀ¯»çÁ¦ |
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| ¼³¸í | 1. ¾ÆÆíÁ¦Á¦¿Í °°Àº ÀÛ¿ëÀ» °¡Áø ÇÕ¼º¸¶¾àÀ¸·Î¼ ¾ÆÆíÀ¯µµÃ¼°¡ ¾Æ´Ñ °Í. Á¾·ù·Î´Â heroin, meperidine, dihydromorphine(Dilaudid), methadone µîÀÌ ÀÖ´Ù. 2. ¼¼Æ÷¸·ÀÇ ¾ÆÆíÁ¦Á¦ ¼ö¿ëü¿Í »óÈ£ÀÛ¿ëÇÔÀ¸·Î½á ¾ÆÆíÁ¦Á¦¿Í °°Àº È¿°ú¸¦ ³ªÅ¸³»´Â õ¿¬»ê ÆéƼµå. |
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| POP | diphosphate group; pain on palpation; paroxypropione; persistent occipitoposterior [fetal position];... |
|---|---|
| AChRs | Acetylcholine Receptors |
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| OR | 1-opioid receptor |
|---|---|
| DOR | Delta opioid receptor |
| EOP | Endogenous opioid peptide |
| KOR | Kappa opioid receptor |
| MOR | Mu opioid receptor |
| receptors, opioid | Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behaviour of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known. (12 Dec 1998) |
|---|---|
| receptors, opioid, delta | A class of opioid receptors recognised by its pharmacological profile. Delta opioid receptors bind endorphins and enkephalins with approximately equal affinity and have less affinity for dynorphins. (12 Dec 1998) |
| receptors, opioid, kappa | A class of opioid receptors recognised by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins which are themselves preferred to enkephalins. (12 Dec 1998) |
| receptors, opioid, mu | A class of opioid receptors recognised by its pharmacological profile. Mu opioid receptors bind, in decreasing order of affinity, endorphins, dynorphins, met-enkephalin, and leu-enkephalin. They have also been shown to be molecular receptors for morphine. (12 Dec 1998) |
| analgesics, opioid | Narcotic or opioid substances, synthetic or semisynthetic agents producing profound analgesia, drowsiness, and changes in mood. Mood changes may be pleasurable, therefore creating a potential for the abuse of these agents; the prototype of these is morphine to which all other analgesics are compared. (12 Dec 1998) |
|---|---|
| mixed opioid agonist-antagonist | <pharmacology> A compound that has an affinity for two or more types of opioid receptors and blocks opioid effects on one receptor type while producing opioid effects on a second receptor type. (13 Nov 1997) |
| opioid | Originally, a term denoting synthetic narcotics resembling opiates but increasingly used to refer to both opiates and synthetic narcotics. (05 Mar 2000) |
| opioid agonist | <pharmacology> Any morphine-like compound that produces bodily effects including pain relief, sedation, constipation and respiratory depression. (16 Dec 1997) |
| opioid antagonists | Agents such as naloxone and naltrexone which have high affinity for opiate receptors but do not activate these receptors. These drugs block the effects of exogenously administered opioids such as morphine, heroin, meperidine, and methadone, or of endogenously released endorphins and enkephalins. (05 Mar 2000) |
| opioid partial agonist | <pharmacology> A compound that has an affinity for and stimulates physiologic activity at the same cell receptors as opioid agonists but that produces only a partial (i.e., submaximal) bodily response. (16 Dec 1997) |
| opioid peptides | The endogenous peptides with opiate-like activity. The three major classes currently recognised are the enkephalins, the dynorphins, and the endorphins. Each of these families derives from different precursors, proenkephalin, prodynorphin, and pro-opiomelanocortin, respectively. There are also at least three classes of opioid receptors, but the peptide families do not map to the receptors in a simple way. (12 Dec 1998) |
| opioid receptor | <pharmacology> A membrane protein, widely distributed in animal cells, but especially in the brain (enkephalin receptors) and gut. The natural ligands are the opiate peptide neurotransmitters, but the name is given because opiates are potent agonists that occupy the receptors and mimic the action of the natural transmitters. (18 Nov 1997) |
| opioid-related disorders | Disorders related or resulting from abuse or mis-use of opioids. (12 Dec 1998) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
Synonyms : Endorphin Receptor, Enkephalin Receptor, Normorphine Receptors, Opiate Receptor, Opiate Receptors, Opioid Receptor, Receptors, Normorphine, Receptors, beta-Endorphin, beta-Endorphin Receptor, Receptor, Endorphin, Receptor, Enkephalin, Receptor, Opiate
Synonyms : delta Opioid Receptor, delta Receptor, Opioid Receptor, delta, Receptor, delta, Receptor, delta Opioid, delta Opioid Receptors
Synonyms : kappa Opioid Receptor, kappa Receptor, Opioid Receptor, kappa, Receptor, kappa, Receptor, kappa Opioid, kappa Opioid Receptors
Synonyms : Morphine Receptor, mu Opioid Receptor, mu Receptor, Opioid Receptor, mu, Receptor, Morphine, Receptor, mu, Receptor, mu Opioid, mu Opioid Receptors
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