| ¿µ¹® | mineralocorticoid | ÇÑ±Û | ¿°·ùÄÚ¸£Æ¼ÄÚÀ̵å, ±¤¹°ÄÚ¸£ÄÚÀ̵å |
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| ¼³¸í | ºÎ½Å°ÑÁú¿¡¼ ³ª¿À´Â È£¸£¸óÁßÀÇ Çϳª. ÀÌ È£¸£¸óÀº »ç¶÷ÀÇ ±¤¿°(¶Ç´Â ÀüÇØÁú: mineral salts, or electrolytes)ÀÇ ¾çÀ» Á¶ÀýÇÏ´Â °¡Àå Áß¿äÇÑ ÀÎÀÚ´Ù. À̵éÀº ü³»¿¡ Á¸ÀçÇÏ´Â ¹°°ú À̿¾çÀ» Á¶ÀýÇÔÀ¸·Î½á, À̸¥¹Ù Àû´çÇÑ Ã¼³»È¯°æÀ» ¸¸µé¾î ÁÖ´Â °ÍÀÌ´Ù. ÀÌÁß °¡Àå Áß¿äÇÑ È£¸£¸óÀº ¾Ëµµ½ºÅ×·ÐÀ¸·Î ±â´ÉÀº, ÄáÆÏ¿¡¼ ³ªÆ®·ýÀÇ Èí¼ö¸¦ Áõ°¡½Ã۰í, Ä®·ýÀÇ ¹è¼³À» ÃËÁøÇÔÀ¸½á ü³» ¼öºÐÀÇ ¾çÀ» Á¶ÀýÇÑ´Ù. |
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| AChRs | Acetylcholine Receptors |
|---|---|
| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
| M-C | mineralocorticoid |
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| AME | Apparent Mineralocorticoid Excess |
|---|---|
| MC | Mineralocorticoid |
| MR | Mineralocorticoid |
| MR | Mineralocorticoid receptor |
| hMR | human mineralocorticoid receptor |
| receptors, mineralocorticoid | Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone. (12 Dec 1998) |
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| mineralocorticoid | 1. <biochemistry> Any of the group of C21 corticosteroids, principally aldosterone, predominantly involved in the regulation of electrolyte and water balance through their effect on ion transport in epithelial cells of the renal tubules, resulting in retention of sodium and loss of potassium, some also possess varying degrees of glucocorticoid activity. Their secretion is regulated principally by plasma volume, serum potassium concentration and angiotensin II and to a lesser extent by anterior pituitary ACTH. 2. <pharmacology> Of, pertaining to, having the properties of or resembling a mineralocorticoid. (12 Jan 1998) |
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| hormone, mineralocorticoid | A group of hormones, the most important being aldosterone, that regulate the balance of water and electrolytes (ions such as sodium and potassium) in the body. The mineralocorticoid hormones act specifically on the tubules of the kidney. (12 Dec 1998) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, alpha-1 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-1 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, alpha-2 | A subclass of alpha-adrenergic receptors (receptors, adrenergic, alpha). Alpha-2 adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and vascular smooth muscle, as well as both pre- and postsynaptically in the central and peripheral nervous systems. (12 Dec 1998) |
| receptors, adrenergic, beta | One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta distinction was originally based on the cellular effects of receptor activation but now relies on the relative affinities for characteristic synthetic ligands. Beta adrenergic receptors are further subdivided based on information from endogenous and cloned receptors. (12 Dec 1998) |
| receptors, adrenergic, beta-1 | A subclass of beta-adrenergic receptors (receptors, adrenergic, beta). Beta-1 adrenergic receptors are equally sensitive to epinephrine and norepinephrine and bind the agonist dobutamine and the antagonist metoprolol with high affinity. They are found in the heart, juxtaglomerular cells, and in the central and peripheral nervous systems. (12 Dec 1998) |
Synonyms : Corticoid I Receptor, Corticoid Type I Receptors, Mineralocorticoid Receptor, Receptors, Corticoid I, Receptors, Corticoid Type I, Receptors, Mineralocorticoids, Corticoid I Receptors, Mineralocorticoids Receptors, Receptor, Corticoid I
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