| AChRs | Acetylcholine Receptors |
|---|---|
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| END | early neonatal death; endocrinology; endorphin; endothelin |
| ENDR | endothelin receptor |
| ENDRB | endothelin receptor B |
| 125I-ET-1 | 125I-endothelin-1 |
|---|---|
| BIG-ET | BIG-endothelin |
| Big ET-1 | Big endothelin-1 |
| ET | Endothelin |
| ET-1 | Endothelin |
| receptors, endothelin | Cell surface proteins that bind endothelin with high affinity and trigger intracellular changes which influence the behaviour of cells. (12 Dec 1998) |
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| endothelin | <protein> Group of peptide hormones released by endothelial cells. The most potent vasoconstrictor hormones known. Structurally related to the snake venom sarafotoxins. (18 Nov 1997) |
|---|---|
| endothelin-1 | A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin-2 | A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts produced in the myocardium, placenta, and uterus, but the cells of origin are not clear. Endothelin-2 has no unique physiologic functions, as compared with endothelin-1. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin-3 | A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin receptor | Simple squamous epithelium lining blood vessels, lymphatics and other fluid filled cavities (such as the anterior chamber of the eye). Mesodermally derived, unlike most epithelia. (18 Nov 1997) |
| endothelin-valine-generating endopeptidase | <enzyme> Cleaves big endothelin between val22 and asn23 Registry number: EC 3.4.21.- Synonym: big-et-ge (26 Jun 1999) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |
| ANP receptors | Cell surface receptors for atrial natriuretic peptide that have a single transmembrane spanning element; these have integral kinase and guanylate cyclase domains. (05 Mar 2000) |
| B-cell antigen receptors | In the primary immune response immunoglobulin D and monomeric immunoglobulin M are the B-cell antigen receptors. On memory B-cells, other immunoglobulin molecules can serve as antigen receptors. (05 Mar 2000) |
| beta-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as propranolol, to block only some adrenergic receptor's and of other agents, such as isoproterenol, to activate only the same adrenergic receptor's. Such receptor's are designated as beta-receptors. Their activation results in physiological responses such as increases in cardiac rate and force of contraction (b1), and relaxation of bronchial and vascular smooth muscle (b2). (05 Mar 2000) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| receptors, adrenergic | Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of g-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (12 Dec 1998) |
| receptors, adrenergic, alpha | One of the two major pharmacological subdivisions of adrenergic receptors. The alpha-beta distinction was originally based on cellular effects of receptor activation but now relies on the relative affinities for certain synthetic ligands. Alpha-adrenergic receptors are further subdivided into several subclasses based on studies of endogenous and cloned receptors. (12 Dec 1998) |
Synonyms : Endothelin Receptor, Endothelium Derived Vasoconstrictor Factor Receptors, Receptors, Endothelins, Receptor, Endothelin, Receptors, Endothelium Derived Vasoconstrictor Factor
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